Posted on

Cbd oil for esophageal spasms

Can CBD Treat GERD and Acid Reflux?

Did you know CBD oil could help with GERD and acid reflux?

Have you ever experienced heartburn after eating, especially after having spicy foods? You are not alone. Statistics show that 1 in 10 Americans experience Gastroesophageal Reflux Disease (GERD), which is closely related to the symptoms of heartburn. If you are like most people, you’ve probably tried over-the-counter medications without much success and may be looking for a more natural and healthier approach. You may have wondered can CBD treat GERD and Acid Reflux?

CBD oil therapy can be an effective treatment for many health issues, including gastrointestinal problems such as acid reflux disease.

What Exactly is GERD?

Gastroesophageal Reflux Disease (GERD) happens when the stomach acid content frequently flows back up into the esophagus — the tube connecting the mouth and the stomach. This acid reflux causes irritation in the lining of your esophagus.

When the digestion is normal, the the lower esophageal sphincter (LES) relaxes so that the food can enter the stomach. It then narrows to prevent both the stomach acid and food from coming back up into the esophagus.

GERD occurs when the lower esophageal sphincter is weak or doesn’t relax appropriately, allowing the stomach contents to back up into the esophageal. The heartburn that you experience is as a result of discomfort caused by reflux of the stomach contents to the esophagus.

There are a few ways to treat GERD. One is to avoid foods that you know make it worse, especially known culprits such as alcohol and caffeine. Another way to treat GERD is with prescription medication or over-the-counter medicines. However, many of these prescriptions can have adverse side effects.

There is another method to try — CBD oil.

Can CBD Treat GERD and Acid Reflux?

Every human body has an endocannabinoid system (ECS), which has many functions including sensations, memory, pain perception, etc. Specifically, the ECS exhibits anti-secretory effects on gastric acid as well as mitigates inflammation and damage of the mucous membranes that most GERD patients experience.

When the CBD reacts with the endocannabinoid system, it reduces the secretion of acids that would otherwise cause actual burn when dealing with the symptoms of GERD.

Research done by a Swedish scientist suggests that when certain cannabinoid receptors are activated, they produce pain-relieving effects, including in the gastrointestinal tract. This shows that cannabinoids found in medical marijuana can play an essential role in treating acid reflux disease.

CBD interacts with the soft muscle tissues of the gastrointestinal system. It soothes and calms the peristalsis that moves waste and food. It also modulates the LES to minimize spasms and irregular functions.

WHO is Looking at the Benefits of CBD

Furthermore, in a 2018 report, the World Health Organization (WHO) through its Expert Committee on Drug Dependence said that they were exploring CBD for its potential anti-epileptic, anxiolytic, neuroprotective, anti-psychotic, anti-inflammatory, anti-tumor, anti-asthmatic and analgesic properties.

If you’ve decided to try CBD to treat GERD, it’s advisable to use CBD oil sublingually with tinctures or capsules as opposed to smoking, which can lead to further irritation.

WO2015198209A1 – Use of cannabis for the treatment of achalasia – Google Patents

Publication number WO2015198209A1 WO2015198209A1 PCT/IB2015/054684 IB2015054684W WO2015198209A1 WO 2015198209 A1 WO2015198209 A1 WO 2015198209A1 IB 2015054684 W IB2015054684 W IB 2015054684W WO 2015198209 A1 WO2015198209 A1 WO 2015198209A1 Authority WO WIPO (PCT) Prior art keywords thc cbd achalasia treatment food Prior art date 2014-06-23 Application number PCT/IB2015/054684 Other languages French ( fr ) Inventor Amandine LUQUIENS Original Assignee Assistance Publique – Hopitaux De Paris Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2014-06-23 Filing date 2015-06-23 Publication date 2015-12-30 2014-06-23 Priority to FR1455779 priority Critical 2014-06-23 Priority to FR1455779A priority patent/FR3022457B1/en 2015-06-23 Application filed by Assistance Publique – Hopitaux De Paris filed Critical Assistance Publique – Hopitaux De Paris 2015-12-30 Publication of WO2015198209A1 publication Critical patent/WO2015198209A1/en

Links

  • Espacenet
  • Global Dossier
  • PatentScope
  • Discuss
  • 208000000289 Esophageal Achalasia Diseases 0.000 title claims abstract description 21
  • 206010030136 Oesophageal achalasia Diseases 0.000 title claims abstract description 21
  • 201000000621 achalasia Diseases 0.000 title claims abstract description 21
  • 241000218236 Cannabis Species 0.000 title description 11
  • QHMBSVQNZZTUGM-ZWKOTPCHSA-N Cannabidiol Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 196.5,189.1 L 193.4,184.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 193.4,184.8 L 190.3,180.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 190.3,180.4 L 161.2,186.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 184.6,175.6 L 164.3,180.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-12 atom-1' d='M 199.2,152.0 L 190.3,180.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 161.2,186.9 L 141.1,165.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 141.1,165.0 L 112.0,171.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 141.1,165.0 L 150.0,136.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 148.1,162.5 L 154.3,142.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 112.0,171.5 L 91.9,149.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 91.9,149.6 L 62.8,156.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 62.8,156.1 L 42.7,134.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 42.7,134.1 L 13.6,140.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 150.0,136.6 L 179.1,130.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 179.1,130.1 L 181.6,122.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 181.6,122.1 L 184.1,114.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 179.1,130.1 L 199.2,152.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 177.7,137.4 L 191.8,152.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 222.3,146.2 L 222.6,147.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 216.4,147.0 L 216.9,149.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 210.4,147.7 L 211.2,151.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 204.5,148.4 L 205.5,153.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 198.6,149.1 L 199.8,154.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 228.3,145.5 L 248.4,167.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-22 atom-13' d='M 237.2,117.1 L 228.3,145.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 248.4,167.4 L 236.7,195.0 L 242.3,196.7 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-17 atom-14 atom-18' d='M 248.4,167.4 L 277.5,161.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 239.5,195.9 L 259.6,217.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 238.9,194.2 L 218.4,201.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 240.1,197.5 L 219.6,204.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 277.5,161.0 L 286.4,132.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 286.4,132.6 L 266.2,110.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 266.2,110.6 L 275.1,82.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 266.2,110.6 L 237.2,117.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 263.2,117.4 L 242.8,122.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='199.3' y='204.0' class='atom-0' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='207.6' y='204.0' class='atom-0' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='184.4' y='107.6' class='atom-11' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='192.6' y='107.6' class='atom-11' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 55.6,53.7 L 54.5,52.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 54.5,52.1 L 53.4,50.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 53.4,50.6 L 45.2,52.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 51.8,49.2 L 46.1,50.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-12 atom-1' d='M 55.9,42.6 L 53.4,50.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 45.2,52.5 L 39.5,46.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 39.5,46.2 L 31.2,48.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 39.5,46.2 L 42.0,38.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 41.5,45.5 L 43.2,39.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 31.2,48.1 L 25.5,41.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 25.5,41.9 L 17.3,43.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 17.3,43.7 L 11.6,37.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 11.6,37.5 L 3.4,39.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 42.0,38.2 L 50.2,36.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 50.2,36.4 L 51.0,33.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 51.0,33.9 L 51.7,31.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 50.2,36.4 L 55.9,42.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 49.8,38.4 L 53.8,42.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 61.4,41.1 L 61.5,41.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 58.6,41.4 L 58.8,42.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 55.8,41.7 L 56.1,43.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 64.2,40.7 L 69.9,46.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-22 atom-13' d='M 66.7,32.7 L 64.2,40.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 69.9,46.9 L 66.6,54.7 L 68.2,55.2 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-17 atom-14 atom-18' d='M 69.9,46.9 L 78.1,45.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 67.4,55.0 L 73.1,61.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 67.2,54.5 L 61.4,56.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 67.5,55.5 L 61.7,57.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 78.1,45.1 L 80.6,37.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 80.6,37.1 L 74.9,30.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 74.9,30.8 L 77.5,22.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 74.9,30.8 L 66.7,32.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 74.1,32.8 L 68.3,34.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='55.2' y='58.6' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='59.3' y='58.6' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='51.0' y='31.3' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='55.1' y='31.3' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
</svg>
 OC1=CC(CCCCC)=CC(O)=C1[[email protected]]1[[email protected]](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-ZWKOTPCHSA-N 0.000 claims abstract description 33
  • 229950011318 Cannabidiol Drugs 0.000 claims abstract description 33
  • QHMBSVQNZZTUGM-MSOLQXFVSA-N Cannabidiol Natural products data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 196.5,189.1 L 193.4,184.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 193.4,184.8 L 190.3,180.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 190.3,180.4 L 161.2,186.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 184.6,175.6 L 164.3,180.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-12 atom-1' d='M 199.2,152.0 L 190.3,180.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 161.2,186.9 L 141.1,165.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 141.1,165.0 L 112.0,171.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 141.1,165.0 L 150.0,136.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 148.1,162.5 L 154.3,142.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 112.0,171.5 L 91.9,149.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 91.9,149.6 L 62.8,156.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 62.8,156.1 L 42.7,134.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 42.7,134.1 L 13.6,140.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 150.0,136.6 L 179.1,130.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 179.1,130.1 L 181.6,122.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 181.6,122.1 L 184.1,114.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 179.1,130.1 L 199.2,152.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 177.7,137.4 L 191.8,152.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 228.3,145.5 L 198.6,149.1 L 199.8,154.9 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-13 atom-13 atom-14' d='M 228.3,145.5 L 248.4,167.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-22 atom-13' d='M 237.2,117.1 L 228.3,145.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 246.1,172.9 L 247.2,173.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 243.7,178.5 L 246.0,179.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 241.4,184.0 L 244.8,185.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 239.0,189.5 L 243.5,190.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 236.7,195.0 L 242.3,196.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-14 atom-18' d='M 248.4,167.4 L 277.5,161.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 239.5,195.9 L 259.6,217.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 238.9,194.2 L 218.4,201.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 240.1,197.5 L 219.6,204.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 277.5,161.0 L 286.4,132.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 286.4,132.6 L 266.2,110.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 266.2,110.6 L 275.1,82.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 266.2,110.6 L 237.2,117.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 263.2,117.4 L 242.8,122.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='199.3' y='204.0' class='atom-0' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='207.6' y='204.0' class='atom-0' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='184.4' y='107.6' class='atom-11' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='192.6' y='107.6' class='atom-11' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 55.6,53.7 L 54.5,52.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 54.5,52.1 L 53.4,50.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 53.4,50.6 L 45.2,52.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 51.8,49.2 L 46.1,50.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-12 atom-1' d='M 55.9,42.6 L 53.4,50.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 45.2,52.5 L 39.5,46.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 39.5,46.2 L 31.2,48.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 39.5,46.2 L 42.0,38.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 41.5,45.5 L 43.2,39.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 31.2,48.1 L 25.5,41.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 25.5,41.9 L 17.3,43.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 17.3,43.7 L 11.6,37.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 11.6,37.5 L 3.4,39.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 42.0,38.2 L 50.2,36.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 50.2,36.4 L 51.0,33.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 51.0,33.9 L 51.7,31.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 50.2,36.4 L 55.9,42.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 49.8,38.4 L 53.8,42.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-13 atom-12' d='M 64.2,40.7 L 55.8,41.7 L 56.1,43.4 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-13 atom-13 atom-14' d='M 64.2,40.7 L 69.9,46.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-22 atom-13' d='M 66.7,32.7 L 64.2,40.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 68.8,49.5 L 69.3,49.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 67.7,52.1 L 68.7,52.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 66.6,54.7 L 68.2,55.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-14 atom-18' d='M 69.9,46.9 L 78.1,45.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 67.4,55.0 L 73.1,61.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 67.2,54.5 L 61.4,56.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 67.5,55.5 L 61.7,57.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 78.1,45.1 L 80.6,37.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 80.6,37.1 L 74.9,30.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 74.9,30.8 L 77.5,22.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 74.9,30.8 L 66.7,32.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 74.1,32.8 L 68.3,34.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='55.2' y='58.6' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='59.3' y='58.6' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='51.0' y='31.3' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='55.1' y='31.3' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
</svg>
 OC1=CC(CCCCC)=CC(O)=C1[[email protected]@H]1[[email protected]@H](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-MSOLQXFVSA-N 0.000 claims abstract description 33
  • 239000000203 mixture Substances 0.000 claims description 14
  • 235000013305 food Nutrition 0.000 claims description 12
  • 208000000264 Deglutition Disorders Diseases 0.000 claims description 8
  • 206010013950 Dysphagia Diseases 0.000 claims description 8
  • 210000003238 Esophagus Anatomy 0.000 claims description 8
  • 206010067171 Regurgitation Diseases 0.000 claims description 8
  • 201000010099 disease Diseases 0.000 claims description 8
  • 206010008479 Chest pain Diseases 0.000 claims description 6
  • 210000000111 Esophageal Sphincter, Lower Anatomy 0.000 claims description 6
  • 230000004580 weight loss Effects 0.000 claims description 6
  • 239000008194 pharmaceutical composition Substances 0.000 claims description 5
  • 210000000214 Mouth Anatomy 0.000 claims description 4
  • 210000003800 Pharynx Anatomy 0.000 claims description 4
  • 206010020852 Hypertonia Diseases 0.000 claims description 3
  • 239000000819 hypertonic solution Substances 0.000 claims description 3
  • 239000002253 acid Substances 0.000 claims 2
  • 239000003937 drug carrier Substances 0.000 claims 1
  • 235000015097 nutrients Nutrition 0.000 claims 1
  • 230000035807 sensation Effects 0.000 claims 1
  • CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 63.4,186.1 L 34.6,193.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 57.6,181.4 L 37.4,186.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-22 atom-0' d='M 71.3,157.3 L 63.4,186.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 34.6,193.6 L 26.7,222.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-1 atom-3' d='M 34.6,193.6 L 13.6,172.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 13.6,172.4 L 21.5,143.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 21.5,143.6 L 50.4,136.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 50.4,136.1 L 58.3,107.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-22 atom-5' d='M 71.3,157.3 L 50.4,136.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-5 atom-23' d='M 46.2,131.5 L 45.0,133.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-5 atom-23' d='M 42.0,127.0 L 39.6,130.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-5 atom-23' d='M 37.9,122.4 L 34.2,127.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 58.3,107.3 L 55.9,77.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-6 atom-8' d='M 58.3,107.3 L 29.2,101.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-6 atom-9' d='M 58.3,107.3 L 67.7,104.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-6 atom-9' d='M 67.7,104.9 L 77.0,102.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 95.7,108.4 L 101.9,114.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 101.9,114.7 L 108.1,121.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 108.1,121.0 L 136.9,113.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 113.9,125.7 L 134.1,120.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-21 atom-10' d='M 100.2,149.8 L 108.1,121.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 136.9,113.5 L 157.9,134.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 157.9,134.7 L 186.8,127.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-12 atom-18' d='M 157.9,134.7 L 150.0,163.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-12 atom-18' d='M 151.0,137.4 L 145.4,157.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 186.8,127.2 L 207.7,148.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 207.7,148.4 L 236.6,140.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 236.6,140.9 L 257.5,162.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 257.5,162.1 L 286.4,154.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 150.0,163.5 L 121.1,171.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 121.1,171.0 L 118.6,180.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 118.6,180.3 L 116.0,189.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-19 atom-21' d='M 121.1,171.0 L 100.2,149.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-19 atom-21' d='M 122.2,163.6 L 107.6,148.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 100.2,149.8 L 71.3,157.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-22 atom-24' d='M 71.3,157.3 L 81.7,172.1 L 86.0,167.9 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<text x='83.6' y='105.8' class='atom-9' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='109.7' y='205.7' class='atom-20' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='117.9' y='205.7' class='atom-20' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='23.4' y='123.6' class='atom-23' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='88.7' y='184.5' class='atom-24' style='font-size:11px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 17.5,52.2 L 9.3,54.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 15.8,50.9 L 10.1,52.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-22 atom-0' d='M 19.7,44.1 L 17.5,52.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 9.3,54.4 L 7.1,62.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-1 atom-3' d='M 9.3,54.4 L 3.4,48.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 3.4,48.3 L 5.6,40.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 5.6,40.2 L 13.8,38.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 13.8,38.1 L 16.0,29.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-22 atom-5' d='M 19.7,44.1 L 13.8,38.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-5 atom-23' d='M 12.4,36.6 L 12.1,37.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-5 atom-23' d='M 11.0,35.2 L 10.4,36.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-5 atom-23' d='M 9.7,33.7 L 8.6,35.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 16.0,29.9 L 15.3,21.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-6 atom-8' d='M 16.0,29.9 L 7.8,28.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-6 atom-9' d='M 16.0,29.9 L 19.1,29.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-6 atom-9' d='M 19.1,29.1 L 22.2,28.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 26.2,29.8 L 28.2,31.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 28.2,31.8 L 30.1,33.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 30.1,33.8 L 38.3,31.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 31.8,35.1 L 37.5,33.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-21 atom-10' d='M 27.9,41.9 L 30.1,33.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 38.3,31.7 L 44.2,37.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 44.2,37.7 L 52.4,35.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-12 atom-18' d='M 44.2,37.7 L 42.0,45.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-12 atom-18' d='M 42.3,38.4 L 40.7,44.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 52.4,35.5 L 58.3,41.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 58.3,41.5 L 66.5,39.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 66.5,39.4 L 72.5,45.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 72.5,45.4 L 80.6,43.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 42.0,45.8 L 33.8,48.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 33.8,48.0 L 33.0,51.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 33.0,51.0 L 32.1,54.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-19 atom-21' d='M 33.8,48.0 L 27.9,41.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-19 atom-21' d='M 34.1,45.9 L 30.0,41.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 27.9,41.9 L 19.7,44.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-22 atom-24' d='M 19.7,44.1 L 23.1,48.7 L 24.3,47.5 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<text x='22.4' y='30.8' class='atom-9' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='29.8' y='59.1' class='atom-20' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='33.9' y='59.1' class='atom-20' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='5.4' y='35.8' class='atom-23' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='23.9' y='53.1' class='atom-24' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 C1=C(C)CC[[email protected]]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[[email protected]@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 abstract description 20
  • 229960004242 dronabinol Drugs 0.000 abstract description 20
  • UCONUSSAWGCZMV-OEMAIJDKSA-M (6aR)-2-carboxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-olate Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 280.4,155.1 L 251.9,164.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-0 atom-6' d='M 280.4,155.1 L 286.4,125.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 251.9,164.6 L 245.9,194.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-10 atom-1' d='M 229.4,144.7 L 251.9,164.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-1 atom-26' d='M 256.5,168.9 L 257.6,167.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-1 atom-26' d='M 261.1,173.3 L 263.3,170.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-1 atom-26' d='M 265.6,177.7 L 269.0,172.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 245.9,194.0 L 250.3,223.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-2 atom-4' d='M 245.9,194.0 L 275.6,198.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-2 atom-5' d='M 245.9,194.0 L 236.7,197.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-2 atom-5' d='M 236.7,197.1 L 227.5,200.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-12 atom-5' d='M 195.0,183.6 L 201.8,189.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-12 atom-5' d='M 201.8,189.6 L 208.6,195.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 286.4,125.6 L 263.9,105.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 263.9,105.7 L 269.9,76.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-7 atom-9' d='M 263.9,105.7 L 235.4,115.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-7 atom-9' d='M 261.5,112.9 L 241.6,119.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 235.4,115.3 L 229.4,144.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 229.4,144.7 L 200.9,154.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 200.9,154.2 L 195.0,183.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 194.2,157.4 L 190.0,178.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-24 atom-11' d='M 178.5,134.3 L 200.9,154.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 195.0,183.6 L 166.5,193.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 166.5,193.1 L 144.0,173.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 167.1,185.6 L 151.4,171.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 144.0,173.2 L 115.5,182.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-14 atom-20' d='M 144.0,173.2 L 150.0,143.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 115.5,182.7 L 93.1,162.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 93.1,162.8 L 64.6,172.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-17 atom-18' d='M 64.6,172.4 L 42.1,152.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 42.1,152.5 L 13.6,162.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 150.0,143.8 L 127.5,123.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-20 atom-24' d='M 150.0,143.8 L 178.5,134.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-20 atom-24' d='M 156.2,148.1 L 176.1,141.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 127.5,123.9 L 129.2,115.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 129.2,115.5 L 130.9,107.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 126.6,121.1 L 117.4,124.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 117.4,124.1 L 108.1,127.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 128.5,126.8 L 119.3,129.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 119.3,129.8 L 110.0,132.9' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 178.5,134.3 L 180.2,125.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 180.2,125.9 L 181.9,117.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='213.8' y='209.5' class='atom-5' style='font-size:12px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='129.9' y='100.5' class='atom-22' style='font-size:12px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='138.2' y='95.7' class='atom-22' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='95.4' y='139.4' class='atom-23' style='font-size:12px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='180.9' y='110.9' class='atom-25' style='font-size:12px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='189.1' y='110.9' class='atom-25' style='font-size:12px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='273.0' y='187.6' class='atom-26' style='font-size:12px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 78.9,43.4 L 70.9,46.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-0 atom-6' d='M 78.9,43.4 L 80.6,35.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 70.9,46.1 L 69.2,54.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-10 atom-1' d='M 64.5,40.5 L 70.9,46.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-1 atom-26' d='M 72.4,47.5 L 72.7,47.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-1 atom-26' d='M 73.9,48.9 L 74.5,48.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-1 atom-26' d='M 75.4,50.3 L 76.3,48.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 69.2,54.5 L 70.4,62.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-2 atom-4' d='M 69.2,54.5 L 77.6,55.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-2 atom-5' d='M 69.2,54.5 L 66.1,55.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-2 atom-5' d='M 66.1,55.5 L 63.1,56.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-12 atom-5' d='M 54.7,51.5 L 56.9,53.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-12 atom-5' d='M 56.9,53.4 L 59.1,55.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 80.6,35.1 L 74.3,29.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 74.3,29.5 L 76.0,21.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-7 atom-9' d='M 74.3,29.5 L 66.2,32.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-7 atom-9' d='M 73.6,31.5 L 68.0,33.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 66.2,32.2 L 64.5,40.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 64.5,40.5 L 56.4,43.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 56.4,43.2 L 54.7,51.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 54.5,44.1 L 53.3,49.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-24 atom-11' d='M 50.1,37.5 L 56.4,43.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 54.7,51.5 L 46.7,54.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 46.7,54.2 L 40.3,48.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 46.8,52.1 L 42.4,48.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 40.3,48.6 L 32.2,51.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-14 atom-20' d='M 40.3,48.6 L 42.0,40.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 32.2,51.3 L 25.9,45.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 25.9,45.6 L 17.8,48.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-17 atom-18' d='M 17.8,48.3 L 11.4,42.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 11.4,42.7 L 3.4,45.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 42.0,40.2 L 35.6,34.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-20 atom-24' d='M 42.0,40.2 L 50.1,37.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-20 atom-24' d='M 43.7,41.5 L 49.4,39.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 35.6,34.6 L 36.2,32.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 36.2,32.0 L 36.7,29.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 35.4,33.8 L 32.3,34.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 32.3,34.8 L 29.3,35.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 35.9,35.4 L 32.9,36.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 32.9,36.4 L 29.8,37.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 50.1,37.5 L 50.6,35.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 50.6,35.0 L 51.1,32.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='59.3' y='60.2' class='atom-5' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='35.5' y='29.3' class='atom-22' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='39.7' y='26.9' class='atom-22' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='25.8' y='40.3' class='atom-23' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='50.0' y='32.2' class='atom-25' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='54.1' y='32.2' class='atom-25' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='76.1' y='53.9' class='atom-26' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 C([[email protected]]1C(C)(C)O2)CC(C)=CC1C1=C2C=C(CCCCC)C(C([O-])=O)=C1O UCONUSSAWGCZMV-OEMAIJDKSA-M 0.000 abstract 2
  • 239000003814 drug Substances 0.000 description 5
  • 230000001225 therapeutic Effects 0.000 description 5
  • 241000196324 Embryophyta Species 0.000 description 4
  • 229940079593 drugs Drugs 0.000 description 4
  • 230000037406 food intake Effects 0.000 description 4
  • 238000002560 therapeutic procedure Methods 0.000 description 4
  • 240000000218 Cannabis sativa Species 0.000 description 3
  • 230000000694 effects Effects 0.000 description 3
  • 238000000034 method Methods 0.000 description 3
  • SSNHGLKFJISNTR-FWUPRJFYSA-N (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol;2-[(6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 156.0,244.4 L 153.5,241.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 153.5,241.0 L 151.1,237.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 151.1,237.6 L 128.5,242.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 146.7,233.9 L 130.9,237.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-44 atom-12 atom-1' d='M 158.1,215.5 L 151.1,237.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 128.5,242.7 L 112.8,225.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 112.8,225.6 L 90.2,230.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 112.8,225.6 L 119.8,203.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 118.3,223.7 L 123.2,208.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 90.2,230.7 L 74.5,213.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 74.5,213.6 L 51.9,218.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 51.9,218.7 L 36.2,201.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 36.2,201.6 L 13.6,206.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 119.8,203.5 L 142.4,198.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 142.4,198.5 L 144.3,192.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 144.3,192.2 L 146.3,186.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 142.4,198.5 L 158.1,215.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 141.3,204.2 L 152.3,216.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 158.1,215.5 L 180.7,210.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 180.7,210.5 L 196.4,227.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-45 atom-22 atom-13' d='M 187.6,188.4 L 180.7,210.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 196.4,227.5 L 187.2,248.9 L 191.6,250.3 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-17 atom-14 atom-18' d='M 196.4,227.5 L 219.0,222.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 189.4,249.6 L 205.1,266.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 189.0,248.3 L 173.0,254.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 189.9,251.0 L 174.0,256.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 219.0,222.5 L 225.9,200.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 225.9,200.4 L 210.2,183.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 210.2,183.3 L 217.2,161.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 210.2,183.3 L 187.6,188.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 207.8,188.6 L 192.0,192.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-23 atom-24' d='M 113.2,117.6 L 90.7,123.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-23 atom-24' d='M 108.6,114.0 L 92.9,118.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-46 atom-45 atom-23' d='M 119.3,95.2 L 113.2,117.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-24 atom-25' d='M 90.7,123.4 L 84.6,145.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-26' d='M 90.7,123.4 L 74.5,106.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-26 atom-27' d='M 74.5,106.9 L 80.6,84.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-27 atom-28' d='M 80.6,84.6 L 103.0,78.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-28 atom-29' d='M 103.0,78.7 L 109.2,56.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-47 atom-45 atom-28' d='M 119.3,95.2 L 103.0,78.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-49 atom-28 atom-46' d='M 99.8,75.2 L 98.8,76.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-49 atom-28 atom-46' d='M 96.5,71.6 L 94.6,74.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-49 atom-28 atom-46' d='M 93.3,68.1 L 90.4,71.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-29 atom-30' d='M 109.2,56.4 L 107.3,33.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-29 atom-29 atom-31' d='M 109.2,56.4 L 86.5,51.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-29 atom-32' d='M 109.2,56.4 L 116.4,54.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-29 atom-32' d='M 116.4,54.5 L 123.7,52.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-32 atom-33' d='M 138.2,57.2 L 143.0,62.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-32 atom-33' d='M 143.0,62.1 L 147.8,67.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-33 atom-34' d='M 147.8,67.0 L 170.3,61.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-33 atom-34' d='M 152.4,70.6 L 168.1,66.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-48 atom-44 atom-33' d='M 141.7,89.4 L 147.8,67.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-33 atom-34 atom-35' d='M 170.3,61.2 L 186.5,77.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-34 atom-35 atom-36' d='M 186.5,77.7 L 209.0,71.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-39 atom-35 atom-41' d='M 186.5,77.7 L 180.4,100.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-39 atom-35 atom-41' d='M 181.2,79.8 L 176.9,95.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-35 atom-36 atom-37' d='M 209.0,71.8 L 225.2,88.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-36 atom-37 atom-38' d='M 225.2,88.3 L 247.7,82.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-37 atom-38 atom-39' d='M 247.7,82.4 L 263.9,98.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-38 atom-39 atom-40' d='M 263.9,98.9 L 286.4,93.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-40 atom-41 atom-42' d='M 180.4,100.0 L 158.0,105.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-41 atom-42 atom-43' d='M 158.0,105.8 L 156.0,113.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-41 atom-42 atom-43' d='M 156.0,113.1 L 154.0,120.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-42 atom-42 atom-44' d='M 158.0,105.8 L 141.7,89.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-42 atom-42 atom-44' d='M 158.8,100.1 L 147.5,88.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-43 atom-44 atom-45' d='M 141.7,89.4 L 119.3,95.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-50 atom-45 atom-47' d='M 119.3,95.2 L 127.4,106.7 L 130.7,103.4 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<text x='158.2' y='256.0' class='atom-0' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='164.6' y='256.0' class='atom-0' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='146.5' y='181.0' class='atom-11' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='152.9' y='181.0' class='atom-11' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='128.8' y='55.2' class='atom-32' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='149.1' y='132.8' class='atom-43' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='155.5' y='132.8' class='atom-43' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='82.1' y='69.0' class='atom-46' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='132.8' y='116.3' class='atom-47' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 43.7,68.8 L 43.0,67.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 43.0,67.8 L 42.3,66.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 42.3,66.8 L 35.9,68.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 41.1,65.8 L 36.6,66.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-44 atom-12 atom-1' d='M 44.3,60.6 L 42.3,66.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 35.9,68.3 L 31.5,63.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 31.5,63.4 L 25.1,64.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 31.5,63.4 L 33.4,57.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-3 atom-9' d='M 33.0,62.9 L 34.4,58.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 25.1,64.9 L 20.6,60.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 20.6,60.0 L 14.2,61.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 14.2,61.5 L 9.8,56.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 9.8,56.6 L 3.4,58.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 33.4,57.2 L 39.8,55.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 39.8,55.7 L 40.3,54.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 40.3,54.2 L 40.8,52.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 39.8,55.7 L 44.3,60.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 39.5,57.3 L 42.7,60.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 44.3,60.6 L 50.7,59.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 50.7,59.1 L 55.1,64.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-45 atom-22 atom-13' d='M 52.7,52.9 L 50.7,59.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 55.1,64.0 L 52.5,70.0 L 53.8,70.4 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-17 atom-14 atom-18' d='M 55.1,64.0 L 61.5,62.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 53.2,70.2 L 57.6,75.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 53.0,69.9 L 48.5,71.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-15 atom-17' d='M 53.3,70.6 L 48.8,72.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 61.5,62.5 L 63.5,56.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 63.5,56.3 L 59.1,51.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 59.1,51.4 L 61.0,45.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 59.1,51.4 L 52.7,52.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-20 atom-22' d='M 58.4,52.9 L 53.9,53.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-23 atom-24' d='M 31.6,32.8 L 25.2,34.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-23 atom-24' d='M 30.3,31.8 L 25.8,32.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-46 atom-45 atom-23' d='M 33.3,26.5 L 31.6,32.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-24 atom-25' d='M 25.2,34.5 L 23.5,40.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-26' d='M 25.2,34.5 L 20.6,29.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-26 atom-27' d='M 20.6,29.8 L 22.3,23.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-27 atom-28' d='M 22.3,23.5 L 28.7,21.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-28 atom-29' d='M 28.7,21.8 L 30.4,15.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-47 atom-45 atom-28' d='M 33.3,26.5 L 28.7,21.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-49 atom-28 atom-46' d='M 27.8,20.8 L 27.5,21.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-49 atom-28 atom-46' d='M 26.8,19.8 L 26.3,20.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-49 atom-28 atom-46' d='M 25.9,18.8 L 25.1,19.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-29 atom-30' d='M 30.4,15.5 L 29.9,8.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-29 atom-29 atom-31' d='M 30.4,15.5 L 24.0,14.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-29 atom-32' d='M 30.4,15.5 L 32.6,14.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-29 atom-32' d='M 32.6,14.9 L 34.8,14.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-32 atom-33' d='M 38.7,15.8 L 40.1,17.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-32 atom-33' d='M 40.1,17.1 L 41.4,18.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-33 atom-34' d='M 41.4,18.5 L 47.7,16.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-33 atom-34' d='M 42.7,19.5 L 47.1,18.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-48 atom-44 atom-33' d='M 39.7,24.8 L 41.4,18.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-33 atom-34 atom-35' d='M 47.7,16.8 L 52.4,21.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-34 atom-35 atom-36' d='M 52.4,21.5 L 58.7,19.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-39 atom-35 atom-41' d='M 52.4,21.5 L 50.6,27.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-39 atom-35 atom-41' d='M 50.8,22.1 L 49.6,26.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-35 atom-36 atom-37' d='M 58.7,19.8 L 63.3,24.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-36 atom-37 atom-38' d='M 63.3,24.5 L 69.7,22.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-37 atom-38 atom-39' d='M 69.7,22.9 L 74.3,27.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-38 atom-39 atom-40' d='M 74.3,27.5 L 80.6,25.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-40 atom-41 atom-42' d='M 50.6,27.8 L 44.3,29.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-41 atom-42 atom-43' d='M 44.3,29.5 L 43.7,31.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-41 atom-42 atom-43' d='M 43.7,31.7 L 43.1,33.9' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-42 atom-42 atom-44' d='M 44.3,29.5 L 39.7,24.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-42 atom-42 atom-44' d='M 44.5,27.9 L 41.3,24.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-43 atom-44 atom-45' d='M 39.7,24.8 L 33.3,26.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-50 atom-45 atom-47' d='M 33.3,26.5 L 35.5,29.6 L 36.4,28.7 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<text x='43.3' y='73.7' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='47.4' y='73.7' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='40.0' y='52.5' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='44.1' y='52.5' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='35.0' y='16.8' class='atom-32' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='40.7' y='38.8' class='atom-43' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='44.9' y='38.8' class='atom-43' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='21.7' y='20.7' class='atom-46' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='36.1' y='34.2' class='atom-47' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 OC1=CC(CCCCC)=CC(O)=C1C1[[email protected]](C(C)=C)CCC(C)=C1.C1=C(C)CC[[email protected]]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[[email protected]@H]21 SSNHGLKFJISNTR-FWUPRJFYSA-N 0.000 description 2
  • 235000008697 Cannabis sativa Nutrition 0.000 description 2
  • 206010061428 Decreased appetite Diseases 0.000 description 2
  • 235000012631 food intake Nutrition 0.000 description 2
  • 150000002823 nitrates Chemical class 0.000 description 2
  • 239000011347 resin Substances 0.000 description 2
  • 229920005989 resin Polymers 0.000 description 2
  • 238000005507 spraying Methods 0.000 description 2
  • 108010043024 Botulinum Toxins Proteins 0.000 description 1
  • 229940030609 CALCIUM CHANNEL BLOCKERS Drugs 0.000 description 1
  • 241000638023 Cannabis sativa subsp. indica Species 0.000 description 1
  • 206010012335 Dependence Diseases 0.000 description 1
  • 206010017885 Gastrooesophageal reflux disease Diseases 0.000 description 1
  • 108010037799 HLA-DQ1 antigen Proteins 0.000 description 1
  • 210000003128 Head Anatomy 0.000 description 1
  • 102000003814 Interleukin-10 Human genes 0.000 description 1
  • 108090000174 Interleukin-10 Proteins 0.000 description 1
  • 229940076144 Interleukin-10 Drugs 0.000 description 1
  • 231100000601 Intoxication Toxicity 0.000 description 1
  • 208000008085 Migraine Disorders Diseases 0.000 description 1
  • 210000004400 Mucous Membrane Anatomy 0.000 description 1
  • 208000008238 Muscle Spasticity Diseases 0.000 description 1
  • 229940041678 Oral Spray Drugs 0.000 description 1
  • 208000005374 Poisoning Diseases 0.000 description 1
  • 210000003296 Saliva Anatomy 0.000 description 1
  • 238000010521 absorption reaction Methods 0.000 description 1
  • 239000004480 active ingredient Substances 0.000 description 1
  • 238000004458 analytical method Methods 0.000 description 1
  • 230000037396 body weight Effects 0.000 description 1
  • 229940053031 botulinum toxin Drugs 0.000 description 1
  • 239000000480 calcium channel blocker Substances 0.000 description 1
  • 244000213578 camo Species 0.000 description 1
  • 235000009120 camo Nutrition 0.000 description 1
  • 229930003827 cannabinoid Natural products 0.000 description 1
  • 239000003557 cannabinoid Substances 0.000 description 1
  • 230000002149 cannabinoid Effects 0.000 description 1
  • 229940065144 cannabinoids Drugs 0.000 description 1
  • 239000000969 carrier Substances 0.000 description 1
  • 210000000038 chest Anatomy 0.000 description 1
  • 239000000470 constituent Substances 0.000 description 1
  • LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
  • 238000001704 evaporation Methods 0.000 description 1
  • 239000000284 extract Substances 0.000 description 1
  • 238000000605 extraction Methods 0.000 description 1
  • 238000009472 formulation Methods 0.000 description 1
  • 230000002068 genetic Effects 0.000 description 1
  • 230000002650 habitual Effects 0.000 description 1
  • 238000002347 injection Methods 0.000 description 1
  • 239000007924 injection Substances 0.000 description 1
  • 230000000968 intestinal Effects 0.000 description 1
  • 230000035987 intoxication Effects 0.000 description 1
  • 231100000566 intoxication Toxicity 0.000 description 1
  • 238000002955 isolation Methods 0.000 description 1
  • 239000007788 liquid Substances 0.000 description 1
  • 238000002156 mixing Methods 0.000 description 1
  • 230000004899 motility Effects 0.000 description 1
  • 201000006417 multiple sclerosis Diseases 0.000 description 1
  • 239000000668 oral spray Substances 0.000 description 1
  • 102000014187 peptide receptors Human genes 0.000 description 1
  • 108010011903 peptide receptors Proteins 0.000 description 1
  • 230000000506 psychotropic Effects 0.000 description 1
  • 230000000306 recurrent Effects 0.000 description 1
  • 231100000486 side effect Toxicity 0.000 description 1
  • 239000000779 smoke Substances 0.000 description 1
  • 239000007787 solid Substances 0.000 description 1
  • 239000000243 solution Substances 0.000 description 1
  • 239000000725 suspension Substances 0.000 description 1
  • 238000003786 synthesis reaction Methods 0.000 description 1
  • 230000002227 vasoactive Effects 0.000 description 1
  • 235000019786 weight gain Nutrition 0.000 description 1
  • 230000004584 weight gain Effects 0.000 description 1
See also  Which is better for pain cbd oil or cream

Classifications

    • A — HUMAN NECESSITIES
    • A61 — MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K — PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00 — Medicinal preparations containing organic active ingredients
    • A61K31/33 — Heterocyclic compounds
    • A61K31/335 — Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35 — Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352 — Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
    • A — HUMAN NECESSITIES
    • A61 — MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P — SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00 — Drugs for disorders of the alimentary tract or the digestive system
    • A — HUMAN NECESSITIES
    • A61 — MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P — SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00 — Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06 — Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia

    Abstract

    The present invention relates to the use of an association of Δ9-tetrahydrocannabinolic acid (THC) and cannabidiol (CBD) for the treatment of achalasia or at least one of the symptoms thereof.

    Description

    Utilisation de cannabis pour le traitement de l’achalasie Use of cannabis for the treatment of achalasia

    La présente invention se rapporte au traitement thérapeutique de l’achalasie ; elle a plus particulièrement pour objet une nouvelle utilisation thérapeutique du cannabis pour le traitement de l’achalasie et de ses symptômes. The present invention relates to the therapeutic treatment of achalasia; it more particularly relates to a new therapeutic use of cannabis for the treatment of achalasia and its symptoms.

    L’achalasie est un trouble de la motilité de l’œsophage accompagné d’un défaut de relâchement du sphincter inférieur de l’œsophage ; elle se traduit par une dysphagie, la régurgitation d’aliments non digérés, une anorexie et une perte de poids (Boeckxstaens et ai. (2014) Lancet 383 (991 l):83-90). Achalasia is a disorder of the motility of the esophagus accompanied by a lack of relaxation of the lower esophageal sphincter; it results in dysphagia, regurgitation of undigested foods, anorexia and weight loss (Boeckxstaens et al. (2014) Lancet 383 (991 l): 83-90).

    Le taux d’incidence est de 0,5 à 1 cas pour 100 000 habitants par an, à peu près comparable selon les pays. La prévalence est de 1 pour 10000. L’âge de survenue s’étend d’environ 25 à 60 ans, îa maladie peut survenir chez des sujets plus jeunes avec une moindre fréquence, l’incidence augmentant avec l’âge. Cette affection touche aussi bien les hommes que les femmes. The incidence rate is 0.5 to 1 per 100,000 inhabitants per year, roughly comparable across countries. The prevalence is 1 in 10,000. The age of onset ranges from about 25 to 60 years, the disease may occur in younger subjects with a lower frequency, the incidence increasing with age. This condition affects men as well as women.

    11 existe des prédispositions génétiques, en particulier chez les porteurs de l’HLA-DQl , de certains ailèles du VIPRÎ (récepteur 1 du peptide vasoactif intestinal), du promoteur de l’interleukine 10. There are genetic predispositions, particularly in carriers of HLA-DQ1, of certain VIPR1 (intestinal vasoactive peptide receptor 1), and interleukin 10 promoter.

    Les traitements de l’achalasie comprennent des thérapies qui s’appuient actuellement sur deux classes de molécules prescrites : les inhibiteurs calciques et les dérivés nitrés ; cependant aucune molécule appartenant à ces deux classes de produit n’a été reconnue comme efficace (Wen et al. (2004) Cochrane Database Syst Rev(l ) CD002299 ; Boeckxstaens et al, 2014). The treatments for achalasia include therapies currently based on two classes of prescribed molecules: calcium channel blockers and nitrates; however, no molecule belonging to these two classes of product has been recognized as effective (Wen et al., (2004) Cochrane Database Syst Rev (1) CD002299, Boeckxstaens et al, 2014).

    Alternativement à ces thérapies, il existe des méthodes de traitement invasives (Boeckxstaens et al , 2014 ; Leyden et al. (2006) Cochrane Database Syst Rev (4) CD00 046) qui comprennent ; As an alternative to these therapies, there are invasive methods of treatment (Boeckxstaens et al, 2014, Leyden et al., (2006) Cochrane Database Syst Rev (4) CD00 046) which include;

    ~ l’injection de toxine botulique par voie endoscopique au niveau du sphincter du bas de l’œsophage ; ~ injection of botulinum toxin endoscopically at the level of the lower esophageal sphincter;

    – îa dilatation pneumatique ; elle consiste en l’introduction d’un ballon au niveau de la jonction œsogastrique et qui est ensuite gonflé sous une pression déterminée jusqu’à entraîner une déchirure du sphincter du bas œsophage ; cette procédure peut être éventuellement répétée en employant dans un second temps, un ballon de diamètre plus grand ; pneumatic expansion; it consists of the introduction of a balloon at the oesogastric junction and which is then inflated under a determined pressure to cause tearing of the sphincter of the lower esophagus; this procedure can possibly be repeated by using in a second time, a larger diameter balloon;

    – la cardiomyotomie laparoscopique qui consiste à sectionner le sphincter du bas œsophage ; cette technique semble être très efficace sur les symptômes (réponse supérieure à 90%) mais elle pose un risque de reflux gastro-œsophagien qui pourrait atteindre un patient sur deux ; et Laparoscopic cardiomyotomy which consists of sectioning the lower esophageal sphincter; this technique seems to be very effective on the symptoms (response greater than 90%) but it poses a risk of gastro-oesophageal reflux which could reach one out of two patients; and

    – l’ sophagectomie (ablation partielle ou totale de l’œsophage). – the sophagectomy (partial or total removal of the esophagus).

    Malheureusement, l’ensemble de ces techniques est caractérisé par un taux de rechute important et des symptômes récidivants nécessitant le renouvellement des interventions. Unfortunately, all of these techniques are characterized by a high rate of relapse and recurrent symptoms requiring the renewal of interventions.

    L’achalasie est un trouble marqué par une franche altération de la qualité de vie et un degré important d’incapacité. Il demeure donc nécessaire de mettre au point un traitement efficace de tout ou partie des symptômes de l’achalasie et qui soit le moins invasif possible. Achalasia is a disorder marked by a sharp deterioration in the quality of life and a significant degree of disability. It remains necessary to develop an effective treatment of all or part of the symptoms of achalasia and that is the least invasive possible.

    Dans le cadre du traitement de ses patients, la Demanderesse a observé un effet bénéfique du cannabis sur le traitement des symptômes de l’achalasie. In the context of the treatment of its patients, the Applicant has observed a beneficial effect of cannabis on the treatment of the symptoms of achalasia.

    Cet effet se traduit par une amélioration de l’ensemble des symptômes de l’achalasie incluant, en particulier, une amélioration de l’ingestion des aliments et une prise de poids. This effect results in an improvement of all the symptoms of achalasia including, in particular, an improvement in the ingestion of food and weight gain.

    L’effet thérapeutique du cannabis provient de l’association de deux cannabinoïdes, l’acide A9-tetrahydrocannabinolique (THC) qui possède un caractère psychotrope The therapeutic effect of cannabis comes from the combination of two cannabinoids, A9-tetrahydrocannabinolic acid (THC) which has a psychotropic character

    qui est un constituant majeur de la plante, représentant jusqu’à 40% de ses extraits. C’est un composant non-psychoactif de la plante qui, contrairement au THC, ne provoque pas l’ivresse habituelle du cannabis ; le cannabidiol est capable de contrebalancer la dépendance au THC lorsque le ratio THC : CBD est de l’ordre de 1 (Syed et al. (2014) Drugs 74(5) :563-78). Ainsi, la présente invention se rapporte à l’utilisation de l’association d’acide A9-tetrahydrocannabinolique (THC) et de cannabidiol (CBD) pour le traitement de l’achalasie et de ses symptômes. which is a major constituent of the plant, representing up to 40% of its extracts. It is a non-psychoactive component of the plant that, unlike THC, does not cause the habitual intoxication of cannabis; cannabidiol is able to counterbalance THC dependence when the THC: CBD ratio is in the range of 1 (Syed et al (2014) Drugs 74 (5): 563-78). Thus, the present invention relates to the use of the combination of A9-tetrahydrocannabinolic acid (THC) and cannabidiol (CBD) for the treatment of achalasia and its symptoms.

    Cette association de THC et de CBD peut provenir du cannabis (Cannabis Sativa, notamment Cannabis sativa indica, Cannabis sativa saliva, et Cannabis ruderalis ou leur croisement) ; dans ce cas, tout produit extrait de la plante peut être utilisé. This combination of THC and CBD can come from cannabis (Cannabis Sativa, especially Cannabis sativa indica, Cannabis sativa saliva, and Cannabis ruderalis or their cross); in this case, any product extracted from the plant can be used.

    A titre d’exemple, il peut s’agir d’herbe qui correspond aux feuilles et aux sommités fleuries séchées (mélange de graines et de brindilles) ; de résine qui se présente sous forme de barrettes ayant un aspect brun à noir et plus ou moins solide ; l’huile qui est un liquide visqueux brun-vert résultant de l’extraction de la résine par de l’alcool à 90°C suivie d’une évaporation (« 2006 – World Drug Report – volume 1 : analysis » de United Nations – Office on Drugs and Crime, voir en particulier l’Annexe 1). For example, it may be grass that corresponds to the leaves and flower heads dried (mixture of seeds and twigs); resin which is in the form of bars having a brown to black and more or less solid appearance; the oil which is a viscous brown-green liquid resulting from the extraction of the resin by alcohol at 90 ° C followed by evaporation (“2006 – World Drug Report – volume 1: analysis” of United Nations – Office on Drugs and Crime, see in particular Appendix 1).

    Alternativement, association est préparée par mélange de chacun de ces deux actifs soit après isolement à partir de la plante, soit après synthèse chimique Alternatively, combination is prepared by mixing each of these two active ingredients either after isolation from the plant or after chemical synthesis

    Les voies d’administration peuvent inclure l’inhalation de la fumée, l’ingestion, le vapotage, la pulvérisation ou la vaporisation sur les muqueuses. , . Routes of administration may include inhalation of smoke, ingestion, vaping, spraying or spraying on the mucous membranes. ,.

    L’homme du métier saura adapter la formulation de l’association selon le mode d’administration retenu. Those skilled in the art will be able to adapt the formulation of the association according to the method of administration chosen.

    L’effet thérapeutique de l’association est observé quel que soit le ratio The therapeutic effect of the combination is observed regardless of the ratio

    CBD : THC ; toutefois, pour éviter l’apparition d’une dépendance à la thérapie, il est préférable que ce ratio pondéral CBD : THC soit d’au moins 0,75 : I , c’est à dire que la teneur de CBD soit d’au moins 0,75 unité de poids pour une teneur en THC de 1 de la même unité de poids ; préférentiellement, ce ratio CBD : THC est compris entre 0,75 : 1 et 50 : 1. CBD: THC; however, to avoid the onset of therapy dependence, it is preferable that this CBD: THC weight ratio be at least 0.75: I, ie the CBD content is at least minus 0.75 weight units for a THC content of 1 of the same unit weight; preferably, this CBD: THC ratio is between 0.75: 1 and 50: 1.

    De préférence, la posologie de l’association est telle qu’elle représente un apport quotidien en THC compris entre 1 et 100 mg et un apport quotidien en CBD compris entre 1 et î 00 mg. Preferably, the dosage of the combination is such that it represents a daily intake of THC between 1 and 100 mg and a daily intake of CBD of between 1 and 100 mg.

    Selon une variante préférée, le traitement est mis en œuvre à l’aide de cannabis médical, tel que le produit Sativex développé pour une autre utilisation thérapeutique : le traitement des symptômes liés à une spasticité due à la sclérose en plaque. Ce produit est sous la forme d’une solution pour pulvérisation buccale comprenant 27 mg de THC et 25 mg de CBD par ml de suspension ; l’avantage de ce produit est qu’il n’a pas été retrouvé en clinique de cas de patients développant une addiction au Sativex. According to a preferred variant, the treatment is carried out using medical cannabis, such as the product Sativex developed for another therapeutic use: the treatment of symptoms related to spasticity due to multiple sclerosis. plate. This product is in the form of an oral spray solution comprising 27 mg of THC and 25 mg of CBD per ml of suspension; the advantage of this product is that it has not been found in clinical cases of patients developing a Sativex addiction.

    L’utilisation de l’association de THC et de CBD conduit au traitement des différents troubles associés à l’achaiasie incluant l’hypertonicité du sphincter inférieur de l’œsophage ; la dysphagie, c’est-à-dire la diminution de la sensation de gêne ou de blocage ressentie au moment de l’alimentation, lors du passage des aliments dans la bouche, le pharynx ou l’œsophage ; des douleurs thoraciques ; les régurgitations ; le dégoût des aliments et la perte de poids. The use of the combination of THC and CBD leads to the treatment of various disorders associated with achaiasia including hypertonicity of the lower esophageal sphincter; dysphagia, that is to say, the decrease of the feeling of discomfort or blockage felt at the time of feeding, during the passage of food in the mouth, pharynx or esophagus; chest pain; regurgitations; disgusting food and losing weight.

    Plus particulièrement, l’utilisation de l’association de THC et de CBD permet : More particularly, the use of the combination of THC and CBD makes it possible:

    – la relaxation du sphincter bas (ou inférieur) de l’œsophage ; – relaxation of the lower (or lower) sphincter of the esophagus;

    – la réduction de la dysphagie et donc à la diminution de la sensation de gêne ou de blocage ressentie au moment de l’alimentation, lors du passage des aliments dans la bouche, le pharynx ou l’œsophage ; – the reduction of dysphagia and therefore the decrease of the feeling of discomfort or blockage felt at the time of feeding, during the passage of food in the mouth, pharynx or esophagus;

    – la diminution ou la disparition des régurgitations ; – the decrease or disappearance of regurgitations;

    – la diminution ou la disparition des douleurs thoraciques (au niveau de la poitrine) ; – decrease or disappearance of chest pain (in the chest);

    La présente invention se rapporte également à une composition pharmaceutique comprenant une association d’acide A9-tetrahydrocannabinolique (THC) et de cannabidiol (CBD) telle que décrite précédemment dans un véhicule pharmaceutiquement acceptable pour le traitement de l’achaiasie ou d’au moins un de ses symptômes précités. The present invention also relates to a pharmaceutical composition comprising a combination of A9-tetrahydrocannabinolic acid (THC) and cannabidiol (CBD) as previously described in a pharmaceutically acceptable vehicle for the treatment of achaiasia or at least one of his aforementioned symptoms.

    La présente invention se rapporte encore à une méthode de traitement d’au moins un des symptômes de l’achaiasie par administration de l’association d’acide A9-tetrahydrocannabinolique (THC) et de cannabidiol (CBD) ou d’une composition pharmaceutique la comprenant. The present invention further relates to a method of treating at least one of the symptoms of achaiasis by administering the combination of A9-tetrahydrocannabinolic acid (THC) and cannabidiol (CBD) or a pharmaceutical composition of the present invention. comprising.

    L’effet bénéfique de l’association de THC et de CBD a été observé chez un patient chez qui l’achaiasie a été diagnostiquée à l’âge de 15 ans et provoquait une invalidité importante résultant de symptômes très prononcés : régurgitation de nourriture non digérée, dysphagie, anorexie et perte de poids. The beneficial effect of the combination of THC and CBD was observed in a patient in whom achaiasia was diagnosed at age 15 and caused a significant disability resulting from very pronounced symptoms: regurgitation of undigested food, dysphagia, anorexia and weight loss.

    Aucune des thérapies connues de l’achalasie n’a permis d’améliorer significativement et à long terme sa pathologie : la prescription de nitrates a conduit à des effets secondaires indésirables (migraines) ; une dilatation pneumatique réalisée à None of the known therapies of achalasia has significantly improved its long-term pathology: the prescription of nitrates has led to undesirable side effects (migraines); a pneumatic dilation performed at

    17 ans a permis une diminution des symptômes de l’achalasie pendant deux mois avant que le sujet présente une rechute très sévère conduisant à une perte de poids marquée de 27% du poids corporel et un dégo t prononcé de la nourriture ; ce patient a ensuite subi une cardiomyotomie laparoscopique dont les bénéfices n’ont perduré que 3 mois avant, là encore, de provoquer une rechute des symptômes de l’achalasie. 17 years of age reduced the symptoms of achalasia for two months before the subject experienced a very severe relapse leading to a marked weight loss of 27% of body weight and a pronounced loss of food; this patient then underwent laparoscopic cardiomyotomy whose benefits lasted only 3 months before, again, causing a relapse of the symptoms of achalasia.

    Ce n’est qu’avec une consommation quotidienne de cannabis que ce patient a immédiatement ressenti une amélioration des symptômes de la maladie en particulier en facilitant la prise alimentaire ; l’inhalation d’un joint contenant 0,5 g de cannabis présente un taux de THC total de 10% conduit à l’absorption d’une dose d’environ 7,5 à 54 mg de THC (source “World Drug Report 2006, WHO Report // 1UML-CG 200740-22 ” http://www.lnt.ch7Cannabisficheinfo.pdf) et d’environ 0,3 à It was only with daily cannabis consumption that this patient immediately felt an improvement in the symptoms of the disease, in particular by facilitating food intake; inhalation of a joint containing 0.5 g of cannabis has a total THC content of 10% leads to the absorption of a dose of approximately 7.5 to 54 mg of THC (source “World Drug Report 2006 , WHO Report // 1UML-CG 200740-22 “http: //www.lnt.ch7Cannabisficheinfo.pdf) and about 0.3 to

    2 mg de CBD. Cette administration quotidienne a permis une amélioration de l’ensemble du tableau clinique de la maladie. 2 mg of CBD. This daily administration has improved the overall clinical picture of the disease.

    L’amélioration des symptômes de l’achalasie résultant de la consommation quotidienne de cannabis a été observée sur plusieurs années au cours desquelles le patient a été suivi médicalement mais avec une intensité moins importante et n’a plus eu besoin de traitement médicamenteux. The improvement in the symptoms of achalasia resulting from daily cannabis use was observed over several years during which the patient was followed medically but with less intensity and no longer needed medication.

    Claims

    1. Association d’acide A9-tetrahydrocannabmolique (THC) et de cannabidiol (CBD) pour le traitement de l’achalasie ou d’au moins un des symptômes de l’achalasie. 1. Association of A9-tetrahydrocannabmolic acid (THC) and cannabidiol (CBD) for the treatment of achalasia or at least one of the symptoms of achalasia.

    2. Association de THC et de CBD pour son utilisation selon la revendication 1 , caractérisée en ce que ie ratio pondéral THC : CBD est d’au moins 0,75 : 1 . 2. Association of THC and CBD for use according to claim 1, characterized in that the THC: CBD weight ratio is at least 0.75: 1.

    3. Association de THC et de CBD pour son utilisation selon la revendication î ou la revendication 2, caractérisée en ce qu’elle représente un apport quotidien en THC compris entre 1 et 100 mg et un apport quotidien en CBD compris entre 1 et 100 mg. 3. Association of THC and CBD for its use according to claim 1 or claim 2, characterized in that it represents a daily intake of THC between 1 and 100 mg and a daily intake of CBD between 1 and 100 mg .

    4. Association de THC et de CBD pour son utilisation selon l’une quelconque des revendications qui précèdent, pour le traitement d’au moins un trouble associé à l’achalasie choisi parmi l’hypertonicité du sphincter bas de l’œsophage ; la dysphagie ; les douleurs thoraciques ; les régurgitations ; le dégoût des aliments et la perte de poids. 4. Association of THC and CBD for use according to any one of the preceding claims for the treatment of at least one achalasia-associated disorder selected from low esophageal sphincter hypertonicity; dysphagia; chest pain; regurgitations; disgusting food and losing weight.

    5. Association de THC et de CBD pour son utilisation selon l’une quelconque des revendications qui précèdent, pour augmenter la relaxation du sphincter bas de l’œsophage ; pour la réduction de la dysphagie et la diminution de la sensation de gêne ou de blocage ressentie au moment de l’alimentation, lors du passage des aliments dans la bouche, le pharynx ou l’œsophage ; pour la diminution ou la disparition des régurgitations ; et pour la diminution ou la disparition des douleurs thoraciques ; pour améliorer la prise des aliments et/ou pour éviter la perte de poids ou en favoriser la prise. 5. Association of THC and CBD for use according to any one of the preceding claims to increase relaxation of the lower esophageal sphincter; for the reduction of dysphagia and the decrease of the feeling of discomfort or blockage felt at the time of feeding, during the passage of food in the mouth, pharynx or esophagus; for the diminution or the disappearance of the regurgitations; and for the reduction or disappearance of chest pain; to improve the intake of food and / or to prevent weight loss or to promote its intake.

    6. Composition pharmaceutique comprenant une association d’acide A9-tetrahydrocannabinoîique (THC) et de cannabidiol (CBD) dans un véhicule pharmaceutiquement acceptable pour le traitement de l’achalasie ou d’au moins un de ses symptômes. A pharmaceutical composition comprising a combination of 9-tetrahydrocannabinoic acid (THC) and cannabidiol (CBD) in a pharmaceutically acceptable carrier for the treatment of achalasia or at least one of its symptoms.

    7. Composition pharmaceutique pour son utilisation selon la revendication 6, pour le traitement d’au moins un trouble associé à l’achalasie choisi parmi l’hypertonicité du sphincter bas de l’œsophage ; la dysphagie ; les douleurs thoraciques ; les régurgitations ; le dégoût des aliments et la perte de poids. A pharmaceutical composition for use according to claim 6 for the treatment of at least one achalasia-associated disorder selected from low esophageal sphincter hypertonicity; dysphagia; chest pain; regurgitations; disgusting food and losing weight.

    8. Composition pharmaceutique pour son utilisation selon la revendication 6 ou la revendication 7,pour augmenter la relaxation du sphincter bas de l’œsophage ; pour la réduction de ia dysphagie et la diminution de la sensation de gêne ou de blocage ressentie au moment de l’alimentation, lors du passage des aiiments dans la bouche, le pharynx ou l’œsophage ; pour la diminution ou la disparition des régurgitations ; et pour la diminution ou la disparition des douleurs thoraciques ; pour améliorer la prise des aliments et/ou pour éviter la perte de poids ou en favoriser la prise. A pharmaceutical composition for use as claimed in claim 6 or claim 7 for increasing relaxation of the lower esophageal sphincter; for the reduction of dysphagia and the decrease of the sensation of discomfort or blockage felt at the time of feeding, during the passage of nutrients in the mouth, pharynx or esophagus; for the diminution or the disappearance of the regurgitations; and for the reduction or disappearance of chest pain; to improve the intake of food and / or to prevent weight loss or to promote its intake.

    PCT/IB2015/054684 2014-06-23 2015-06-23 Use of cannabis for the treatment of achalasia WO2015198209A1 ( en )

    See also  Best hemp cbd oil for chronic pain and fibromyalgia