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Cbd oil 1000mg for anxiety

What Dosage of CBD Should You Take?

Kendra Cherry, MS, is an author and educational consultant focused on helping students learn about psychology.

Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more.

John C. Umhau, MD, MPH, CPE is board-certified in addiction medicine and preventative medicine. He is the medical director at Alcohol Recovery Medicine. For over 20 years Dr. Umhau was a senior clinical investigator at the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health (NIH).

Verywell / Madelyn Goodnight

CBD is available in a number of different formulations including creams, tablets, oils, and gummies. These can vary in terms of their ingredients as well as dosages, and there is not a great deal of research available on what dose might be beneficial or safe to treat certain conditions.

Cannabidiol (CBD) is the second most abundant cannabinoid found in marijuana. Unlike tetrahydrocannabinol (THC), CBD does not have psychoactive effects. Interest in the use of CBD for health purposes has grown tremendously in the last few years.

CBD is believed to have a range of positive physical and mental health effects. Because of this, it has become increasingly popular as a way to alleviate everything from anxiety to sleep disorders.

In order to determine if CBD is right for you, it is important to consider its potential benefits, side effects, and available research on safe dosages.

Possible Benefits

CBD is just one of hundreds of different compounds found in the cannabis plant. While cannabis has been used in holistic medicine for many years, only recently have researchers begun to explore some of the medicinal purposes for CBD and other cannabinoids.

While further research is still needed, there is some evidence that CBD may have some beneficial mental health effects. These include:

  • Alleviating depression: Some research also indicates that CBD may be useful as a treatment for depression. Studies suggest that the cannabinoid might have an influence on how the brain responds to serotonin, a neurotransmitter that plays a key role in mood. People with depression sometimes have a low level of serotonin, so CBD may help the brain use available serotonin more effectively.
  • Improving sleep: While the reasons are not entirely understood and require further research, CBD also appears to have potential as a treatment for sleep problems. For example, one study found that people who took CBD also reported improvements in the quality of their sleep.
  • Reducing anxiety: Anxiety is one of the most common types of mental health conditions, affecting almost 20% of American adults each year. Research suggests that CBD may help alleviate acute symptoms of a number of anxiety-related conditions including generalized anxiety disorder, obsessive-compulsive disorder, and social anxiety disorder.

In addition to the mental health benefits, CBD may also have therapeutic benefits for a range of other conditions. The World Health Organization suggests that CBD may have beneficial effects in the treatment of:

  • Alzheimer’s disease
  • Arthritis
  • Cardiovascular disease
  • Diabetes
  • Infection
  • Inflammation
  • Multiple sclerosis
  • Nausea
  • Pain
  • Psychosis

It is important to remember that these benefits have not yet been conclusively proven. More research is needed to determine the role that CBD might play in the treatment of different disorders and health conditions.

Research

There have been a number of studies that suggest that CBD may have a number of different physical and mental health uses. However, more research is still needed to better understand the substance’s potential applications and possible long-term side effects.

A 2019 comprehensive review published in The Lancet Psychiatry looked at previously published studies. The review ultimately concluded that there was little evidence to support the use of CBD for mental health purposes and suggested that more research is needed in order to substantiate its use to treat symptoms of conditions such as anxiety, depression, and insomnia.

It is important to remember that this doesn’t mean that CBD isn’t effective. Many of the studies that were included in the review were small, had few participants, and were not randomized controlled trials.

This suggests that more research involving more participants and well-designed studies is needed in order to better understand if, how, and why CBD works.

While its effectiveness is still up for debate, one 2017 review found that it was a relatively safe option.   While it is important to remember that there is still a great deal we don’t yet know about CBD and its effects, it is something that you might opt to try to see if you experience any benefits.

How Much Should You Take?

The dosages used in research studies vary and there is no consensus on how much should be used for specific conditions. If you do decide to try CBD, it is also important to note that there is no universally agreed upon dose. Research also suggests that people may respond differently to various dosages, so the amount that is right for your needs might vary.

CBD Dosages

Some dosages that have been used in research studies for different conditions include:

  • Anxiety: 300 to 600 mg
  • Bowel disease: 10 mg per day
  • Cancer-related pain: 50 to 600 mg per day
  • Parkinson’s disease: 75 to 300 mg per day
  • Poor sleep: 25 mg per day
  • Psychosis: 600 mg per day
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One 2020 review of studies found that participants showed improvements in anxiety levels after single doses of CBD ranging from 300 to 600 mg.   Such results indicate that the CBD may hold promise as a treatment to alleviate symptoms of acute anxiety.

It is important to remember that you should always talk to your doctor before using CBD if you have symptoms of a serious mental or physical health condition. CBD could potentially worsen symptoms or interact with other medications you are taking.

Looking at the dosage information for the CBD product that has been FDA approved can also be helpful. For Epidiolex, an FDA-approved cannabis-derived medication used to treat seizures in people with certain types of epilepsy, the starting dosage is 5 milligrams per kilogram of body weight. This dose can later be increased to 5 mg per kilogram of body weight twice a day.

Other CBD products are not FDA regulated and do not have officially recommended dosages. This can make it difficult to determine how much you might need, but there are some things you can consider that might help.

  • Assess your sensitivity to CBD: Your individual ability to tolerate CBD can also play a role in determining how much you need. If you are very sensitive to the effects of CBD, you should take a small dose. Some people may find that they are not as affected by the substance, so they may need to take a larger dose to notice any beneficial effects.
  • Consider individual factors: When you are trying to decide how much CBD to take, there are a number of factors you should consider. These include the formulation and concentration of the capsule, oil drops, or gummies you are taking, the symptoms you are treating, and your age, sex, weight, and overall health. Generally, people with heavier bodies need to take a little more to achieve the same effects. Men may need a larger dose, while older people may need less.
  • Consider the symptoms you’re treating: The symptoms you are trying to alleviate can also play a role in the CBD dosage you need to take to see results. In one study, participants who took 25mg of CBD each day had improved sleep quality, although the results were not consistent.   However, you might find that you need a lower or higher dose if you are treating another type of condition.
  • Try a dosage calculator: Researchers note that while the variety of dosing strategies and formulations make it difficult to determine efficacy, there are a number of online “dose-calculators” available online (such as mydosage.com) that are designed to help people choose the correct dose.   The accuracy of such calculators is difficult to assess, but it may be a good place to start.

Before you try CBD, discuss your plan with your doctor. They may be able to recommend a dose and help you better understand any potential risks, complications, side effects, or interactions you might experience.

Start With a Low Dose

Unless your doctor recommends a specific dose, start by taking 10 to 20 mg a day. Take this for a week to ensure that it is well-tolerated and that you don’t experience any unwanted effects or an allergic reaction.

If this dose does not have the desired effect, try increasing in increments of 5mg each week until the desired amount is reached.

In studies, amounts vary from as low as 20 milligrams per day to up to 1,500 milligrams (mg) per day. The World Health Organization reports that dosages in clinical research studies typically range between 100 and 800 milligrams per day.  

Is It Possible to Take Too Much?

So what is the maximum amount of CBD you should take? Researchers have found that 600 mg per day appears to be safe, but one study suggested that doses of up to 1,500 mg a day are safe and tolerated well.

However, it’s important to remember that research is still in its infancy and experts do not yet fully understand the potential long-term impacts of CBD usage. For that reason, you should always discuss your CBD use with your doctor.

Starting at a lower dose and working your way up to the amount you need may be the best ways to avoid taking too much.

How to Take CBD

The amount of CBD found in a product may depend on different factors, including the formulation and method of administration. CBD products are available in a number of different forms including oils, capsules, tablets, nasal sprays, and gummies.

One of the most popular ways to take CBD is as an oil. Such products are made by combining CBD with some type of carrier oil, such as coconut oil. Some more recently developed products include dietary supplements, foods, beverages, lotions, salves, and cosmetics.

The type of CBD product you choose may depend on what you are trying to treat. If you are looking for general mood improvements, a dietary supplement might be a good option.

If you are targeting specific symptoms of a condition, taking an oil, capsule, or gummy might be a better way to obtain a higher, more concentrated dose.

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Topical applications may produce localized effects, but they are unlike to have any mental health benefits.

What Kind Should You Take?

It’s also important to remember that many products don’t contain just CBD on its own. There are three types of CBD available:

  • Isolate contains CBD and only CBD.
  • Broad-spectrum contains CBD and other cannabinoids, but not THC.
  • Full-spectrum contains CBD, THC, and other cannabinoids.

It may be helpful to take a broad-spectrum product since research suggests that CBD’s effects may be most beneficial when taken in conjunction with other cannabinoids, a phenomenon known as the entourage effect. CBD may also help mitigate some of the effects of THC.

Side Effects

While CBD is generally well-tolerated, this does not mean that you won’t experience any side effects.

Some of the most common side effects that people experience when taking CBD include:

  • Appetite changes
  • Diarrhea
  • Nausea
  • Dizziness
  • Stomach upset
  • Weight changes

Some recent research has generated concerns over the safety and potential long term effects of CBD. One study involved giving mice an equivalent of the maximum dose of the CBD medication Epidiolex, which is used to treat certain forms of epilepsy. The results indicated an increased risk for liver damage as well as concerns over its interaction with other medications.  

Safety

It is also important to remember that CBD products are not regulated by the U.S. Food and Drug Administration (FDA). Some manufacturers make unproven claims about the uses and efficacy of their products. There is also concern about the quality and safety of the products themselves.

One report by the Centers for Disease Control and Prevention (CDC) indicated that a number of people experienced negative unwanted side effects due to CBD products that contained synthetic CBD, although the products were not labeled as containing such ingredients.

Mislabeling appears to be a fairly common problem with CBD products. In one study, 70% of the CBD products that were sold online contained significantly more of the psychoactive ingredient THC than the label indicated.

Federal law prohibits the sale of products that contain more than 0.3% THC. States laws also vary, so you should always check with your state before buying CBD products online.

A Word From Verywell

If you do decide to take CBD to alleviate an acute or chronic condition, remember that the amount that you take will depend on a variety of factors. Finding the right dosage often takes some experimentation and adjustments. Starting with a low dose and then gradually increasing the amount you take until you achieve the desired effects is the best approach.

CBD oil for anxiety: can cannabidiol treat anxiety?

Cannabinoid specialist Dr Julie Moltke looks at the relationship between CBD oil and anxiety.

Cannabidiol – more commonly known as CBD – has a number of health benefits. Along with treating pain, epilepsy and acne, several studies have found that CBD oil is helpful for easing symptoms of anxiety. But is CBD oil something anxiety sufferers should consider over traditional treatment methods?

Cannabinoid specialist Dr Julie Moltke looks at the relationship between cannabidiol and generalised anxiety disorder:

What is CBD oil?

CBD oil contains a carrier oil with a CBD extract in one form or the other. Examples of typical carrier oils are MCT oil (coconut oil) or virgin olive. The CBD is added to the oil, either an isolate of pure 99.9 per cent CBD or as a full or broad-spectrum extract.

The broad-spectrum is often made from industrial hemp and contains CBD, along with all the other components of the plant. This includes terpenes (the essential oils giving cannabis its distinct smell) and other cannabinoids like CBG, CBN and THC. The broad-spectrum extract is a full spectrum, where all traces of THC has been removed.

Millions of people use CBD oil to deal with anxiety and stress due to our high-paced lifestyles.

In the UK THC is considered an illegal substance and therefore full-spectrum CBD oils are technically not allowed. Retailers that follow regulation will therefore only sell CBD oils based on either isolate or broad-spectrum. Some people will testify that full-spectrum oils work better because of what we call the entourage effect. This is the effects gained by all the cannabinoids and terpenes working together.

We still do not have enough clinical research to fully understand and support the entourage effect, and at the end of the day, it is down to the consumer to decide which product they feel most comfortable with.

How does CBD oil work?

Millions of people use CBD oil to deal with anxiety and stress due to our high-paced lifestyles. Researchers have investigated this association between CBD and anxiety reduction in a well-known study from 2011. In a gold standard double-blinded placebo-controlled randomised clinical trial patients with social anxiety disorder (SAD) were either given a dose of CBD or a placebo. They then had to do a social speaking simulation and their anxiety levels measured by different parameters were assessed.

People who had received CBD showed significantly lower anxiety levels than participants who had been given a placebo. The ways CBD work in the brain are complicated and still to be further investigated but there is evidence to suggest that CBD might even work against depression and addictive disorders.

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How does CBD oil ease anxiety?

CBD works by interacting with one of the body’s own regulatory system called the endocannabinoid system (ECS). We have endocannabinoid receptors almost everywhere in the body and it is part of our nervous system. We find them most abundantly in the brain but also in the gut, reproductive system, bones and immune cells.

CBD works by interacting with one of the body’s own regulatory system called the endocannabinoid system.

The ECS plays an essential role in keeping the body within a narrow range of operating conditions and controls important functions like mood, memory, stress, sleep, behaviour, appetite, pain, immune function and reproductive health. In the body we naturally produce chemical substances called endocannabinoids which binds to the endocannabinoid receptors and regulate all the above functions – the endocannabinoid system holds an important role in keeping us healthy and happy.

CBD can also bind to these receptors and active the ECS, thereby regulating the same functions. If this seems a bit too geeky all you need to remember is that CBD works a bit like social media. It acts everywhere and controls everything.

How does CBD oil ease anxiety?

As described above CBD works with the endocannabinoid system to produce some of the effects that people report, but CBD is also binding to other receptors in the brain like the serotonin (5HT)1a receptor. Serotonin deficiency is associated with depression and other psychiatric disorders and it is likely that the effects CBD has on mood and anxiety are related to this interaction.

The ways CBD work in the brain are complicated and still need to be further investigated, but there is evidence to suggest that CBD might even work against depression and addictive disorders.

What is the best CBD oil dosage for anxiety?

In the study mentioned above the participants were given a one-time dose of 600 mg CBD. This is a very high dose which I would not recommend outside a clinical setting. If you haven’t tried CBD before I would start low and then slowly increase the dose.

Starting with 5 mg twice a day and eventually, you might end at 50 mg twice a day. As everyone reacts different to CBD, one person might feel symptom relief with a dose of 10 mg per day and others will need 200 mg.

Many people like to use a vape for acute anxiety as it works very quickly and this might be useful if you suddenly feel anxious in a crowded space or other acute situations.

Does CBD oil have any risks?

The World Health Organisation has stated that CBD is safe and with no addictive potential. In a 1000 mg CBD, 30 ml bottle, a full 1 ml pipette contains 33 mg CBD. This means that 1 drop contains a bit more than 1,5 mg CBD.

Most people take between 10-100 mg CBD per day which is thought to be completely safe. One study showed that when you take doses of CBD above 1000 mg you might see a small effect on liver enzymes but this dose is uncommon and not recommendable. If you have any doubts, consult your doctor.

⚠️ If you’re taking other medication for anxiety or any other condition, it is important that you consult with your GP before trying CBD oil.

What’s the safest way to purchase CBD oil?

It is definitely of the highest importance to purchase your CBD oil from a trusted source. My advice to a new consumer is to ask a lot of questions. Ask about the labelling, the labelling is not always clear, and sometimes even I get confused. If it says, 200 mg on the label is it then 200 mg of pure CBD or is it CBD plus a mixture?

It is definitely of the highest importance to purchase your CBD oil from a trusted source.

As brands cannot suggest serving size, it is good to know what you are looking for and do your background research when you want to find the right product. Ask questions like do they quality test their products and what are the quality standards. All brands should use third-party testing.

Personally, I use different products throughout the day. At the moment I use a calming oil before going to sleep. I always liked to drink chamomile tea while reading a few pages in a book, as it makes me really calm before going to bed. I also have no phones on the bedside table and no computers one hour before bedtime. I recently added this oil by Yuyo Botanics to my evening routine and I take 1 full pipette which is approx. 30 mg cannabinoids one hour before going to bed.

Netdoctor top pick: we love Grass & Co’s Ease CBD Hemp Oil, a citrusy blend of CBD, ginger, turmeric and orange.

Dr Julie Moltke MD – Cannabinoid specialist Dr Julie Moltke qualified as a Doctor at Copenhagen University of Medicine and studied at Karolinska University, Stockholm and Pierre & Marie Curie University, Paris.

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