Posted on

Which brand is the best cbd oil for seizures

Best CBD Oil for Seizures in Adults

Suffering from seizures turns our body into a very delicate structure where even a light provocation can result in the occurrence of a seizure. So such people have to be extra careful regarding each sensory aspect of their entire lives.

We understand it’s hard to live this way but know that we are rooting for you to survive the best possible way you can. One way you can improve your health and reduce the instance of seizure is by using CBD as a therapeutic treatment.

Some very focused double-blind studies have shown that CBD has an advanced effect on the diseased state of a person suffering from seizures as CBD is known to reduce the frequency of occurrence of seizures.

And by doing so CBD provides greater control to the person on their own body. To know more about the best CBD oils for seizures in adults, give the following article a thorough read and possibly choose from the best options available in the market.

Our Overall #1 Rated Pick

Spruce 2400mg CBD Oil

  • 100% organic
  • Plant-based
  • Free from dairy mixings
  • Non-GMO verified ingredients

Spruce has a pretty good range of CBD Oils. It has introduced high-quality CBD Oil in the market. The oil is filled with 100% natural and plant-based ingredients. It works well for adults. The oil has safe and pure ingredients.

The hemp seed extract is extracted from large organic farms. Spruce extracts CBD oil from organically grown hemp seed. The extract is then added to the CBD Oil. It promotes relaxation of the body and brain. The oil is good for Adults suffering from depression, anxiety, and stress.

Best CBD Oil for Seizures – Comparison Table

Image

Price

Best CBD Oil for Seizures in Adults – Product Reviews

Top 10 CBD Oil for Seizures in Adults out there

Spruce 2400 mg CBD Oil

Spruce has a pretty good range of CBD Oils. It has introduced high-quality CBD Oil in the market. The oil is filled with 100% natural and plant-based ingredients. It works well for adults. The oil has safe and pure ingredients.

The hemp seed extract is extracted from large organic farms. Spruce extracts CBD oil from organically grown hemp seed. The extract is then added to the CBD Oil. It promotes relaxation of the body and brain. The oil is good for Adults suffering from depression, anxiety, and stress.

The ingredients are non-GMO verified and tested two times. It is tested in the lab during manufacturing and packaging. The samples of the oil are also tested by a third party. The oil is free of toxins, heavy metals, and chemicals.

Spruce 2400 mg is high strength oil. It prevents stress, fatigue, inflammation, and pain. The oil supports the central nervous system and immunity system. It is a full-spectrum oil. The oil has a slight amount of THC. However, the amount is very low.

  • 100% organic
  • Plant-based
  • Free from dairy mixings
  • Non-GMO verified ingredients
  • The oil is full-spectrum
  • It is free from additives
  • The oil is tested
  • It contains THC

Spruce 750mg Lab-grade CBD Oil

Adults need nutrients and vitamins. As you grow your body needs supporting minerals. IT will help your body to function properly. Spruce 750 mg CBD Oil is lab-grade. The oil is filled with natural mixings and is 100% plant-based.

The oil has several benefits. It supports the immunity and digestive system. The oil has vitamins that give you strength. It prevents pain, inflammation, and fatigue. The oil also has natural mixings for improving your sleep cycle.

It also deals quite well with brain disorders. The oil is tested for safety and purity. It is tested in the manufacturing lab. The oil is also examined by a third party. It is tested during processing and packaging. The company makes sure to deliver a quality product.

The hemp seed extract promotes calmness and relaxation. It is obtained from organic farms. The oil has a high absorption rate. It is dissolved quickly into the bloodstream. The ingredients are non-GMO verified and dairy-free.

  • 100% organic
  • The oil is Full Spectrum
  • It is a plant-based oil
  • No artificial ingredients present
  • Lab-grade oil
  • Verified by a third party
  • It includes THC
  • It is not good during pregnancy

Spruce 4800mg Extra Strength CBD Oil

Spruce 400 mg CBD Oil is high potency. The oil is filled with 100% organic, effective, and safe ingredients. It helps to prevent anxiety, stress, and depression. Adults suffering from a brain disorder can also consume CBD Oil.

The oil is completely plant-based. A natural treatment is better than a synthetic one. The oil contains hemp seed extract. The extract is obtained from the farms of Colorado. The hemp seed extract provides relaxation of mind and body.

The oil is full-spectrum. It has additional cannabinoids. The oil has a slight amount of THC. However, the percentage is lower than 0.3. The oil contains non-GMO verified and dairy-free ingredients.

The oil is tested in the lab during manufacturing and packaging. It is also verified safe by a third-party. The oil has fast absorption. It supports the immunity system and promotes a healthy life. The oil improves the sleep cycle and lowers the pain.

  • Oil is pure
  • Plant-based
  • The oil is Full Spectrum
  • No artificial mixings
  • High potency
  • Tested and verified
  • Contains minor traces amount of THC
  • It is an expensive CBD Oil

Spruce 400mg Extra Strength (Sample Size)

Spruce has introduced a sample size oil in the market. The oil has the same benefits. The only difference is the size. It is for people who are buying the oil for the first time. The oil is high in strength and contains premium quality ingredients.

It contains hemp seed extract. The hemp seed promotes a sense of calmness. The oil is full of vitamins and nutrients. It contains minerals for supporting brain health. The oil prevents fatigue, pain, anxiety, and inflammation.

It has ingredients that work wonders in treating pain. The oil does not disturb the immunity system and digestive system. It is a full-spectrum oil. The amount of THC is very low. It contains coconut oil extract.

The oil is tested in small samples at each step. It is also verified by a third party. The oil is free of heavy metals, chemicals, and toxins. The oil contains non-GMO verified and dairy-free ingredients. It is suggested to start with a small dosage.

  • Oil is plant-based
  • It is full-spectrum
  • The ingredients are natural
  • It has no additives
  • The oil is a lab grade
  • It is tested
  • Oil is sample-size
  • It contains THC

Cheef Botanicals CBD Oil

Cheef Botanicals CBD Oil is introduced by health professionals. It is full of safe, pure, and effective ingredients. The oil is a good pick for preventing stress, memory loss, pain, and inflammation. It is a good oil for improving focus and concentration.

The oil contains efficient ingredients. Hemp seed extract provides relaxation and calmness. The oil is tested in the lab and also by a third party. It is free of toxins, contaminants, heavy metals, and chemicals.

The oil contains fatty acids. These are essential nutrients for a healthy brain. The oil supports the nervous system and improves cognition. The oil has no artificial additives and mixings. It is safe and pure. The oil is high potency.

  • It is organic
  • The oil is plant-based
  • It is verified by a third party
  • The oil is tested
  • It is Full-spectrum
  • Non-GMO verified mixings
  • Ingredients are dairy-free
  • The oil is not THC free

CBDistillery CBD Oil

CBDistillery is a high-quality oil. It is worth mentioning CBD Oil. The mixings of the oil are safe, pure, and plant-based. It is a good pick for preventing depression, stress, and fatigue. The oil is free of artificial additives and preservatives.

The oil contains supporting nutrients and minerals for a healthy brain. It supports the central nervous system and immunity system. The oil protects the brain from several disorders. It is a lab-grade oil. The hemp is obtained from organic farms.

The oil is tested during manufacturing and packing. It is also tested by a third-party. The oil is free of toxins, heavy metals, and chemicals. The oil is full-spectrum. It contains a slight amount of THC.

The oil is fast absorbing and it dissolves quickly into the bloodstream. It contains non-GMO verified and dairy-free ingredients. The oil improves cognition, focus, and sleep pattern. It is also very effective for reducing anxiety, pain, and inflammation.

  • It is natural
  • The oil is full-spectrum
  • The oil is plant-based
  • It is free of preservatives
  • It is dairy-free
  • The oil is tested
  • It is an expensive CBD Oil

Verma Farms Natural CBD Oil

Verma Farms was introduced recently in the market. The oil is completely plant-based. It contains nutrients, vitamins, and minerals. The oil is manufactured by a Maui-based manufacturer. It is safe, clean, and pure.

The oil is tested in the lab. It is also verified safe by a third party. The oil work wonders in preventing anxiety, stress, and depression. It supports the central nervous system. The oil builds a protective wall in the brain.

The oil is a good pick for adults suffering from insomnia and chronic pain. It reduces stress and fatigue. The oil also helps to improve the sleep cycle, cognition, and focus. The oil comes in different variants. It contains non-GMO verified and dairy-free ingredients.

  • The oil is organic
  • It is broad-spectrum
  • The oil is THC-free
  • Improves sleep and cognition
  • The oil has fast absorption
  • It is expensive

Joy Organics CBD Oil

Joy Organics CBD Oil contains safe and clean ingredients. The oil is free of artificial mixings and preservatives. It is alcohol-free and a plant-based oil. The oil work wonders for adults suffering from anxiety, stress, dementia, and other brain disorders.

It is also worth buying oil for preventing chronic pain and inflammation. The mixings of the oil are pure and organic. It has hemp seed extract obtained from organic farms. The oil is THC-free. It supports the immunity system.

The oil contains ingredients that promote relaxation and calmness. It is tested in the lab and also by a third party. The oil is free of preservatives, flavors, toxins, and heavy metals. It has a high absorption rate and dissolves quickly into the bloodstream.

  • The oil is 100% natural
  • It high in strength
  • The oil is tested
  • It is THC-free
  • The oil improves cognition
  • It has no preservative
  • It is expensive

Charlotte’s Web CBD Oil

Charlotte’s Web CBD Oil is one of the efficient CBD Oils. The oil is full of organic and plant-based ingredients. It contains safe, clean, and pure ingredients. The oil has supporting vitamins and nutrients for a healthy brain.

It is a good pick for preventing anxiety, stress, and loss of memory in adults. The oil works well in treating chronic pain and inflammation. The oil contains non-GMO verified and dairy-free ingredients. The other mixings are also safe.

The formula of the oil has a high absorption rate. It dissolves fast into the bloodstream. The oil prevents fatigue and improves the sleep cycle. It supports the immunity system. The oil enhances cognition, memory, and focus.

It is tested in the lab and also by a third party. The oil is free of preservatives, additives, and artificial flavors. It is also tested free of heavy metals and toxins. The hemp seed extract is obtained from organic farms.

  • The oil is organic
  • It is full-spectrum
  • The oil is preservatives-free
  • It improves cognition
  • The oil treats pain
  • It prevents memory loss
  • The oil is not economical

CBDfx CBD Oil

CBDfx CBD Oil is a premium-quality and high potency CBD Oil. It is filled with wholesome ingredients. The mixings of the oil are safe, pure, and clean. It is a full-spectrum oil. The THC content is very low.

The oil contains hemp seed extract. It is contained from organic farms. The oil contains vitamins, nutrients, and minerals. The oil does not disturb the digestive system. It prevents anxiety, depression, and stress in adults.

The oil is tested in the lab during manufacturing and packing. Its formulation and procedure are also tested by a third party. The mixings of the oil are gluten-free and non-GMO verified. The oil is free of heavy metals and toxins.

The oil helps to improve cognition, memory, focus, and concentration. It is a good pick for adults suffering from chronic pain and inflammation. The oil is fast in absorption and dissolves quickly into the bloodstream.

  • It is vegetarian
  • The oil is free of additives
  • The oil improves sleep and cognition
  • The oil is full-spectrum
  • The mixings are pure
  • It is expensive

Best CBD Oil for Seizures in Adults – Buying Guide

Dealing with seizures in your routine life is not easy and in such a diseased state, one can find themselves in a conundrum because many things are banned for consumption due to their aggravating effects on the condition.

But luckily CBD is not one of those elements that aggravate seizures on the contrary CBD helps improve the condition towards a more normal and controlled state. With such a delicate system one ought to be as safe as they can.

The following buying contains features that you need to look for in a quality CBD oil to ensure you receive the very best this community has to offer.

Potency

There are two divisions in this category in the common credible market of CBD products, the high potency, and low potency CBD oils. The high potency CBD oils are those where the carrier oil is enriched with CBD to its maximum capability.

With a high potency oil, you receive 80 mg of CBD concentrate with one ml of CBD oil. Whereas with low potency CBD oil you receive 40-35 mg of CBD oil per 1 ml of CBD oil. The number featured on the bottle of CBD oil indicates the total amount of CBD concentrate in the entire bottle and not one dose.

For a condition such as epilepsy strong CBD oil is required to really impart a change in the condition. Even though it will still take a few days for the full benefits to start to appear but we still recommend using the high potency CBD oil for the treatment of seizures if you can live through the bitter taste featured by CBD products

Entourage Effect

The entourage effect explains how a series of elements from the same family work together to enhance the overall functionality and viability of a product. We can see a significant amount of entourage effect going on in full-spectrum and broad-spectrum CBD oils.

These two spectrums contain not just CBD but additional cannabinoid elements as well which enhance the therapeutic benefits of CBD. These additional elements also increase the half-life of CBD and the extent of functionality of CBD as well under the entourage effect.

This effect is the reason we urge our readers to choose either broad-spectrum or full-spectrum CBD oils so they may receive the maximum benefits.

Flavors

The original flavor of CBD is quite bitter hence a little bit of additional flavor doesn’t harm anyone. But there is a limitation that comes around while flavoring is in question especially in high potency CBD oils.

The base oil has a certain level of affinity for different products and it also has a capacity to hold products. When high potency CBD oils are concerned the CBD concentrate maximizes the capacity of the carrier oil to hold product so much so that no additional product can be added.

This is why high potency CBD oils are never flavored and consumers have to bear through the bitter flavor of cannabis. Although the low potency CBD oils do not fill up the concentration limit of the carrier oil hence it can be flavored.

A lot of low potency CBD oils are flavored with interestingly tasty flavors such as orange, strawberry, lavender, etc. That is another one of the reasons why we prescribe starting from a low potency oil to teach you into high potency oils with tastier low potency flavored oils.

Legality

For the longest of times, CBD was banned for consumption in the united states of America and the reason was that it was procured from a plant that was otherwise used for recreation purposes. The plant is cannabis and the recreational purposes are people smoking pot.

But CBD was the sibling that was wrongfully accused of funny side effects of its sibling element THC. When a little light was shed on the subject matter authorities realized that they could extract beneficial compounds out of the cannabis without even having to consume trace amounts of THC.

Hence, CBD was made legal in the states under federal law of The United States of America. But then the entourage effect of THC was discovered and people wanted the collective beneficial effects of the entire plant.

Then a safe limit of THC was introduced and set out to be equal to or less than 0.3 percent. At this minute percentage, THC is devoid of its ability to produce a ‘high’ state in humans. Thus, the legal precedence of CBD products revolves around the percentage of THC it carries.

As long as the concentration remains under 0.3 percent the product is legal to manufacture and safe to consume.

Method of Intake

The method of intake decides the bioavailability of your product. There are two main ways of CBD oil intake. One is the basic ingestion of CBD oil. In this method, all you need to do is measure the CBD oil with a dropper and ingest the required dose.

Your digestive tract will do all the work of absorption and delivery to the circulatory system. But the backfall of this method is that most of the CBD is excreted out of the system unabsorbed or gets destroyed under the powerful action of digestive enzymes.

The other method revolves around the sublingual glands. First, you need to measure out the dose via the dropper that comes along with the CBD oil. Then drop the required dose under your tongue and keep it there for at least 60 seconds.

The significance of this step is such that there are very thin-walled capillaries under the sublingual glands and the sheath covering the base under the tongue is very thin as well both of these membranes easily allow movement of CBD directly into the circulatory system.

This step ensures over 90 percent absorption of CBD into the system thus the bioavailability of CBD offered by this method of intake is the highest. After one minute of holding the CBD oil under your tongue, you can ingest the rest.

Whatever concentration of CBD is left in the oil, can be absorbed by the GIT system thus providing over 90 percent bioavailability.

Frequently Asked Questions

Q. Will the seizures stop after taking CBD?

A. CBD has the tendency to heal the damaged parts of the body by remodifying the chemically altered states. Since seizures are the result of an immense chemical imbalance in the brain there have been instances where CBD has significantly reduced the incidence of seizures in certain diseases such as epilepsy.

Q. Is there an age limit to CBD consumption?

A. According to the rules and regulations set by the FDA the minimum age for CBD consumption is two years. For toddlers, there is also an upper limit for safe consumption of CBD that should be followed to the tee.

Q. Can CBD oil alter the excretion of epilepsy drugs?

A. Even though some studies suggest CBD oil has shown interference with plasma concentrations and excretory process of certain chronic drugs but researches done specifically on the effect of CBD on epilepsy drugs indicates that there is no significant change in the plasma concentrations of epilepsy drugs seen during CBD therapy.

Final Word

Having to deal with such an excruciating disease that causes devastating conditions such as seizures where the body loses all the control on itself can be very daunting. It is very courageous of all the patients out there who are dealing with this condition with perseverance and haven’t lost hope.

Using the best CBD Oil for seizures in adults to reduce the frequency of seizures is the next step in the treatment of diseases such as epilepsy. If one can predict the occurrence of a seizure and reduce its intensity or its occurrence altogether, it will be a revolutionary treatment.

CBD is known to reduce the frequency of seizures to about half. For people suffering from epilepsy, these figures are more than enough. Until science finds a sure-fire treatment of epilepsy CBD is the way to gain a little bit more control over your body.

CBD Oil for Seizures & Epilepsy: How Cannabis Oil Can Stop Seizures

According to the Michigan Epilepsy Foundation, 1% of Americans suffer from some form of epilepsy — a recurring neurological disorder known for frequent, often unprovoked seizures.

Epilepsy compromises all aspects of a person’s daily life. The violent tremors caused by a seizure attack can put the individual in grave danger, not to mention that people with epilepsy are also prone to suffer from sleep issues, migraines, anxiety disorders, and depression.

Of all epilepsy forms, up to 40% is drug-resistant, meaning the patient doesn’t react to Antiepileptic Drugs (AEDs). For these patients, AEDs are simply ineffective, or the side-effects are too severe to allow for continuous treatment.

As a result, many turn to natural resources to help manage their condition. CBD oil is one promising option whose antiepileptic effects have been thoroughly studied by scientists.

In this article, I’ll cover the potential benefits of CBD oil for epilepsy and seizures — and share the top brands I trust when it comes to manufacturing high-quality CBD oil.

Best CBD Oil Brands for Epilepsy & Seizures

There are lots of different CBD companies trying to make their name in the market with their CBD oil. Some brands provide high-quality products and can back up their claims with third-party lab reports. In contrast, others tend to take advantage of unaware consumers with lots of fancy buzzwords and unrealistic promises.

If you want a clean and potent CBD oil, you need to find a manufacturer that makes organic products with proper quality assurance.

Don’t have time for that? Don’t worry — I did the research for you.

Here are my top 3 brands that make premium CBD oil for different types of consumers.

1. Royal CBD

Get 15% off all Royal CBD products. Use code “CFAH” at checkout.

Pros:

  • Royal CBD comes from organic hemp grown on American farms
  • The company employs CO2 extraction so their extracts are clean and safe
  • Their CBD oil comes in three different strengths: 250 mg, 500 mg, 1000 mg, and 2500 mg
  • Up to 83.3 mg of CBD per mL
  • Hemp extract is suspended in premium MCT oil
  • Every batch of product has been tested by a third-party laboratory

Cons:

  • No vapes or vape oils available (yet)
  • The price is on the higher end, although justified

My Thoughts on Royal CBD:

Royal CBD is a premium brand that uses only high-quality ingredients in their product lineup. The company’s product range includes every basic CBD format, from sublingual drops to gummies and capsules.

The oil and capsules are full-spectrum, meaning they also contain other cannabinoids and terpenes from hemp. Gummies, on the other hand, contain 99% pure isolate.

The Royal CBD oil comes in three different potencies: 250 mg, 500 mg, 1000 mg, and 2500 mg. The strongest option gives you 83 mg of CBD/mL. I would recommend this variant for stronger symptoms. Those who need noticeably higher doses of CBD may find the weaker bottles cost-prohibitive.

If you don’t want to measure out the oil each time you need CBD, you may switch to Royal capsules. Each softgel carries 25mg of full-spectrum cannabidiol in an easy-to-swallow form.

All Royal CBD products are sent to third-party laboratories for content analysis — checking the potency of CBD as well as purity levels.

2. Gold Bee (Best Organic)

Pros:

  • Unique product selection
  • Non-GMO, Colorado grown hemp
  • Full-spectrum CBD
  • Extracted with CO2
  • Up tp to 1200 mg of CBD per bottle (40 mg/mL)
  • Sweetened with organic honey
  • Third-party lab tested for potency and purity

Cons:

  • No high-strength oils
  • Not available in-store
My Thoughts On Gold Bee:

Gold Bee specializes in all-organic CBD products, including full-spectrum CBD oil, high-potency CBD capsules, gummies, and delicious honey sticks. The company’s CBD oil is available in one potency option, packing 1200 mg of CBD per bottle.

This concentration translates into 40 mg of CBD in each milliliter. The oil has been suspended in premium-grade MCT oil and infused with natural terpenes to enhance the synergy between CBD and other compounds in hemp. There are two flavors available: natural and kiwi. The kiwi flavor is sweetened with organic honey, which only adds to the product’s value.

I’ve been taking the Gold Bee CBD oil for 30 days, using the dosage based on the recommended serving size. At first I was skeptical because I got used to higher doses in my routine — low doses could hardly calm my nervous system.

To my surprise, 1 mL a day split into two doses was enough to boost my resistance to stress and the outside stimuli. After two weeks, I slightly decreased the dosage and was still getting pretty good results. This was the first time a potency lower 1500 mg lasted more than 1 month for me.

3. CBDPure

Pros:

  • CBDPure products come from organic hemp grown in Colorado
  • The company uses CO2 extraction
  • All products are tested by 3rd-party laboratories for potency and purity
  • Available in 60 mL bottles
  • 100% Satisfaction Guaranteed program — you can send your order back within 90 days for a full refund

Cons:

  • CBDPure only sells CBD oil and capsules
  • The oil is slightly less potent than Royal CBD

My Thoughts on CBDPure:

CBDPure was established in 2016 by a group of cannabis advocates from Colorado. The company has a simple mission, which is to make premium-quality CBD oils from organic hemp.

Although CBDPure has a very narrow product range — offering only CBD oil and capsules — they seem to have perfected these products. All extracts from CBDPure are obtained using supercritical CO2 and tested in a certified laboratory for quality assurance.

The oil isn’t as potent as the one offered by Royal CBD, but if you benefit from lower doses, their 60-mL bottles will get you supplied for months to come. Their oils are a good option for people who use CBD for general health care or to ease mild symptoms.

If you’re looking for something potent, try CBDPure capsules — each softgel is infused with 25 mg of full-spectrum CBD for easier dosing and extra convenience.

CBDPure has a Satisfaction Guarantee program, so in case you ended up unsatisfied with your purchase, you can get a full refund if you send the order back within 90 days.

4. CBDistillery

Pros:

  • CBDistillery uses Colorado-grown hemp
  • Their products are available as full-spectrum or isolate
  • They have an impressive product selection
  • Each batch is sent to a 3rd-party lab for content analysis
  • Very affordable

Cons:

  • Their hemp isn’t organic

My Thoughts on CBDistillery:

CBDistillery is a company founded in Denver, Colorado. They’ve been offering high-quality CBD oil products for over 5 years now. One of the driving forces behind the brand is to manufacture CBD oil for every budget and promote research and education among consumers all over the country.

CBDistillery has many different forms of CBD, from sublingual tinctures to capsules, gummies, topicals, and vapes. Their CBD oil is available as ‘full-spectrum’ or isolate.

These oils come in two different sizes — 15 mL and 30 mL

The potency of the 15 mL bottle ranges between 150–1,000 mg of CBD. The 30 mL bottle offers from 2,500–5,000 of total CBD.

With such a wide potency range, CBDistillery oils may suit both novice and experienced consumers alike. The only downside to the company’s product range is that they’re not made with organic hemp.

However, this becomes understandable once you consider the price of CBDistillery products. The company may not sell the best CBD oil on the market, but they offer the best CBD products in this price range.

What is CBD Oil?

CBD oil is a cannabis extract with high concentrations of CBD. This product can be sourced from both marijuana and hemp, two members of the cannabis plant family.

It’s worth noting that marijuana-derived CBD oil contains higher levels of THC, the psychoactive cannabinoid responsible for getting users “high.”

CBD oil from hemp has only trace amounts of THC — typically below 0.3% — and thus can’t produce any psychoactive effects.

That’s because CBD is non-psychoactive per se.

CBD oil reportedly has a plethora of health benefits. However, the best-documented evidence thus far comes from epilepsy trials.

Does CBD Oil Work for Seizures?

The earliest studies proving the effectiveness of cannabis compounds in the treatment of convulsions came from animal research from the 1970s. The researchers analyzed the anticonvulsant properties of both THC and CBD oils, concluding that both extracts had substantial effects on mice.

Early experiments reported that the seizure activity might in part, be regulated by the endocannabinoid system — an interconnected network of cannabinoid receptors and neurotransmitters called endocannabinoids.

The Mechanism Behind the Antiepileptic Effects of CBD

The endocannabinoid system works to keep the body in a state of equilibrium, maintaining chemical balance and controlling biological functioning, from appetite to motor control, sensory perception, sleep, and inflammation.

It sends signals to various bodily systems through its chemical messengers called endocannabinoids to do this. These molecules bind to the cannabinoid receptors which occur in the brain and throughout the body. By doing so, endocannabinoids help the endocannabinoid system to maintain healthy functioning of an individual.

Once endocannabinoids have done their work, they get broken down by enzymes to prevent overaccumulation.

As a cannabinoid, CBD is almost identical in its chemical structure as endocannabinoids produced by your body. When you ingest CBD, it’s able to affect cannabinoid receptors on top of acting on several other pathways.

While scientists still don’t know exactly how CBD oil works for seizures, they’ve observed the following interactions which may explain the positive effects:

  1. Endocannabinoids are neuroprotectants, lowering the risk of seizures caused by neurotoxicity. When a person ingests CBD, they introduce more cannabinoids to their system—potentially improving the performance of the endocannabinoid system with their neuroprotective properties.
  2. The endocannabinoid system also modulates neuroexcitation, a process that may trigger seizures. A properly functioning endocannabinoid system, bolstered by additional cannabinoids from CBD oil, may prevent the overexcitation of neurons.
  3. CBD is also an anti-inflammatory agent. Seizures may be triggered, or their frequency may be increased by brain inflammation. By curbing neuroinflammation, CBD may reduce both the severity and frequency of seizure attacks.

Now, let’s elaborate on the scientific findings regarding the antiepileptic properties of CBD oil.

What the Research Says

The majority of specific case studies from the late 1990s, and the early 2000s focused on the effect of THC/CBD solutions on epilepsy. Due to the psychoactive nature of THC, the eyes of modern medicine turned to CBD.

In June 2018, the FDA approved the first CBD-based drug. The oral spray, called Epidiolex, contains 99% pure CBD. It’s used for treatment-resistant forms of childhood epilepsy — such as Lennox-Gastaut syndrome and Dravet syndrome.

Both diseases begin during early childhood and often lead to delayed or poor development of the child’s motor skills, language, intellectual aptitude, and the ability to communicate with others.

Before receiving the FDA’s approval, Epidiolex went through three randomized, double-blind, placebo-controlled clinical trials examining 516 patients with either syndrome. When administered along with other medications, Epidiolex successfully reduced the participant’s frequency of seizures compared to the placebo group. Besides, CBD improved other associated symptoms for the participants, such as sleep and anxiety.

Currently, Epidiolex can be officially used to treat these two types of epilepsy. However, recent research suggests that CBD may help relieve other forms of this disease as well.

For instance, a 2015 study analyzing the reports from Epidiolex patients from 11 epilepsy centers across the country showed that the frequency of seizures decreased by 36.5% after a 13-week treatment.

All subjects had severe, childhood-onset forms of epilepsy, including Lennox-Gastaut syndrome and Dravet Syndrome. The researchers started with a dose of 2–5 mg/kg per day and gradually increased it to 25–50 mg/kg per day.

Can You Develop a Tolerance to CBD Oil for Seizures?

People who have treatment-resistant epilepsy tend to experience a “honeymoon” period upon switching to a new therapy. In other words, they stop feeling the effects of their new treatment after a few months. In late 2018, scientists observed that the same pattern might apply to CBD treatment.

The study examined nearly 100 patients, of which about one-third developed a tolerance to CBD. The tolerance showed up about seven months after they began the therapy. From then on, they had to increase the dose to maintain the effects. When the dose was higher, nearly half of the examined sample experienced their previous response level.

The good news, though, is that for two-thirds of participants, the CBD proved effective in the long run.

How to Use CBD Oil for Epilepsy

CBD can take many forms. Epidiolex, the only approved CBD treatment for epilepsy, is an oral solution containing 99% pure CBD.

If you want to use CBD in a more natural form to see how it works for your symptoms, you may try the following formats:

  • Sublingual drops: The most common form of CBD. The drops are administered via a dropper under the tongue, where they get absorbed through special membranes into the bloodstream. Sublingual drops provide the most consistent blood absorption rates according to studies.
  • Capsules: CBD capsules are sold as pills and softgels. You just swallow them like any other pill. They offer a fixed dose of CBD in each serving, which makes dosing easier than sublingual drops, not to mention you can avoid any natural hemp taste.
  • Vape oils: this form of CBD is inhaled through a vaporizer or vape pen. Many people prefer vape oils over other products because they find the act of inhalation relaxing, and they like the flavoring of vape oils. But most importantly, vape oils deliver more CBD to your system than any other consumption method.

CBD Oil Dosage for Epilepsy & Seizures

The dose-finding process will vary between patients. As with every new substance, a conservative approach and slow dosage increase will minimize the chance of severe side effects and leave room for adjusting the dose from the starting point.

For each individual, the optimal CBD dosage will depend on the following:

  • CBD concentration
  • Cannabinoid spectrum
  • Route of administration
  • Weight
  • Age
  • Metabolism
  • Lifestyle choices
  • Medications the patient is already taking

Dr. Karen Keough, Chief Medical Officer at Compassionate Cultivation, created general dosage guidelines for dosing CBD oil to both adults and children who have epilepsy.

Dosing Recommendations for Children

Depending on the severity of symptoms, children may go through low-dose initiation and high-dose initiation.

Low-Dose Initiation instructions:

  • Start with 0.25 mg/lb/day
  • The minimum dose is 10 mg
  • Target dose ranges between 1–5 mg/lb/day. Higher doses are tolerated but at the cost of some mild side effects, such as dry mouth, dry eyes, low blood pressure, sedation, and dizziness.
  • Average dose is 1–3 mg/lb/day
  • Increase the dose every 1–2 weeks by 0.5 mg/lb/day, topping to the nearest 10 mg as long as there are no side effects.

High-Dose Initiation in Children:

  • Start with 0.5mg/lbs/day
  • Target dose ranges between 1–5 mg/lb/day
  • Average dose is 1-3 mg/lb/day
  • Increase the dose every 1–2 weeks by 0.5 mg/lb/day and monitor the effects
  • If side-effects occur, leave more time between dose increases and go up more gradually

Dosing Recommendations for Adults

Considering the factors above, such as body weight and metabolism, adults with epilepsy need more CBD in their regime than children. Use the following guidelines to reach an effective dose:

Low CBD dose in adults:

  • Start with 25 mg twice daily
  • Go up by 25 mg per dose every 1–2 weeks
  • Target dose ranges between 100–300 mg twice a day if no side effects are observed. Clinical trials have utilized doses as high as 1,500 mg of CBD daily, but such high doses might not be necessary to achieve seizure relief in most patients

High CBD dose in adults:

  • Start with 50 mg twice daily
  • Go up every 1–2 weeks by 50 mg/dose
  • Target dose ranges between 200–500 mg twice a day if tolerated. You may stop sooner if seizures are gone to prevent further dosage increase and possible side effects.

Where to Find CBD Oil for Sale for Epilepsy & Seizures

CBD oil is available both in cannabis dispensaries and online retail stores. Dispensaries give you access to a wide range of cannabis products, including CBD oil from hemp. However, these places may not always carry the best products, and the bottles have probably spent some time on the shelves before being sold so that they may lose potency over time due to poor storage.

That’s why I buy my CBD oil online. The majority of CBD stuff is sold this way, so you have more options to choose from. Also, you can verify the reputation of your potential vendor with the help of online research. Read user reviews, check for third-party lab reports, and learn how your company sources its CBD to make sure you’re getting a clean and potent product.

The delivery time for CBD oil is usually 2–3 business days. But in my opinion, it’s worth it to wait a few days more to get a high-quality product for a good price — CBD oil ordered online is usually less expensive than what you see in a dispensary.

Using CBD Oil for Seizures: Will It Help?

Cannabinoids have many proven beneficial effects on health, particularly in the treatment and management of epileptic seizures. Epilepsy is currently the only FDA-approved condition for treatment with CBD — although this approval doesn’t apply to hemp-derived CBD oil.

Still, if you want to try CBD oil for better management of your symptoms, I hope this guide has helped you understand how to use it to get the most out of its benefits. Just remember to start low and slow with the dosage.

But above all, consult with your doctor before purchasing any CBD product — just to make sure it won’t negatively interfere with any medications you’re taking.

Do you know any examples of people who successfully reduced the frequency of their seizures with CBD oil? Share your stories in the comments below!

References:

  1. Filloux, F. M. (2016). Cannabinoids for Pediatric Epilepsy? Up in Smoke or Real Science? Translational Pediatrics, 4(4), 271–282.
  2. Perucca, E. (2017). Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last? Journal of Epilepsy Research, 7(2), 61–76.
  3. Devinsky, O. et al. (2016). Cannabidiol in Patients With Treatment-Resistant Epilepsy: An Open-Label Interventional Trial. The Lancet: Neurology, 15(3), 270–278.
  4. Mannila, J., Jarvinen, T., Jarvinen, K., Jarho, P. (2007). Precipitation Complexation Method Produces Cannabidiol/Beta-Cyclodextrin Inclusion Complex Suitable for Sublingual Administration of Cannabidiol. Journal of Pharmaceutical Sciences, 96(2), 312–9.
  5. Millar, S.A., Stone, N.L., Yates, A.S. & O’Sullivan, S.E. (2018) A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans. Frontiers in Pharmacology, 9, 1365.
Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

Leave a comment Cancel reply

Your email address will not be published. Required fields are marked *

Save my name, email, and website in this browser for the next time I comment.

13 Best CBD Oils for Seizures

This article contains affiliate links to products. We may receive a commission for purchases made through these links.

If you or someone you know has epilepsy, it’s likely that you have been looking for a natural way to control seizures. In this article, we will explore some of the best CBD oils available right now for treating epilepsy and seizure disorders.

CBD (cannabidiol) is one of many chemical compounds found in cannabis plants. It does not produce any psychoactive effects so it can be safely used by children, adults, and pets without fear of getting high or experiencing side effects.

These benefits aside, there are also numerous studies that show that CBD oil may help with anxiety and depression as well as chronic pain relief without the side effects associated with prescription medications like opioids.

As such, CBD oil is quickly becoming an ideal supplement for those who want to live a healthier and happier life.

What is CBD?

CBD, or cannabidiol, is one of the many active compounds found in cannabis plants. Although it is not psychoactive like THC (tetrahydrocannabinol), CBD has valuable health benefits that have recently attracted the attention of medical professionals around the world for treating conditions that were once deemed untreatable.

The reason why CBD is non-intoxicating is because it does not affect the same pathways as THC. This makes it a much better option for those who are looking to achieve therapeutic benefits without experiencing mind-altering effects that may interfere with their day-to-day tasks.

While research has not yet fully determined all of the health benefits of CBD, studies have shown that this compound is extremely safe, even at high dosages. Even so, most people who are looking for the benefits of CBD oil may not be aware of the best ways to use it for maximum therapeutic benefits.

Does CBD Oil Work for Seizures?

For those who are not aware, there are actually several types of seizures, all of which can be treated using CBD oil. The most well-known form is epilepsy, which occurs in the brain.

Based on some studies, we’ve learned that CBD does not act on the same pathways as THC, it is actually one of the most ideal options for treating seizures. CBD helps calm electrical and chemical activity in the brain to promote healthy neurological development, which helps prevent seizure attacks.

Of course, you should always talk to your doctor before adding CBD to your regimen. But whether you are looking for a safe alternative option or need relief from epilepsy, CBD oil has been found to be extremely effective as a treatment option with little to no side effects.

Are There Side Effects of CBD Oils?

CBD is no longer viewed as a dangerous and addictive drug like it once was many years ago. Today’s CBD products are non-intoxicating and comprised of natural ingredients that actually work with your endocannabinoid system instead of against it.

Even so, some people who are new to CBD oil may experience mild side effects like fatigue, dry mouth, and changes in appetite. If you notice any of these side effects when using CBD for seizures, it is best to only use the recommended dosage on your product’s packaging so you can adjust accordingly.

Today we’re sharing more about CBD oils for seizures to help you find maximum relief with a more natural product.