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CBD Oil for Cancer 2022 ➡️ Best CBD Oil for Cancer

Since the beginning of modern science, we have made significant steps towards developing an effective treatment against cancer. While many of these treatments have saved lives, they usually come at a cost, and many cause debilitating side effects that make cancer treatment all the more difficult.

However, there seems to be hope, with CBD oil for cancer showing promising results in stopping the growth of tumors preventing the formation of tumors, and helping alleviate side effects of conventional cancer treatment.

While more research needs to be done, initial research shows that CBD oil for cancer can be a breakthrough or complementary treatment that can be used alongside other cancer treatments. And even better is the fact that CBD oil for cancer has been developed for both humans and pets.

How effective is CBD Oil for Cancer Treatment?

CBD has been shown to “successfully induce cell death, impede invasion and metastasis in cultured cells, reduce tumor size, vascularization, growth, and weight, and increase survival and induce tumor regression,” according to a review of CBD as an anti-cancer drug.

Cannabinoids’ therapeutic effects have been primarily attributed to their impact on the human body’s endocannabinoid system (E.C.S.). The endocannabinoid system is a complex cell signaling system involved in regulating critical bodily functions and the maintenance of biological homeostasis.

Cannabidiol provides anti-inflammatory, antioxidant, analgesic, and anxiolytic benefits by acting on various cannabinoid receptors in the E.C.S.

What is the Best CBD Oil for Cancer: Top 10 CBD Oils for Cancer in 2022

With CBD oils popping up everywhere, it might be challenging to find the best CBD oil for cancer treatment that is not only safe but effective for you. We have compiled a list of our highly rated CBD oils that have undergone third-party testing, made by reputable brands, and which have been made in sanitary GMP-certified labs.

1. CBDfx

T his CBD tincture oil is made in California by a company founded in 2014. This oil formula contains full-spectrum CBD and is gluten-free and vegan. According to the company, the oil itself has been subjected to rigorous third-party testing eight times.

The hemp used in CBDfx oil is organically grown. This oil is both non-GMO and gluten-free.

CBDfx Oil

✓ 100% organically grown full-spectrum CBD
✓ No cheap or filler ingredients
✓ cGMP-certified and made in the USA
✓ Contains less than 0.01% THC

Prices range between $30.00 to $60.00

Try CBDfx Oil !

2. American Shaman CBD

This CBD oil formula is gluten-free and contains terpene-infused ultra-concentrated hemp oil. The CBD full spectrum in this Oil is extracted using CO2, a method that removes harmful contaminants like heavy metals. The formula is also made with proprietary nanotechnology, which makes it water-soluble. A milligram of American Shaman contains 10mg of CBD.

American Shaman CBD Oil

✓ It eases joint and muscle pain.
✓ Eases headaches
✓ Contributes to better mood
✓ Helps hydrate skin

Price: $59.99 a Bottle

Try American Shaman CBD Oil !

3. Sunday Scaries CBD

Sunday Scaries are made by a transparent company that is open about how their products are made. According to the oil’s creators, the hemp used in their formula was legitimately sourced from farms in Greeley, Colorado.

Sunday Scaries comes in a single flavor, vanilla ice cream flavor, and helps with anxiety and pain that may be as a result of cancer treatment. Developers of this oil recommend a daily dosage of 10mg, close to a third of a dropper.

Sunday Scaries CBD Oil

✓ Deal with anxiety, stress, and depression.

✓ Better sleep.

✓ Improve mood.

✓ Promotes active mindfulness and concentration.

✓ Improved overall health.

Price: $59 a Bottle

Try Sunday Scaries CBD Oil !

4. CBD MD

The oil contains a proprietary broad-spectrum CBD with negligible T.H.C. levels. The hemp used in this oil’s formula, according to the manufacturer, is sourced from farms all over the United States.

To ensure customer safety, both the farms and CBD MD send the ingredients to the International Organization for Standardization for third-party testing (ISO). If that weren’t enough, the ingredients were tested by FDA-registered and GMP-certified third-party contract manufacturers.

CBDMD Oil

✓ Superior Broad Spectrum hemp extract
✓ Made with MCT Oil
✓ Choose from Orange, Berry, Mint, or unflavored Natural
✓ Vegan and Gluten-Free

Prices range between $30.00 to $60.00

Try the Best CBD Oil!

5. CBDistillery

The brand is U.S. Hemp Authority (USHA) certified, which speaks to its credibility, seeing that it underwent third-party auditing and passed. Besides that, it has a brand membership in the National Hemp Association and even the U.S Hemp Roundtable.

The brand sources hemp from open-air farms in Colorado, Kentucky, and Oregon. It ensures that the hemp is grown organically, free from chemicals and pesticides. The facility where the oil is made has the approval of the Colorado Department of Public Health and Environment and is GMP-Certified.

CBDistillery Oil

✓ Non-GMO
✓ NO Pesticides
✓ Coconut MCT oil and hemp oil extract
✓ Thc 0%

Prices range between $30.00 to $60.00

Try the Best CBD Oil!

6. Chill Plus CBD

This CBD oil contains an equal amount of Delta-8 and all-natural, hemp-derived full-spectrum CBD. It’s organic and grown on non-GMO farms, just like the rest of our products. The Chill Plus CBD oil formula contains an equal amount of CBD and delta-8 T.H.C., a close relative of Delta-9 T.H.C. Delta-8 T.H.C. gives you a legal “high” that relaxes and prepares you to sleep.

The potency of this oil ranges between 1000 and 1500 milligrams; according to user feedback, the oil takes effect twenty minutes after use. It has a concentration of 50mg per 1 ml.

Chill Plus CBD Oil

✓ It eases joint and muscle pain.
✓ Extracted from plants grown
✓ Non-GMO farms

✓ Better sleep.

Prices range between $30.00 to $60.00

Try the Best CBD Oil !

7 . Cornbread CBD

The CBD full-spectrum and organic ingredients are USDA organic approved and ideal for aching knees, shoulders, elbows, hands, and muscles. The hemp used in the formulation of this oil is organically grown in Kentucky, a state known for producing high-quality hemp due to its ideal climate, soil, and water.

Cornbread CBD Oil

✓ It eases joint and muscle pain

✓ Deal with anxiety, stress, and depression.

✓ Better sleep.

Prices range between $30.00 to $60.00

Try Cornbread CBD Oil !

8. Joy Organics

Joy Smith founded the company behind this oil in 2018 after struggling with pain and sleep. The oil is subjected to rigorous third-party testing, which includes posting third-party reports for each batch of raw PCR hemp oil, posting third-party reports for finished reports, and including Q.R. codes that, when scanned, provide a profile of the product. IS0/IEC 17025 certified facilities perform third-party testing on the oil. The formula aids in the improvement of sleeping habits and the reduction of anxiety.

Joy Organics CBD Oil

✓ Reducing stress decreasing physiological effects
✓ Improving symptoms of post-traumatic stress disorder
✓ Inducing sleep in cases of insomnia
✓ Support for normal, everyday stresses

Prices range between $30.00 to $60.00

Try Joy Organics CBD Oil !

9. Nuleaf Naturals

This oil is produced by a more established company founded in 2014. This oil has a very high potency level, averaging 60mg per ml. The Nuleaf Natural is available in five different strengths, ranging from 5ml to 100ml, with CBD concentrations ranging from 300 to 6000mg. This oil is made from hemp seed and does not contain any flavorings.

Nuleaf Naturals Oil

✓ Made from full-spectrum hemp extract
✓ Better sleep.

✓ It eases joint and muscle pain.

Prices range between $30.00 to $60.00

Try Nuleaf Naturals Oil !

10. Lazarus Naturals

The hemp used to make this product is organically grown, with 70% coming from a company-owned farm in Oregon. The hemp, which accounts for 30% of the product, is sourced from farms certified by the Oregon Department of Agriculture and Health Research. The CBD in the formula is extracted using CO2, which ensures that it is free of harmful substances and metals. It’s made in a GMP-certified facility.

The oil is subjected to quality and safety testing by the American Herbal Pharmacopeia Monographs. Third-party testing is performed on the oil at Columbia Laboratories, an ISO-17025-certified facility. The recommended dosage is 12 drops per dropper, containing 25mg of CBD.

Lazarus Naturals CBD Oil

✓ Earthy and natural—with no added flavor

✓ Great for promoting relaxation

✓ Relieving inflammation, and supporting overall well-being.

Prices range between $30.00 to $60.00

Try Lazarus Naturals CBD Oil !

How to take CBD Oil for Cancer pain? Is CBD Oil Good for Cancer

We recommend starting with 10 to 20 mg per day unless your doctor advises otherwise. Take it for a week to ensure it’s well-tolerated and that you don’t have any negative side effects or an allergic reaction. If this dose does not produce the desired effect, gradually increase by 5mg every week until the desired amount is obtained.

You can add your daily dosage to a glass of water and drink it or drop it under your tongue and hold it for 30 to 60 seconds before swallowing. And although CBD does not cure cancer, it has been shown to slow down the growth of cancer and helps alleviate some of the side effects common with cancer treatment. CBD oil for cancer treatment helps with:

Helps reduce nausea

Cancer therapy can cause nausea and vomiting, which are serious side effects. Nausea and vomiting are common side effects of cancer treatment and affect most patients who receive chemotherapy. According to cancer.gov, nausea and vomiting are also side effects of radiation therapy to the brain, gastrointestinal tract, or liver, according to cancer.gov.

It is critical to prevent and control nausea and vomiting in cancer patients to continue treatment and carry out daily activities. Uncontrolled nausea and vomiting can result in the following: Changes in the body’s chemical composition, Changes in mental state, loss of appetite, malnutrition, dehydration, a torn esophagus, broken bones, and surgical wound reopening.

Because CBD interacts with serotonin receptors, animal studies suggest that it may help alleviate nausea. This hormone impacts how you feel, specifically your emotions and overall feeling of well-being.

Alleviating Pain

Sometimes, cancer is synonymous with chronic pain, which can make it even more difficult for people with cancer due to day-to-day function. Oftentimes, the pain is caused by nerve changes.

Several reasons could cause these changes to the nerve. First, these nerve changes could result from cancer pressing on nerves or due to chemicals produced by a tumor. It can also be brought on by nerve changes resulting from cancer treatment. Chronic pain, ranging from mild to severe, persists long after the injury or treatment has ended. It may be present at all times, according to cancer.org.

CBD oil for cancer could be a safer alternative for people suffering from chronic pain who are currently reliant on medications such as opioids. Unlike opioids, CBD oils are not only effective but also not habit-forming. Besides that, CBD oils have fewer side effects compared to opioid painkillers.

Helps Reduce Inflammation

Chronic inflammation can damage D.N.A. and lead to cancer over time. People with chronic inflammatory intestinal diseases, such as ulcerative colitis and Crohn’s disease, are often at higher risk of developing colon cancer, according to cancer.org.

However, there seems to be a glimmer of hope for people looking to reduce and even prevent inflammation. Research on the effects of CBD on pain has revealed that CBD helps reduce chronic pain by affecting endocannabinoid receptor activity, reducing inflammation, and interacting with neurotransmitters.

CBD has been shown in clinical studies to reduce the levels of pro-inflammatory cytokines, inhibit T cell proliferation, induce T cell apoptosis, and reduce immune cell migration and adhesion.

Stimulate Appetite

According to Cancer.net , appetite loss or poor appetite is not uncommon in cancer patients. Loss of appetite could result from cancer itself or the treatment. Appetite loss is mainly characterized by eating less than usual not feeling hungry or full after eating a small amount of food.

Unresolved appetite loss has the potential of causing severe complications such as weight loss, malnutrition, fatigue, and weakness from muscle loss. These complications can be a fatal and slow recovery and lead to breaks in treatment.

While there are drugs that can help stimulate appetite, they often come with a host of side effects. In some studies, CBD has been shown to increase appetite. CBD relieves nausea and can calm your nervous system and digestive tract. As CBD has a calming effect on the digestive tract and reduces nausea, you will find cancer patients can eat more. Besides that, CBD also relieves pain, and feeling less pain may increase appetite.

CBD oil for Lung Cancer

British doctors published an article in the journal B.M.J. Case Reports. The report was based on a woman in her 80s with lung cancer who took CBD oil and experienced tumor regression. The tumor continuously shrank for three years. All the while, the woman refused surgery but revealed she took 0.5ml of CBD daily.

CBD oil for Prostate Cancer

A study published in 2012 showed that non-THC cannabinoids such as CBD inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms. The study showed that Cannabidiol (CBD) significantly inhibited prostate cancer cell viability.

CBD oil for Breast Cancer

Pain, fatigue, nausea, discomfort, and anxiety are all common side effects of breast cancer. CBD is used to shrink tumors and alleviate the side effects of breast cancer treatment. It accomplishes this by interacting with the body’s endocannabinoid system, a complex network of receptors on cells that regulate daily body functions like inflammation, mood, and sleep. And it is through this interaction the body can deal with the side effects of cancer treatment.

CBD oil for Colon Cancer

Colorectal cancer (C.R.C.) is now regarded as the third most lethal and fourth most commonly detected cancer globally. Research has shown that CBD has antitumor activity properties in colorectal cancer models. CBD protected D.N.A. from oxidative stress, increased endocannabinoid levels, and inhibited colorectal cancer cell proliferation in some in vitro studies.

CBD oil for Liver Cancer

Research on CBD oil’s effect on patients with liver cancer and who have exhausted all treatment options are still ongoing at the University Medical Centre Groningen (UMCG), Netherlands.

CBD oil for Skin Cancer

Cannabinoids have the potential to be used as an anti-inflammatory agent for skin conditions and have anti-cancer properties. Cannabinoids have been shown to counteract this by producing anti-inflammatory effects and acting as protective agents in neuroinflammatory disorders, making them an excellent candidate for skin cancer treatment.

Skin inflammation, among other things, increases the risk of skin cancer by increasing pro-inflammatory cytokines and activation cascades. Inflammatory cytokines, proteases, and chemokines have been shown in studies to be involved in the survival and invasion of skin cancer cells.

CBD oil for Pancreatic Cancer

Although adequate research on the effectiveness of CBD in its treatment is lacking, there exists some research.

An example of such research is the 2019 review that sought to examine the anti-cancer properties of cannabinoid extract. The review involved vitro and Vivo studies on the effect of cannabinoids in pancreatic cancer, and the studies showed that these extracts could effectively act against pancreatic cancer. However, the research remained unclear on the lack of dosage, formulation, and mode of action.

When to take CBD oil for cancer?

Once you establish a dosage that fits your needs, you can break the dosage into two, taking the first dose in the morning and the second dose in the evening.

CBD oil dosage for Cancer – How much CBD oil should you take?

We recommend that you start on a lower dose and work yourself up to a higher dose. Some health experts recommend that you begin with a daily dosage of 10 to 20 mg per day. It is advised that you take a particular dosage for a week to ensure that it is well-tolerated and that you do not experience any adverse side effects or an allergic reaction.

If this dose does not produce the desired effect, try increasing it by 5mg every week until the desired dosage is achieved.

How long does it take for CBD oil to kick in for cancer?

A lot goes into determining how long it will take for your CBD oil for cancer to kick in, and your weight and metabolism play a massive role in how fast you will receive relief, for starters. Thirdly, the potency of the CBD oil for cancer you settle on will also affect how soon you feel the effects of the CBD.

However, scientists say that you should feel the effects of the CBD, 15 to 45 minutes of taking the dose. Accurate dosage of your preferred dosage should remain effective for 2 to 6 hours. If the effects do wear off, do consider topping off your dosage.

Can CBD oil be used for pets with cancer?

Chemotherapy and radiation are brutal for anyone, our furbabies included. CBD oil for cancer is an excellent complementary treatment that will unfortunately not cure cancer but blunt the side effects of the more traditional medicine.

The CBD oil will ease pain and inflammation, reduce anxiety, seizures, stress, and help with nausea. In some cases, CBD has been proven to slow down the growth of cancer cells, reducing the rate at which cancer is spreading in the body.

And though CBD oil is beneficial for pets with cancer, laws governing its use vary from state to state. Veterinarians are prohibited from initiating or encouraging conversation on CBD products in states like California. While this may be the case, you are free to discuss the benefits and the risks involved with the use of CBD products and their dosage recommendation for your pet.

Is CBD oil safe for cancer?

While CBD oil is well tolerated and safe to use without the risk of developing a dependency, CBD products for cancer have yet to be approved by the Food and Drug Administration (F.D.A.). The F.D.A. has not approved CBD oils to treat cancer or symptoms of cancer or even to help alleviate side effects of cancer treatment.

Despite this fact, the health benefits of CBD oil for cancer outweigh any risks. According to health experts, it is impossible to overdose on CBD oils, as it is a fat-soluble (lipophilic) that compounds in your body over time, offering you even more health benefits.

And you might be wondering if there are any side effects that you should be aware of as you use CBD oil for cancer.

CBD Oil for Cancer Side Effects

CBD is an otherwise safe product to use with very few side effects. Side effects resulting from CBD oil are a result of the impurities intentionally or unintentionally added into the CBD to either increase potency or yield.

However, it is also important to note that people respond to CBD oil differently, and what works for one person may not work for another. CBD oil may cause some individuals to experience mild side effects such as fatigue, diarrhea, appetite changes, and weight changes in isolated cases.

It is also important to note that CBD oil may interact with some medication you might already be on, such as antibiotics, antidepressants, antianxiety medications, sleep aids, muscle relaxers, chemotherapy drugs, anti-seizure drugs, and blood thinners.

For this reason, it is highly recommended that you speak to your health care provider to establish whether the CBD will interact with your medication and even suggest a dosage appropriate for you and your symptoms.

CBD Oil for Cancer Results Before and After:

To enjoy the full benefits of CBD oil for cancer, we recommend that you start on a lower dose and gradually increase it over several weeks. For some side effects caused by the cancer treatment, the relief will occur almost instantaneously, such as pain relief, but complete relief from some will extend to a month.

CBD Oil for Cancer Reviews and rating: Pros and cons:

We have written a raving review for these CBD oils, and you might be asking yourself why I should believe them? For a more objective assessment of some of these supplements, take a look at these:

Positive reviews about CBD oil for cancer

Negative reviews about CBD oil for cancer

  • Alleviates chronic pain
  • Reduces anxiety cause my cancer treatment
  • Improves your appetite
  • Reduces nausea
  • Reduces inflammation
  • Although CBD oil is well tolerated, it does cause some side effects that include drowsiness and dry mouth.
  • May interact with some of the medication you are on

Is it recommended to use CBD Oil for Cancer?

CBD is highly recommended as a complementary treatment for cancer or as a preventative measure against cancer development. Research has shown that CBD can help shrink or stop the growth of a tumor. In addition to this, CBD has been demonstrated to improve the uptake of some cancer treatments, something that enhances the overall results of this treatment.

Where can you buy CBD Oil for Cancer?

Now that you know more about CBD for Cancer, you might be wondering where’s the best place to get these oils from. In a CBD market where some oils are tainted with T.H.C. levels well above the recommended 0.3 percent, you must be very careful with the brands you go for.

Thankfully, the brands listed above have undergone thorough third-party testing that focuses primarily on consumer safety. While buying from the brand is highly advised, it doesn’t offer you options from different brands, so we recommend buying from here.

This site’s purchase ensures that you receive CBD oils directly from manufacturers at a low cost. It is especially recommended that you purchase from this site if you are unsure about the legal status of CBD oils in your state or area.

CBD Oil for Cancer Conclusion – Our experience and recommendation:

Be it for yourself or your pet, we recommend speaking to your physician and veterinarian before starting treatment. By doing this, you will have a basis with your doctor to assess whether the CBD oil is effective or not. And more importantly, a doctor will readily tell you whether your current medication or that of your pet will interact with the CBD oil.

Frequently asked questions about CBD oil for cancer:

Now that you have an idea of how CBD oil for cancer works, here are a few more questions and answers that will help you gain more insight into the product.

How to use CBD oil for cancer?

You should consider several factors when deciding how much CBD to take. These include the CBD oil’s formulation and concentration, the symptoms you’re trying to treat, your age, gender, weight, and overall health. Naturally, people with heavier bodies, on average, need to take a little more to achieve the same results. Men may require a higher dose, whereas older people may require a lower dose. It is also essential to remember that you should always consult your doctor before using CBD oil for cancer. CBD may aggravate symptoms or interact with other medications you are taking.

Where to buy CBD oil for cancer?

According to the American guide for pharmacists, CBD oil should be sold to a patient after explaining what CBD is and how it works. However, CBD laws and regulations in the United States are decided at the state level. The laws and restrictions governing the sale of hemp products differ from state to state, making it risky to travel with CBD products. Presently, 33 states (Alaska, California, Colorado, Maine, Massachusetts, Michigan, Nevada, Oregon, Vermont, and Washington) and the District of Columbia have legalized marijuana. Pharmacists must dispense the products in authorized dispensaries in states such as New York, Minnesota, and Connecticut. If you are not sure where to buy CBD Oil for Cancer, here would be an excellent place to start. The CBD oil for cancer sold on this vendor is bought straight from the manufacturer, guaranteeing your safety. Besides that, this vendor offers you the best prices in the market and delivers in record time.

How much CBD oil should I take for cancer?

Unless your doctor advises otherwise, start with 10 to 20 mg per day. Take it for a week to ensure that it is well-tolerated and that you do not experience any negative side effects or an allergic reaction. If this dose does not produce the desired effect, try increasing it by 5mg every week until the desired amount is obtained.

How much CBD oil should I give my dog for cancer?

Give your pet CBD oil regularly to combat the side effects of cancer and treatment. Dosing twice a day usually yields the best results. The usual dosing guidelines are 1 – 5 mg of CBD per 10 pounds of body weight twice a day, but dosage amounts can vary greatly depending on the situation. CBD oils can be ingested directly from a dropper, mixed into food, sprinkled on treats, or rubbed into bare skin or inside the ears. However, in the United States, veterinarians are not permitted to prescribe or distribute CBD, nor are they authorized to encourage or suggest to clients to purchase CBD products. They are, however, free to discuss the potential benefits and risks of a treatment regimen that you may have to develop on your own. If you want to give CBD to your dog, talk to your veterinarian as well as a vet who has experience with CBD.

What is the best CBD oil for cancer?

his CBD oil formula is gluten-free and vegan, and it contains full-spectrum CBD. According to the company, the oil has been subjected to eight rounds of rigorous third-party testing. CBDfx oil is made from hemp that has been grown organically. This oil is non-GMO as well as gluten-free.

How to use CBD oil for skin cancer?

There have been few clinical trials and scientific studies on CBD oil for skin cancer. And although CBD oil for cancer does not cure cancer, cancer patients may benefit from the anti-inflammatory and pain-relieving properties of cannabidiol oil, regardless of its efficacy in treating skin cancer. When looking for CBD oil, look for a company that uses high-quality hemp-derived cannabis oil. CBD products should be tested for purity and potency by a third-party lab, and any added ingredients should be avoided. There is no benchmark dosage for cannabidiol products, so always follow your doctor’s instructions. Dosing guidelines differ depending on the concentration of the product you choose, so read the package instructions as well.

How to use CBD oil for prostate cancer?

CBD oil for prostate cancer is typically administered by placing one or more drops under the tongue and holding them there for 30 to 60 seconds without swallowing. There is no such thing as a “correct” CBD oil dose. The daily dose can range between 5 mg and 25 mg, depending on your needs and what you’re treating.

How effective is CBD oil for cancer?

There has been a lot of research done on the effectiveness of CBD oil in combating skin cancer. Several studies suggest that using CBD oil in conjunction with other cancer treatment methods can help reduce tumorigenesis at a faster rate. Many studies also indicate that, in some cases, using CBD oil could indeed significantly boost the effectiveness of cancer drugs.

Are there any CBD oil for cancer deals or coupon codes?

Yes! As each brand offers different discount codes and price reductions, trying to locate them and compare which offers the best deal can be difficult. Purchasing from this site guarantees that you get the best deals on the best CBD oils, all without sacrificing quality.

Is it possible to buy CBD oil for cancer on eBay and Amazon?

No. CBD regulations, like marijuana regulations, varied by state and provided that the products are entirely made and sold within a specific state. The federal ban on the cultivation and sale of hemp and hemp-derived products was repealed with the passage of the 2018 Farm Bill. While the federal ban has been lifted, the 2018 Farm Bill did not “legalize” CBD oil sales, contrary to what some brands have claimed. However, because CBD has been approved as a prescription-only drug, all other CBD products that cross state lines are regulated similarly to Class V drugs, which require F.D.A. approval before being sold. Given the varying regulations by state and the F.D.A.’s CBD restrictions, it’s no wonder that e-commerce platforms prohibit CBD oil sales on their sites.

Does CBD oil for cancer have any risks or side effects?

There are no fatal doses of CBD or T.H.C., which is not the case with conventional pain relievers. This is because cannabis does not have the same effect on cardiac activity in the central nervous system as opiates do. However, it is worth noting that the body includes many cannabinoid receptors. As a result, CBD affects the nervous system and several other organs and tissues. Small-scale studies have found that most people tolerate CBD well; however, some individuals may experience mild side effects such as fatigue, diarrhea, appetite changes, and weight changes.

Reference:

  • https://www.uspharmacist.com/article/pharmacists-guide-to-cbd-oil
  • https://innocanpharma.com/cbd-oil-and-skin-cancer-what-does-the-research-say/
  • https://www.verywellhealth.com/cbd-oil-benefits-uses-side-effects-4174562#:~:text=CBD%20oil%20is%20usually%20taken,5%20mg%20and%2025%20mg .
  • https://www.cancer.gov/about-cancer/treatment/side-effects/nausea/nausea-pdq#:~:text=and%20other%20conditions.-,Nausea%20and%20vomiting%20are%20serious%20side%20effects%20of%20cancer%20therapy,also%20cause%20nausea%20and%20vomiting .
  • https://www.healthline.com/health/cbd-for-nausea#:~:text=Animal%20studies%20suggest%20that%20CBD,general%20sense%20of%20well%2Dbeing .
  • https://www.cancerresearchuk.org/about-cancer/coping/physically/cancer-and-pain-control/causes-and-types#:~:text=Chronic%20pain,-Chronic%20pain%20can&text=Nerve%20changes%20may%20be%20due,be%20there%20all%20the%20time .
  • https://www.cancer.gov/about-cancer/causes-prevention/risk/chronic-inflammation#:~:text=Over%20time%2C%20chronic%20inflammation%20can,increased%20risk%20of%20colon%20cancer .
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/#:~:text=Therefore%2C%20it%20has%20been%20suggested,of%20immune%20cells%20%5B66%5D .
  • https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/eating-problems/poor-appetite.html#:~:text=Cancer%20and%20its%20treatment%20can,few%20days%20usually%20lose%20weight .

Dr. ALAN CARTER PHARMD

Dr. Alan Carter is a clinical pharmacist with interests in medical research, pharmacy practice, and drug therapy management. He graduated from the University of Missouri-Kansas City School of Pharmacy. He currently serves as a research pharmacist, clinical pharmacy specialist, and associate clinical assistant professor of pharmacy. Dr. Carter has published 19 journal articles, reviews medical journals, and serves on numerous professional committees and boards. He enjoys gardening, hiking, and other outdoor activities to create a healthy work-life balance. Dr. Alan Carter is also writing for familyfoodandtravel.com.

CBD Oil for Skin Cancer – Benefits & Top Brands of 2022

While CBD oil isn’t the forefront treatment for skin cancer, there’s evidence that supports its use as an adjunctive therapy and a way to deal with the nasty side effects of chemotherapy.

CBD has been making big headlines in the skincare space, but now it’s being examined as a potential therapeutic compound in the treatment of a wide range of skin conditions, including cancer.

Previously, research has shown that CBD can help people with epilepsy, loss of appetite or anorexia, irritable bowel syndrome, and various types of autoimmune disorders.

While there are plenty of CBD-based topical products out there, not all CBD extracts are sourced the same — and that’s the biggest problem on the market right now.

Fortunately, there are several reputable companies that you can turn to if you’re looking for the best CBD oils to use for skin cancer.

In this article, I leave no stone unturned while exploring CBD’s potential in that regard.

CBD Oil for Skin Cancer: Highlights

  • CBD triggers specific mechanisms in the body that are responsible for the growth and spread of tumors, such as apoptosis and cancer cell proliferation.
  • CBD may also help with the side effects of conventional skin cancer treatment. CBD can help with pain and inflammation, loss of appetite, nausea, vomiting, and fatigue.
  • CBD has a very good safety profile. It’s well-tolerated by humans in doses as high as 1,500 mg daily.
  • The side effects of CBD are mild and include dry mouth, dizziness, changes in appetite, and diarrhea.
  • That being said, CBD isn’t an acknowledged cancer treatment. Consult its use with your doctor to figure out the right dosage and avoid interactions with other medications.

Best CBD Oils for Skin Cancer

When choosing the recommended CBD oils for my lists, I always follow strict criteria based on quality, safety, and transparency. Each brand from this ranking has been tested for the following:

  • Certificates of analysis from a third-party, ISO 17025-compliant laboratory, including the results for purity.
  • The source of hemp (U.S.-grown, non-GMO, pesticide-free)
  • THC levels (0.3% or less, according to the 2018 Farm Bill)
  • Extraction method

When I was preparing the material for this article, I also checked:

  • The company’s manufacturing practices
  • The potency of CBD
  • Additional ingredients in the product could help with skin cancer or the side effects of cancer treatment.

Finally, I looked at:

  • Customer feedback
  • Whether the company has a history of warning letters with the FDA
  • Whether the company is facing any lawsuits for unsupported health claims

Here are my top picks when it comes to using CBD oil for skin cancer.

1. Royal CBD

Get 15% off all Royal CBD products. Use code “ CFAH ” at checkout.

  • Organic, US-grown hemp
  • Supercritical CO2 extraction
  • Broad product range
  • High-strength options are available
  • Well-designed formulas
  • Flavored with natural ingredients
  • Complete third-party testing profile
  • 30-days Money-Back Guarantee
  • A little bit more expensive than the market’s average (but still worth the price)
  • Not available locally

Royal CBD is one of the best brands if you’re looking for full-spectrum CBD products from organic hemp. The company was launched in 2018 and since then has become a true hemp powerhouse, offering a broad range of products — including CBD oils, capsules, edibles, topicals, and even CBD for pets.

When it comes to skin cancer, two of their CBD products could help improve your quality of life and deal with the effects of cancer. The first one is the full-spectrum 2500 mg CBD oil, which is the strongest product in the company’s line-up. At 83.3 mg of CBD per mL, it can be used to deal with pain, inflammation, loss of appetite, and nausea.

And, if you’re looking to address localized discomfort, the company offers two types of topicals: a calming salve and a roll-on stick. Both products come with 500 mg of CBD and a range of calming ingredients, such as aloe vera, menthol, green tea extract, and arnica.

2. Gold Bee

  • Organic hemp
  • CO2 extraction
  • Infused with superfoods
  • Full-spectrum and broad-spectrum CBD
  • Up to 2500 mg of total CBD
  • Flavored with natural ingredients
  • Pet products
  • 30-day Money-Back Guarantee
  • Limited potency options
  • No isolate-based products

Gold Bee is a great example of a company that combines CBD with other superfoods to leverage synergistic effects between natural compounds. Its products come infused with organic coconut oil and raw honey from Brazilian rainforests, ensuring well-rounded effects and an outstanding flavor experience.

Like Royal CBD, Gold Bee also has a high-strength product line, featuring 2400 mg full-spectrum CBD oil and 2000 mg Pain Freeze roll-on stick; both products are third-party lab tested for quality and safety, including pesticides, solvents, heavy metals, and microbial impurities.

What Exactly Is Skin Cancer?

According to the National Cancer Institute, cancer is a group of related diseases in which the body experiences an abnormal growth of its cells that spread into the surrounding tissue (1).

The human body contains trillions of cells that are constantly growing and dividing to create new cells in balance. When cells suffer from damage or get old, they die and the new ones replace them. Cancer alters this process.

When cancer starts to grow, abnormalities in the process of cell division appear. Malicious cells form, old or damaged cells survive when they should die, and new cells are created for no reason.

Those excessive cells divide rapidly, forming a tumor. The main difference between normal and cancer cells is the rate at which they grow and spread. Cancer cells are less specific than normal cells, but they still influence the healthy molecules, cells, and blood vessels in the surrounding area. This region is known as the tumor microenvironment (2).

When it comes to skin cancer, it involves the same process — but relates to the abnormal growth of skin cells. It may occur on skin that has been exposed to the sun for too long but can also appear in other areas.

How Do You Identify Skin Cancer Types?

In essence, skin cancers can be broken down into two categories: melanoma and non-melanoma skin cancers. It usually starts in the outer layer of the skin where you can see it with the naked eye, so an early diagnosis is a little easier than with other forms of cancer.

The most types of skin cancer are (3):

  • Basal cell carcinoma
  • Melanoma
  • Merkel cell cancer
  • Squamous cell carcinoma

The first two types aren’t as aggressive as the remaining ones.

Basal cells are round cells that occur in the lower epidermis of the skin; they’re involved in 80% of skin cancer cases.

Squamous cells are flat, scaly cells that make up the majority of the epidermis. They are related to approximately 20% of skin cancers, especially in areas of intense sun exposure. Basal cell and squamous cell carcinoma are also known as keratinocyte carcinomas or non-melanoma skin tumors (4).

Merkel cell cancer is highly aggressive doesn’t have such a high-frequency rate as the two above types. It is triggered by the hormone-producing cells found just under the skin, usually on the head and neck area. Researchers also refer to it as neuroendocrine carcinoma of the skin.

Last but not least, melanoma affects the skin cells responsible for pigment production. These cells are called melanocytes and once they become malignant, they contribute to the most severe type of skin cancer.

Rarer forms of skin cancers include skin adnexal tumors, lymphomas, and Kaposi sarcoma.

Common Conventional Treatments for Skin Cancer

Skin cancer is the most prevalent form of cancer in the United State and has grown to a huge public concern. Researchers have been investigating this disease for years, contributing to the development of numerous novel treatments.

Unfortunately, even with these contemporary upgrades, the average cost of skin cancer treatment exceeds $8 billion per year (5).

The most common treatment options for skin cancer include:

  • Cryotherapy
  • Curettage
  • Chemotherapy
  • Excisional surgery
  • Mohs surgery
  • Photodynamic therapy
  • Radiation therapy

Although many modern cancer treatments are more effective than their older counterparts, they are very expensive, and in some cases, the risks still outweigh the benefits.

In a 2018 review of studies published in the International Journal of Molecular Sciences, the authors suggested that phytochemicals may be the next groundbreaking form of skin cancer treatment that is safe, effective, and affordable for patients (6).

Phytochemicals are simply biologically active molecules sourced from plants.

Many phytochemicals demonstrate anticarcinogenic effects due to their antioxidant, anti-angiogenic, anti-proliferative, and anti-inflammatory effects.

Cannabinoids are one group of phytochemicals that appear particularly promising for cancer patients.

Can CBD Oil Help in Skin Cancer Treatment?

Cannabinoids are natural phytochemicals unique to cannabis plants. Cannabidiol (CBD) is the most prevalent cannabinoid in hemp, a low-THC variety of Cannabis sativa, while tetrahydrocannabinol (THC) is more highly concentrated in marijuana.

There’s a significant difference between CBD and THC. While THC can get you high, CBD doesn’t have such properties. For that reason, CBD is also legal on the federal level — and so are hemp-derived products as long as they contain no more than 0.3% THC.

When it comes to using CBD oil for cancer and other variants, there are a few cannabis types to consider. Medical cannabis, also known as medical marijuana, typically contains higher levels of THC next to CBD because such plants come from selective breeding. Hemp-derived CBD, on the other hand, will only have a trace amount of THC.

Hemp-based products are a good place to start for skin cancer, especially if you’re sensitive to the psychedelic effects of THC. They’re also more accessible considering the legal status of hemp and marijuana.

As mentioned, the form you choose depends on the symptoms you’re trying to target and also the type of cancer you are dealing with. CBD oil can boost your endocannabinoid system and reverse some of the tumorigenic processes in your body with the help of other treatments to aid with the side effects from severe diseases like leukemia. CBD topicals can be useful for any flare-ups on your skin that cause localized pain.

Research on CBD Oil and Skin Cancer

  • A 2015 study posted in the Journal of Investigative Dermatology showed that a combination of CBD and THC induced autophagy (the breakdown of redundant cell components while keeping the healthy ones safe) of malignant cells. It also enabled cell death and blocked the spread of cancer cells in vitro (7).
  • Another in vitro study on skin cancer was published in the Journal of Pharmacy and Pharmacology; it showed that mice treated with CBD had 90% fewer melanoma cells (8).
  • Another study posted by the Federation of American Societies for Experimental Biology found that CBD connects to cancerous cells on the skin that contain cannabinoid receptors — explaining the mechanisms behind the two above findings (9).
  • A study from Vanderbilt University showed that CBD blocks angiogenesis, which is the process of providing a tumor with more blood, stimulating its growth and spread in the body. By inhibiting this process, CBD may cause tumor cells to stop receiving blood and die over time as a result (10).

How Does CBD Oil Work for Skin Cancer?

People have been using cannabis as a natural remedy for various conditions, but since the plant has long been kept illegal over the past century, clinical research is lacking when it comes to its benefits for skin cancer.

Fortunately, the past decade yielded numerous studies that made important discoveries about cannabinoids like CBD and THC, as well as their effects on the human body.

The therapeutic properties of cannabinoids are mostly associated with their interactions with the endocannabinoid system (ECS). The ECS is a complex neurochemical signaling system that plays an essential role in regulating important biological processes and in maintaining balance (homeostasis) between other systems and peripheral organs (11).

By acting on cannabinoid receptors in the ECS, CBD offers antioxidant, anti-inflammatory, analgesic, and anxiolytic benefits (12, 13).

Although more studies are needed, the current body of evidence has shown cannabis oil may provide various anti-cancer effects. In a review of the scientific literature relating to CBD as a potential anticancer drug, it has been shown to cause the death of cancer cells, block their migration and invasion (in vitro), reduce tumor size, weight, and vascularization, and increase survival rate on top of inducing tumor regression (14).

The aforementioned features relate to the use of CBD for glioma, a malignant type of brain cancer, but similar effects have been reported in studies examining CBD’s effects on lung cancer and other types like prostate, colorectal, and lymphoma.

So far, the results are promising, but we need to open large-scale clinical trials to make CBD an official cancer treatment according to current procedures.

Applying CBD Oil on Skin Cancer Ways

There are several ways you can use CBD oil for skin cancer. Let’s take a look at the most popular formats.

Tinctures

Tinctures are hemp extracts suspended in carrier oils that boost the absorption of CBD. Using a CBD tincture allows the user to measure out a precise dose; tinctures are usually available in a wide range of potencies, from 100 mg to 5000 mg of CBD. The best CBD oils for skin cancer are made with a full-spectrum hemp extract due to the presence of the entourage effect. CBD tinctures are taken under the tongue to enhance absorption through the capillary glands in the mouth.

Edibles

If you don’t like the taste of full-spectrum CBD oil, edibles offer a good alternative for bringing your daily dose of CBD enjoyably. They usually come as gummies or chocolate bars; the onset of effects is delayed due to the first-pass metabolism in the liver, but on the other hand, they last longer than other forms of cannabidiol.

Capsules

Capsules work similarly to edibles. They don’t work as fast as tinctures or vapes, but instead, they offer longer-lasting effects and a precise dose in each serving. One thing you’re missing with capsules when using CBD for skin cancer is quite a lot of bioavailability. Oral forms of CBD are the least bioavailable of all products, meaning that you’re getting much less CBD from your dose.

Topicals

CBD topicals are applied to the area of the skin that needs to be targeted. You can find a lot of different formulas on the market, including pain relief creams and roll-on sticks. They usually contain a high concentration of CBD due to not-so-obvious absorption rates. They can relieve pain and other symptoms of skin cancer by interacting with cannabinoid receptors in the lower layers of the skin.

Vapes

Vaporization offers the fastest and most bioavailable way to deliver CBD to your system. If you’re using CBD for pain, anxiety, or sleep, vapes produce their effects within minutes because CBD is absorbed by the lung tissue and avoids the liver. That being said, the effects are relatively short-lived, lasting up to 3-4 hours. You should also watch out for products infused with additives like propylene glycol, vegetable glycerin, vitamin E, or MCT oil because they become toxic when heated.

Oromucosal

Oromucosal CBD sprays are applied to the mouth of the cancer patient. The mucus lining in the mouth facilitates faster absorption, spurring the onset of CBD.

Intranasal

Just like oromucosal CBD oils are sprayed into the mouth of the cancer patient, intranasal sprays are applied to the nose. Pain relief CBD sprays may be particularly effective in easing the side effects of an ongoing radiation or chemotherapy session. Again, the mucus lining in the nose is a great place for CBD to get absorbed faster and more effectively.

CBD Alleviating the Side Effects of Skin Cancer Treatment

Current cancer treatment options are very aggressive because they flood the entire body with free radicals, destroying not only the cancerous cells but also the healthy ones.

That’s why cancer patients often experience severe side effects, such as nausea and vomiting, chronic pain, inflammation, fatigue, loss of appetite, and sleeplessness.

On top of possessing anti-cancer properties, CBD can help ease the said side effects by optimizing the endocannabinoid system and acting on over 60 molecular pathways.

For example, CBD can:

  • Reduce the dryness and inflammation of the skin caused by eczema and other internal body organs, easing pain and irritation in skin cancer patients (15). CBD products such as tinctures, capsules, vapes, and topicals can be used to curb inflammation and increase the patient’s comfort.
  • CBD and other cannabinoids can regulate nausea and vomiting through endocannabinoid signaling and their affinity with serotonin receptors (16).
  • Hemp-derived CBD oils are a rich source of antioxidants, which not only help moisturize the skin but also protect cells against the free radical damage induced by cancer treatments and cancer itself (17).
  • CBD can ease Irritable Bowel Syndrome, which is another medical condition that may occur in skin cancer patients after receiving chemotherapy or radiation (18).

Is CBD Oil Safe for Skin Cancer?

CBD is considered a safe substance; it has a very good safety profile, according to WHO’s report from 2017 (19). A review of cannabidiol’s safety and side effects concluded that the compound is safe and tolerated in very high doses, such as 1,500 mg administered daily for several weeks, without dangerous side effects (20).

That being said, CBD may produce a few adverse reactions if you take too much, including:

  • Dry mouth
  • Dizziness caused by a drop in blood pressure
  • Changes in appetite
  • Fatigue
  • Diarrhea

CBD can also interact with a lot of pharmaceutical medications because it targets the same metabolic enzymes (21). Skin cancer patients should always consult their doctor before adding CBD to their routine to make sure no negative interactions occur. The doctor will help you establish the right dosage of both substances aside from the proper timing.

Evidence of CBD Helping With Other Types of Cancer

The first records of CBD’s positive effects on human diseases come from epilepsy patients. It proved effective in patients of all age groups, from children to the elderly. This had motivated researchers to fuel more resources into examining different medical areas where CBD could help, including cancer.

A 2019 study from the Journal of Pancreatic Cancer noted that CBD has numerous benefits when used for pancreatic cancer. The list included slower tumor growth and self-induced death of cancer cells (apoptosis) (22).

Two other studies, published in Oncotarget Open Access Impact Journal and Journal of Neurooncology, have highlighted CBD as a promising agent in killing gliomas (brain tumor) cells. They not only killed the cancer cells but also strengthened the effects of the conventional treatment (23, 24).

Summarizing CBD’s Potential As a Treatment for Skin Cancer

Conventional treatments for skin cancer have their limitations, so any kind of relief is welcomed. CBD has proven to be incredibly useful for cancer patients, including the ones spreading on the skin.

The side effects are usually minimal and range from dry mouth to changes in appetite and occasional dizziness from too high doses of CBD. There’s also a risk of interactions with other medications, so be sure to talk to your doctor before using CBD as an adjunctive treatment for skin cancer.

Keep in mind that CBD isn’t an acknowledged cancer treatment, so it shouldn’t be used as a substitute for other recommended therapies.

Sources:

  1. National Cancer Institute (2022). What is Cancer? Cancer.gov. Retrieved from: https://www.cancer.gov/about-cancer/understanding/what-is-cancer
  2. Wang, J. J., Lei, K. F., & Han, F. (2018). Tumor microenvironment: recent advances in various cancer treatments. European review for medical and pharmacological sciences, 22(12), 3855–3864. https://doi.org/10.26355/eurrev_201806_15270
  3. Transplant Skin Cancer Network. (2021). Types of Skin Cancer. University of California San Francisco. Retrieved from: https://skincancer.ucsf.edu/types-skin-cancers
  4. Nagarajan, P., Asgari, M. M., Green, A. C., Guhan, S. M., Arron, S. T., Proby, C. M., Rollison, D. E., Harwood, C. A., & Toland, A. E. (2019). Keratinocyte Carcinomas: Current Concepts and Future Research Priorities. Clinical cancer research: an official journal of the American Association for Cancer Research, 25(8), 2379–2391. [1]
  5. Guy, G. P., Jr, Machlin, S. R., Ekwueme, D. U., & Yabroff, K. R. (2015). Prevalence and costs of skin cancer treatment in the U.S., 2002-2006 and 2007-2011. American journal of preventive medicine, 48(2), 183–187. https://doi.org/10.1016/j.amepre.2014.08.036
  6. Ng, C. Y., Yen, H., Hsiao, H. Y., & Su, S. C. (2018). Phytochemicals in Skin Cancer Prevention and Treatment: An Updated Review. International journal of molecular sciences, 19(4), 941. [2]
  7. Armstrong, J. L., Hill, D. S., McKee, C. S., Hernandez-Tiedra, S., Lorente, M., Lopez-Valero, I., Eleni Anagnostou, M., Babatunde, F., Corazzari, M., Redfern, C., Velasco, G., & Lovat, P. E. (2015). Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death. The Journal of investigative dermatology, 135(6), 1629–1637. https://doi.org/10.1038/jid.2015.45
  8. Nakajima, J., Nakae, D., & Yasukawa, K. (2013). Structure-dependent inhibitory effects of synthetic cannabinoids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and skin tumour promotion in mice. The Journal of pharmacy and pharmacology, 65(8), 1223–1230. https://doi.org/10.1111/jphp.12082
  9. Blázquez, C., Carracedo, A., Barrado, L., Real, P. J., Fernández-Luna, J. L., Velasco, G., Malumbres, M., & Guzmán, M. (2006). Cannabinoid receptors as novel targets for the treatment of melanoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20(14), 2633–2635. https://doi.org/10.1096/fj.06-6638fje
  10. Shattuck-Brandt, R. L., Chen, S. C., Murray, E., Johnson, C. A., Crandall, H., O’Neal, J. F., Al-Rohil, R. N., Nebhan, C. A., Bharti, V., Dahlman, K. B., Ayers, G. D., Yan, C., Kelley, M. C., Kauffmann, R. M., Hooks, M., Grau, A., Johnson, D. B., Vilgelm, A. E., & Richmond, A. (2020). Metastatic Melanoma Patient-Derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research, 26(14), 3803–3818. https://doi.org/10.1158/1078-0432.CCR-19-1895
  11. Sallabery, C.A. & Astern, L. (2018). The Endocannabinoid System, Our Universal Regulator. Journal of Young Investigators.
  12. van de Donk, T., Niesters, M., Kowal, M. A., Olofsen, E., Dahan, A., & van Velzen, M. (2019). An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia. Pain, 160(4), 860–869. https://doi.org/10.1097/j.pain.0000000000001464
  13. Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a Potential Treatment for Anxiety Disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 12(4), 825–836. https://doi.org/10.1007/s13311-015-0387-1
  14. Seltzer, E. S., Watters, A. K., MacKenzie, D., Jr, Granat, L. M., & Zhang, D. (2020). Cannabidiol (CBD) as a Promising Anti-Cancer Drug. Cancers, 12(11), 3203. https://doi.org/10.3390/cancers12113203
  15. Nagarkatti, P., Pandey, R., Rieder, S. A., Hegde, V. L., & Nagarkatti, M. (2009). Cannabinoids as novel anti-inflammatory drugs. Future medicinal chemistry, 1(7), 1333–1349. https://doi.org/10.4155/fmc.09.93
  16. Parker, L. A., Rock, E. M., & Limebeer, C. L. (2011). Regulation of nausea and vomiting by cannabinoids. British journal of pharmacology, 163(7), 1411–1422. [3]
  17. Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants (Basel, Switzerland), 9(1), 21. https://doi.org/10.3390/antiox9010021
  18. Brugnatelli, V., Turco, F., Freo, U., & Zanette, G. (2020). Irritable Bowel Syndrome: Manipulating the Endocannabinoid System as First-Line Treatment. Frontiers in neuroscience, 14, 371. https://doi.org/10.3389/fnins.2020.00371
  19. World Health Organization. (2018). Cannabidiol (CBD): Critical Review Report. Expert Committee on Drug Dependence, Fortieth Meeting. Retrieved from:
  20. Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, 2(1), 139–154. https://doi.org/10.1089/can.2016.0034
  21. Brown, J. D., & Winterstein, A. G. (2019). Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. Journal of clinical medicine, 8(7), 989. https://doi.org/10.3390/jcm8070989
  22. Sharafi, G., He, H., & Nikfarjam, M. (2019). Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer. Journal of pancreatic cancer, 5(1), 1–7. [4]
  23. Ivanov, V. N., Wu, J., Wang, T., & Hei, T. K. (2019). Inhibition of ATM kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells. Oncotarget, 10(8), 825–846. [5]
  24. Rocha, F. C., Dos Santos Júnior, J. G., Stefano, S. C., & da Silveira, D. X. (2014). A systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas. Journal of neuro-oncology, 116(1), 11–24. https://doi.org/10.1007/s11060-013-1277-1
Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

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CBD for Skin Cancer

Just hearing the word “cancer” can be alarming—and receiving a diagnosis even more so. While skin cancer is more easily spotted and treatable than other types of cancer, it’s still just as frightening when one is diagnosed with it. After all, our skin is our first impression to the world.

Skin cancer is the most common cancer in the U.S., and is a broad term describing an abnormal growth of cells that has the ability to spread. The areas of the body most commonly affected are those that are exposed to the sun, but skin cancer can develop anywhere on the body.

How do most people get skin cancer? Sun exposure—more specifically, exposure to UVB radiation. This type of radiation comes from not only the sun but also sunlamps and tanning booths. Avoiding exposure to UVB radiation and using sunscreen when you are outdoors may help prevent some skin cancers from forming.

Most skin cancers—with the exception of melanomas—do not spread very quickly, if at all, and many can be successfully treated with surgical procedure called excision.

Table of Contents

    • Types of Skin Cancer
    • Animal Studies
    • Human Studies
      • Additional CBD Resources on Cancer

      Types of Skin Cancer

      There are different types of skin cancer. These include:

      • Non-Melanoma Skin Cancer
        • Basal cell carcinoma: Basal cells produce new skin cells, and basal cell carcinomas usually occur on sun-exposed skin and may look like a shiny almost translucent or pearly bump on the skin. But they can also be dark brown, black, or a dark bluish color. Sometimes they are a reddish scaly patch of skin. These types of cancers tend not to spread.
        • Squamous cell carcinoma: Squamous cells make up the middle and outer layers of skin. This type of cancer also appears on skin exposed to sunlight, and it can manifest in different appearances on different parts of your body. This type of cancer can be aggressive, but it also isn’t prone to spreading. Squamous cell carcinoma can look like a nodule (often red), a crusty area on the skin, or a reddened area in the mouth, the anus, and around the genital area.
        • Rarer types include angiosarcomas, cutaneous lymphomas, and others
        • Melanoma is the most dangerous form of skin cancer. It develops in the pigment cells of the skin—the cells that produce melanin.
        • Melanoma can also metastasize, or spread, to other areas of the body. It is metastasis that makes this cancer—and all types of cancers—so dangerous.

        One of the obstacles in catching skin cancer early is that normal skin blemishes, such as moles, are often overlooked for long periods of time as being nothing to worry about. To help distinguish everyday moles from possible melanomas, use the mnemonic “ABCDE.

        • Asymmetric in shape
        • Borders are irregular
        • Changes in color
        • Diameter over ~¼ inch (6 mm)
        • Evolving changes—changes that can include shape, color, size or if a mole begins to bleed or itch

        CBD and Skin Cancer

        Any cell can be transformed into a cancer cell—and there are many, many ways this can happen depending on the specific cell. This is just one of the reasons there may never be a single “cure” for cancer in general; cancer represents well over 100 different types. Each type of cancer may have different mechanisms contributing to its transformation and each may have different points at which it can be treated.

        Underlying all cancers is the regulation of gene expression. For every type of cancer, there is a different gene (or genes) that becomes activated or deactivated causing the cell to become cancerous.

        The functions of the endocannabinoid system—the natural biological system that “overlaps” with plant-derived cannabinoids—include inhibiting tumor cell replication and growth, inhibiting the spread of a tumor (metastasis) partly by inhibiting the growth of new blood vessels, and inducing a form of cell death known as apoptosis.

        Some studies have indicated that poorly functioning endocannabinoid system may set the stage for conditions that allow the cancer cells to proliferate and metastasize. Note the subtle difference between a poorly functioning endocannabinoid system causing the initial transformation of cells into cancer cells and allowing cancer to progress. Think of it as the difference between a water tap where no water flows out at all and a water tap that allows a few drops of water to flow.

        Animal Studies

        In mice, for example, cannabinoids have been shown to reduce the size of breast tumors and lower the frequency of metastasis. Many other studies have indicated that the endocannabinoid system is functional in the skin and may play a role in skin cancers, especially inflammatory skin cancers.

        Animal models have revealed some paradoxical findings—in other words, cannabinoids have been found, under different conditions, to be both supporting cancer cells and inhibiting cancer cells. This is true for both melanoma and nonmelanoma, and may be dose dependent.

        Human Studies

        You probably guessed it—there are very studies on CBD for skin cancer in progress at the moment. For now, though, we have some limited data from studies performed in human cells cultures—but these studies used synthetic cannabinoids and not CBD.

        Summary of the Use of CBD for Skin Cancer

        Currently, there are only theories why CBD for skin cancer might inhibit cancerous cell growth: In particular, CBD’s anti-inflammatory properties (cancer and inflammation go hand-in-hand) and its ability to inhibit the growth of the blood vessels needed to “feed” a tumor. There may also be some more direct effects of cannabinoids on tumor growth and on inducing apoptosis.

        All this taken together shows promise that CBD for skin cancer could play part in future treatment protocols, but more clinical trials and more information are still needed.

        Most of the common skin cancers like squamous and basal cell carcinomas are relatively noninvasive and, if caught early, can be completely removed by excision. The more invasive melanoma form of skin cancer is harder to detect and requires a more extensive treatment protocol including surgery, radiation treatment, and chemotherapy. Early melanoma has a survival rate of 98 percent—but this falls to 23 percent if the melanoma spreads to other parts of the body.

        Early detection is key. This is why if you suspect that a mole on your body has changed, or you have found a new scaly patch on your skin, or you are just not certain if that spot on your skin has always looked like that or not—go see a qualified dermatologist, and follow their treatment advice. If you receive a cancer diagnosis, don’t be afraid to ask your doctor about CBD for skin cancer. Ask them if they know about any new research.