CBD for chronic pain: The science doesn’t match the marketing
If you ask health care providers about the most challenging condition to treat, chronic pain is mentioned frequently. By its nature, chronic pain is a complex and multidimensional experience. Pain perception is affected by our unique biology, our mood, our social environment, and past experiences. If you or a loved one is suffering from chronic pain, you already know the heavy burden.
People are looking for novel, nonaddictive ways to treat pain
Given the ongoing challenges of chronic pain management coupled with the consequences of the opioid epidemic, pain management practitioners and their patients are searching for effective and safer alternatives to opioids to alleviate pain. With the legalization of marijuana in many states and resulting cultural acceptance of this drug for recreational and medical use, there has been an increased interest in using cannabis for a myriad of medical problems, including pain.
Cannabis (most commonly obtained from the Cannabis indica and Cannabis sativa plants) has three major components: cannabinoids, terpenoids, and flavonoids. While there are over a hundred different cannabinoids, the two major components are tetrahydrocannabional (THC) and cannabidiol (CBD). Historically more attention has been paid to the psychoactive (euphoric “getting high”) component of the cannabis plant, THC; there have been fewer scientific studies on the medical use of CBD, a non-psychoactive component of the plant.
What’s the thinking behind using cannabis for chronic pain?
CBD is emerging as a promising pharmaceutical agent to treat pain, inflammation, seizures, and anxiety without the psychoactive effects of THC. Our understanding of the role of CBD in pain management continues to evolve, and evidence from animal studies has shown that CBD exerts its pain-relieving effects through its various interactions and modulation of the endocannabinoid, inflammatory, and nociceptive (pain sensing) systems. The endocannabinoid system consists of cannabinoid receptors that interact with our own naturally occurring cannabinoids. This system is involved in regulating many functions in the body, including metabolism and appetite, mood and anxiety, and pain perception.
What’s the research that CBD works in humans?
Given its promising results in animal models, along with its relative safety, non-psychoactive properties, and low potential for abuse, CBD is an attractive candidate to relieve pain. Unfortunately, there is a lack of human studies about the effectiveness of CBD. However, there is an abundance of commercial advertisements about the magical effects of CBD, and it is frequently presented as a cure-it-all potion that will treat everything including diabetes, depression, cancer, chronic pain, and even your dog’s anxiety!
So far, pharmaceutical CBD is only approved by the FDA as adjunct therapy for the treatment of a special and rare form of epilepsy. Currently, CBD alone is not approved for treatment of pain in the United States. But a combination medication (that contains both THC and CBD in a 1:1 ratio) was approved by Health Canada for prescription for certain types of pain, specifically central neuropathic pain in multiple sclerosis, and the treatment of cancer pain unresponsive to optimized opioid therapy. There is currently no high-quality research study that supports the use of CBD alone for the treatment of pain.
Why is CBD presented to the public this way, when it is not without risks?
Given the rapid change in the legality of cannabis coupled with the increased appetite for something new, and driven by unprecedented profit margins, the advertising for cannabinoids in general and CBD in particular has gone wild. The FDA is very clear that it is illegal to market CBD by adding it to a food or labeling it as a dietary supplement. And it warns the public about its potential side effects, as it’s often advertised in a way that may lead people to mistakenly believe using CBD “can’t hurt.” CBD can cause liver injury, and can affect the male reproductive system (as demonstrated in laboratory animal studies).
Most importantly, CBD can interact with other important medications like blood thinners, heart medications, and immunosuppressants (medications given after organ transplantation), potentially changing the levels of these important medications in the blood and leading to catastrophic results, including death. Also, more information needs to be gathered about its safety in special populations such as the elderly, children, those who are immunocompromised, and pregnant and breastfeeding women.
Many of the CBD products on the market are unregulated
In fact, the FDA has issued several warning letters to companies and individuals that market unapproved new drugs that allegedly contain CBD. The FDA has tested the chemical content of cannabinoid compounds in some of the products, and many were found to not contain the levels of CBD the manufacturers had claimed they contain.
Beware of powerful testimonials
Finally, there is anecdotal wisdom, when experiences by patients and health professionals have positive results. While the experience or medication could be beneficial, that doesn’t mean it is going to work for everyone. That’s because each and every person is unique, and what works perfectly for one patient could have no effect on another patient. This is especially true for pain, where many other factors (our mood and stress level, our environment and other medical conditions, and our previous experiences) can affect the perception of pain. Please be careful, and keep in mind that some of these incredible-sounding testimonials are merely marketing materials meant to lure consumers to buy more products, as the CBD market is expected to hit $20 billion by 2024.
The bottom line: Don’t make CBD your first or only choice for pain relief
If you or someone close to you is considering trying CBD, I would recommend Dr. Robert Shmerling’s advice about the dos and don’ts in choosing an appropriate product. Until there is high-quality scientific evidence in humans, it is difficult to make a recommendation for the regular use of CBD in chronic pain management.
About the Author
Shafik Boyaji, MD , Contributor
Dr. Boyaji earned his medical degree from University of Aleppo, Syria. He completed an Internal Medicine residency at Michigan State University and an Anesthesiology residency at the Brigham and Women’s Hospital. Currently he is in fellowship … See Full Bio
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Ive been in persistent ache for 10 years. I’ve been the usage of Kratom and marijuana to deal with the ache. I would not be alive these days with out the kratom. I became the usage of hydrocodone which became a terrible enjoy mentally and physically. Recently my canine evolved a hip trouble wherein she should not walk. The groomer started out making use of cbd oil and in quick time she became lots higher It’s an absolute miracle. Marijuana is a plant now no longer a drug and additionally hemp has come to be a superfood. Marijuana became maximum possibly made unlawful to guard the earnings of pharma.
CBD Oil for Muscle Spasms: Is Cannabidiol an Effective Treatment?
CBD is a great way to relieve the symptoms of muscle spasms.
In this article, we will be looking at the best CBD for muscle spasms.
We’ll cover how it works, what dose to use, what forms work best, and what side-effects to watch out for.
What Are Muscle Spasms?
Muscle spasms, also known as muscle cramps, are the result of involuntary contractions. Muscle spasms can become an issue if they cannot be relaxed naturally.
Anyone can suffer from muscle spasms with the most common muscle groups being the thighs, claws, arms, hands, and feet.
Pain levels range from mild annoyance to severe pain.
When you suffer from muscle spasms, the affected muscle may feel harder and look distorted. This is due to the involuntary contractions. These spasms can last a few seconds to 10 minutes or more.
Muscle spasms can happen at any time to people of all ages. When you’re exercising, sitting still, sleeping, or even walking to the shop you can experience these cramps.
Some people suffer more than others. People with diabetes, anemia, MS, spinal injuries, or kidney disease can suffer more from this issue than people in good health.
What Causes Muscle Spasms?
Whether you suffer from the above ailments or not, there are a few common issues that can cause muscle spasms. See the list below.
- Insufficient stretching before physical activity
- Muscle fatigue
- Physical activity in hot climates
- Electrolyte imbalances
- Too much caffeine
- Exhaustion and lack of sleep
- Certain prescription medications
Methods to Reduce or Prevent Muscle Spasms
As well as using CBD for muscle spasms there are some ways you can reduce or prevent the spasms entirely. Of course, if you suffer from a disease, illness, or take medication that causes muscle spasms, these pointers may not help.
If you regularly suffer from muscle spasms, then implementing a few of the points below may help you:
- Stay hydrated
- Make sure to stretch before strenuous activity
- Try and lower your stress levels (CBD is great for this)
- Get a full 8 hours rest at night
- Take mineral supplements that include magnesium, potassium, and sodium
- If prescription meds are causing issues, speak with your doctor about alternatives
- Cut down on the caffeine
- Avoid over-exercising
Muscle Spasms & the Endocannabinoid System
The endocannabinoid system is made up of cannabinoid receptors CB1 and CB2. It’s a complex cell-signaling system that was first identified in the 1990s.
Regardless of whether you use CBD or other cannabis products, this system is part of everyone’s biology.
Endocannabinoids are cannabinoids made inside the body. They help regulate a range of functions and processes. See the list below for a few of these.
- Mood and emotion
- Immune response
In the same way that endocannabinoids interact with the body, cannabinoids from the hemp plant do as well — including CBD. They do this by interacting with CB1 and CB2 receptors.
CB1 receptors have been identified predominantly in the central nervous system (brain and spinal cord). They’ve also been found in connective tissues, the intestines, gonads, and other peripheral organs.
CB2 receptors have been identified in white blood cells, the spleen, tonsils, thymus, and lymphatic system.
CBD and other cannabinoids interact with these receptors. Studies have shown that CBD impacts receptor activity. They can interact with neurotransmitters, reduce inflammation, and aid in pain relief.
When a muscle contracts, causing cramps and spasms, it’s because of a chemical message from the central nervous system. The body’s endocannabinoid system can take care of this and reduce contractions and pain.
If the body struggles to produce enough endocannabinoids to stop these chemical signals, then muscle spasms will continue to cause discomfort.
This is where CBD comes in.
CBD interacts with the CB1 receptors in the central nervous system and effectively slows the chemical signals that are causing the spasms .
This results in muscle relaxation and fewer muscle contractions. Pain relief coincides with these effects.
Can CBD Relieve Muscle Spasms?
As mentioned in the last section, CBD interacts with the body’s endocannabinoid system to relieve muscle spasms and the pain associated with it.
CBD Relaxes the Muscles
CBD is a great muscle relaxant. Unlike painkillers, muscle relaxants work to solve the issue of muscle cramps rather than just numbing the pain that results from it.
The beauty of CBD is that it gets to the root of the problem and influences the chemical signals that cause muscle spasms (as mentioned in the last section).
Unlike spasmolytic and neuromuscular blockers, CBD has few negative side effects and works with your body’s natural functions rather than against them.
Spasmolytic muscle relaxants are particularly dangerous, especially for older people. They can increase heart rate, and blood pressure, and can be incredibly addictive as this type of medication is part of the opioid group.
CBD certainly isn’t dangerous, doesn’t increase the heart rate, and there are no documented cases of addiction to the cannabinoid.
CBD Reduces Stress
CBD helps reduce stress which can be a trigger for muscle spasms.
There is a lot to say about CBD reducing stress and anxiety . The cannabinoid is commonly used to help these problems by people all over the world.
Although stress is not directly related to muscle spasms, it can be one of the reasons you’re experiencing these issues.
It’s important to address the cause of an issue. If stress is giving you muscle spasms, you should work toward reducing or eliminating it completely. Lowering stress levels using CBD could be a great long-term treatment if stress is the cause.
CBD Can Aid Sleep
Lack of sleep and exhaustion can cause muscles to spasm. CBD can help you get to sleep faster and achieve a full nights’ rest.
If you struggle with sleep, high-doses of CBD before bedtime can help you doze off into a deep sleep. Stress is often the cause of lack of sleep, so both factors go hand in hand.
Some research shows that CBD can have an effect on cortisol levels .
Cortisol regulates your sleep cycle. Some people (particularly insomnia sufferers) have high levels of cortisol at night which keeps them awake.
Taking high doses of CBD at night can decrease cortisol levels, getting you to sleep easier and faster.
CBD Aids Muscle Recovery
CBD is believed to aid in muscle recovery . Many athletes and fitness fanatics use CBD as it can speed up the muscle recovery process.
If you’re experiencing muscle spasms after exercise or excessive physical activity, this benefit will help you get instant and long-term relief.
During strenuous exercise, the muscles tear and rebuild during the recovery period. During this period some people experience cramping and spasms. If you can recover more efficiently you will experience less discomfort.
How Much CBD to Take for Muscle Spasms?
High-potency CBD oil is the best treatment for muscle spasms.
How much you take will depend on you and how your body reacts to the CBD. If you’ve never used CBD before it’s best to start small and work your way up.
The dosage needed to stop muscle spasms will vary from person to person, so a bit of self-experimentation is needed to find your balance. Steadily increase your dosages until you get the effect you’re looking for.
Oils are the easiest way to find out how many milligrams of CBD you need to control muscle spasms. You can adjust the dosage by increasing or decreasing the drops of oil taken.
Final Thoughts: Does CBD Work for Muscle Spasms?
CBD is a great way to reduce muscle spasms and pain you may have as a result of them. Unlike other muscle relaxants and painkillers, CBD has few negative effects on your body and is a natural product.
As well as solving the problem directly, CBD has a number of benefits that work together to reduce muscle spasms for the long-term.
If you got to the end of this read, you’ll know exactly how CBD can help muscle spasms and what to look for when it comes time to purchase a treatment.
If you have any questions about CBD and muscle spasms, please comment down below.
Thanks for reading.
References Used in This Article
- Shenglong Zou and Ujendra Kumar. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular science,19(3): 833.
- Esther M. Blessing, Maria M. Steenkamp, Jorge Manzanares, and Charles R. Marmar. (2015). Cannabidiol as a Potential Treatment for Anxiety Disorders. Springer Neurotherapeutics, 12(4): 825–836.
- Scott Shannon, Nicole Lewis, Heather Lee, and Shannon Hughes. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente Journal, 23: 18-041.
- Danielle McCartney, Melissa J. Benson, Ben Desbrow, Christopher Irwin, Anastasia Suraev, and Iain S. McGregor. (2020). Cannabidiol and Sports Performance: a Narrative Review of Relevant Evidence and Recommendations for Future Research. Springer Sports Medicine-Open, 6: 27.
Livvy is a registered nurse (RN) and board-certified nurse midwife (CNM) in the state of New Jersey. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. This gave her the opportunity to spend more time writing articles on all topics related to pregnancy and prenatal care.
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