Can my Dog take CBD Oil While Taking Other Medications?
With the pet CBD market industry exploding globally, it’s no surprise that we need to look out for any drug interactions. What many people don’t know is that dog CBD oil can interact with other medications by either enhancing the effect, or by interfering with the metabolism of some.
In this blog, we’ll discuss why it’s important to consult with your veterinarian first before using CBD pet products.
Not only is this important so that you can get a proper diagnosis for a medical condition, but your veterinarian will be able to discuss any possible side effects if CBD is used together with other pet meds.
Here’s what you need to know to fully protect your pet, and to make sure that there are no drug interactions.
CBD can alter the way your dog processes certain medications
Yes, although cannabidiol (CBD) is a natural supplement that is beneficial for numerous health conditions in pets, as well as for chronic pain, insomnia, depression , and anxiety, CBD does have the potential to interact with certain medications.
CBD is derived from the hemp plant, yet it can also come from the marijuana plant. CBD hardly ever contains delta-9-tetrahydrocannabinol (THC), which is the compound that gives marijuana its “high” effect. High-quality CBD is non-toxic and considered safe for pets and humans alike.
There are almost no side-effects, apart from those coming from a low-quality CBD oil that may contain contaminants. It’s always best to look out for the compromised quality of some CBD oils.
You’ll need to discuss with your veterinarian all supplements, over-the-counter meds and prescription meds that your pet may be taking. Today research continues to demonstrate how effective CBD oil is for pets, yet one still needs to examine how it can interfere with the metabolism of pet meds and other supplements.
Benefits of CBD Oil for Dogs
Cannabidiol (CBD) extract is quickly gaining popularity as a natural alternative for managing pain, inflammation, and a variety of medical conditions, including epilepsy. However, recent reports have called into question the safety of CBD when used together with other pet meds. It’s also good to note that using a compromised quality or low-quality CBD oil raises the risk of side effects.
A recent 2019 study by the University of Korea, demonstrates that the CBD anti-cancer protein shows potential in killing tumor cells. The researchers tested the synergistic effect of CBD with a cancer destroying protein called TRAIL. (TNF related apoptosis- inducing ligand.)
The study concluded that TRAIL and CBD created apoptosis separately in colorectal cancer cells. The researchers also found that together, both reduced cancer cells a lot. “ To the best of our knowledge,” they wrote, “this is the first report that cannabidiol induces significant TRAIL-induced apoptosis of colorectal cancer cells,” noting that earlier reports suggested that a different protein response was responsible for cancer-cell death.” via MDPI Journals.
FDA & CBD
The FDA has also tested the chemical content of cannabinoid compounds in some of the products, and many were found to not contain the levels of CBD they claimed to have. We have also heard reports of CBD potentially containing contaminants (e.g., pesticides, heavy metals); we are looking into this.
Some cannabis products are also being marketed as pet food and health products for animals. The FDA has not approved cannabis for any use in animals and recommends pet owners talk with their veterinarians about appropriate treatment options for their pets.” via FDA, 2019.
Blood Pressure and CBD Oil
High doses of CBD oil may potentially drop blood pressure resulting in lightheadedness and possibly dizziness in people. It’s always best to consult with your veterinarian for the best advice prior to purchasing a CBD product. That said, the positive side of CBD oil use is that it may be good for patients with high blood pressure. CBD together with regular exercise and a healthy diet help to regulate hypertension.
A 2017 study by Dr. K Jadoon on CBD and its effects on blood pressure demonstrated the following:
The study concludes that “acute administration of CBD reduces resting BP and the BP increases stress in humans, associated with increased HR. These hemodynamic changes should be considered for people taking CBD. Further research is required to establish whether CBD has a role in the treatment of cardiovascular disorders.”
CBD Oil Interacts with Anti-Seizure Meds
A study researching CBD interactions with seizure meds in people added that “ Because all of the participants are also taking other seizure drugs while they are receiving the investigational therapy, investigators checked the blood levels of their other seizure drugs to see if they changed. “With any new potential seizure medication, it is important to know if drug interactions exist and if there are labs that should be monitored while taking a specific medication,” said lead author Tyler Gaston, MD,” via Science Daily.
Dr. Gaston and her colleagues found that there were significant changes in levels of the drugs clobazam (and its active metabolite N-desmethylclobazam), topiramate, and rufinamide in both adults and children, and zonisamide and eslicarbazepine in adults only.
Except for clobazam/desmethylclobazam, however, the drug levels did not change outside of the normally accepted range. In addition, adult participants in the study taking clobazam reported sedation more frequently.
Additionally, when seizure patients were using valproate, they added that “Tests also showed that participants taking valproate and CBD had higher ALT and AST (liver function tests) compared with participants not taking valproate.
Very high ALT and AST indicate abnormal liver function, but significant ALT and AST elevation occurred only in a small number of participants (4 children and 1 adult), and the levels returned to normal after discontinuation of valproate and CBD.”
The study concludes that “The findings emphasize the importance of monitoring blood levels of antiepileptic drugs as well as liver function during treatment with CBD. “
A perception exists that since CBD is plant based, that it is natural and safe; and while this may be mostly true, our study shows that CBD, just like other antiepileptic drugs, has interactions with other seizure drugs that patients and providers need to be aware of,” said Dr. Gaston.”
CBD as a natural supplement does not cause a “high” in pets, but may cause a reaction when used together with anti-seizure meds. Cannabinoids have been shown to inhibit cytochrome P450 enzymes by using up these enzymes, and by inhibiting how other enzymes work.
When cannabidiol oil is consumed by dogs in large amounts, a large group of enzymes may be altered in the same way that grapefruit alters enzymes.
Most pet meds are metabolized in the liver via certain enzymes that are made in it. CBD works in the same way that grapefruit does, and may use up all the enzymes and also alter the effectiveness of pet meds.
NSAIDs and Corticosteroids
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are a class of drugs commonly used to control pain and inflammation in dogs. NSAIDs help many dogs lead a life that is more comfortable for them, but what about interactions with CBD oil? CBD oil has the potential to make pet meds less effective.
That said, pet parents should take every precaution to ensure that there are no interactions with any of their pet meds or supplements, and even NSAID’s, corticosteroids, pet herbal supplements and vitamins. The potential for adverse reactions will also depend on the body chemistry of your pet and the dose of the prescription or supplement.
Administer CBD oil 2 hours before or 2 hours after giving pet meds or supplements.
NSAID’S include the following:
Meds like Gabapentin when taken together with CBD can cause lethargy in pets. It’s important to discuss CBD use with your veterinarian prior to administering.
Common corticosteroids include the following:
The most common symptoms when using these are gastrointestinal issues like lack of appetite, vomiting, diarrhea, and even ulcers. We all know that pets cannot take both NSAID’s and corticosteroids at the same time, but what about cannabidiol oil and NSAID’s and corticosteroids?
CBD oil can also enhance the effectiveness of certain drugs and one may be able to lower the dose of pet meds or therapy when using CBD oil. Pet meds that are used for pain relief need to be administered carefully when using them together with CBD oil.
CBD Oil for Dogs: What You Need to Know
As with any pet wellness trend, when it comes to CBD oil for dogs, there’s a lot of information floating around the internet, and it’s difficult to know what’s accurate and what’s exaggeration. Of course, you want to do what’s best for your pup, which leads to the question: What do I need to know about CBD oil for dogs?
The AKC’s Chief Veterinary Officer, Dr. Jerry Klein, explains what CBD oil is, what it does for dogs, and its safety concerns and potential side effects.
What Is CBD Oil?
CBD, or cannabidiol, is a compound found in cannabis and hemp. Dr. Klein says it is essential to note that in most cases, CBD oil does not contain delta-9-tetrahydrocannabinol (THC), the compound that gives marijuana its psychoactive properties. In fact, most CBD products are derived from hemp and not from marijuana.
How Does CBD Affect Dogs?
Currently, there has been no formal study on how CBD affects dogs. What scientists do know is that cannabinoids interact with the endocannabinoid receptors located in the central and peripheral nervous systems, which help maintain balance in the body and keep it in a normal healthy state.
What Dog Health Problems Can CBD Oil Treat?
While there’s no definitive scientific data on using CBD to treat dogs, there’s anecdotal evidence from dog owners suggesting it can treat pain, especially neuropathic pain, as well as helping to control seizures.
According to Dr. Klein, CBD is also used because of its anti-inflammatory properties, cardiac benefits, anti-nausea effects, appetite stimulation, anti-anxiety impact, and for possible anti-cancer benefits, although there’s no conclusive data on this use.
The AKC Canine Health Foundation (CHF) is sponsoring a study through the Colorado State University’s College of Veterinary Medicine and Biomedical Sciences to evaluate the use of CBD in treatment-resistant epileptic dogs. The CHF hopes that this will be the first study to gain scientific data on the use of CBD in dogs with this condition.
Possible Side Effects of CBD in Dogs
While there’s no scientific data on the side effects of CBD usage for dogs, there are potential side effects based on how CBD affects humans. To minimize any potential side effects, make sure you are following the proper dosage.
- Dry mouth: Research has shown that CBD can decrease the production of saliva. For dogs, this would manifest as an increased thirst.
- Lowered blood pressure: High doses of CBD have been known to cause a temporary drop in blood pressure. Even though the drop is small, it might create a brief feeling of light-headedness.
- Drowsiness: Dog owners have used CBD to treat anxiety. The calming effect of CBD can also cause slight drowsiness, especially when using higher doses.
Risks of Using CBD Oil for Dogs
The safety and risks of using CBD for dogs have not yet been researched. The U.S. Food and Drug Administration has not approved CBD and has not issued a dosing chart. Therefore, we do not know what size dosage would be toxic. Any medication or supplement carries the risk of a reaction. It is always advisable, when giving your dog something new, to start out with small amounts and then closely monitor the effects. And always check with your veterinarian first.
CBD Products on the Market
If you and your veterinarian decide that you should try CBD as a treatment for your dog, there are a few things to keep in mind when purchasing CBD oil. Not all oils are the same; you’ll want high-quality CBD oil to have a better chance of it working.
- Look for organic. If the CBD oil is not organic, it at least should not contain pesticides, fungicides, or solvents.
- Don’t only shop based on price. Higher quality and purity are usually associated with a higher cost. A cheaper option could contain toxic substances such as pesticides, herbicides, or heavy metals. Make sure your CBD oil is free of additives.
- Get the analysis. The manufacturer should provide a certificate that certifies the amount of CBD that is in the product. Many CBD products contain only small amounts of CBD. You’ll also want to make sure there is little or no THC in the product.
- Buy CBD as a liquid. You can buy dog treats containing CBD, but the best form to administer is an oil or tincture. This way, you can adjust your dog’s dose drop by drop.
The CBD Wellness Trend
Why are we hearing so much about CBD oil now? Dr. Klein points to the legalization of marijuana in many places, which has triggered interest in potential health benefits of marijuana-related products. “We are likely to see continued interest in CBD and an increase in research about its uses and efficacy in the coming years,” he says.
Learn more about the CBD study funded by the Canine Health Foundation.
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Can Humans Use Pet CBD Oil?
CBD oil has recently made headlines in newspapers, magazines, and social media athlete pages. It is repeatedly touted as a versatile supplement that could help improve the quality of your (and your pets) life both immediately and long term.
CBD is an increasingly popular ingredient in many health and wellness circles. There has been a lot of buzz about CBD oil in the last few years, but what exactly is CBD oil?
What is CBD Oil?
First, the acronym ‘CBD’ stands for cannabidiol. Cannabidiol is a naturally-occurring chemical compound found in the flowers, leaves, and stalks of the hemp plant.
Hemp oil is NOT marijuana, but it’s one of many cannabis plants. It is a close cousin of cannabis, but hemp does not contain THC, or tetrahydrocannabinol. THC is the chemical compound in cannabis that causes you to feel high.
CBD oil is made by isolating the individual CBD compounds through extraction and then distilling them in alcohol to remove impurities. They’re usually then suspended in a carrier oil. Plants have been used by humans throughout history to improve physical and mental health and to mitigate the damage to our bodies by disease.
Specific plants have long been used in medicine, magic, and folklore, and many sets of prehistoric remains have been found with ritualistically-carried herb and plant matter on their bodies and in their camps.
The discovery of the endocannabinoid system (ECS) provided solid biologically-backed evidence of what humans have known since we were barely human: that plants have a profound ability to control, enhance, and heal our bodies and our minds.
The endocannabinoid system (ECS) plays an incredibly important role in creating memories, stabilizing mood, and regulating hormone production. It can help your brain and body learn to adapt to stress, both chronic (like work deadlines and traffic) and acute stress (particularly helpful in survival situations).
It can control the ability (or inability) to reproduce. It can affect all our body’s primary functions including depth and quality of sleep, digestion and proper absorption of nutrients, and the way our immune system protects us from illness.
An insensitivity to CBD could play a role in chronic illness and may point to how and why our bodies suddenly develop diseases like cancer.
When taking CBD oil, the CBD oils essentially encourages our bodies to work with our endocannabinoid system to maintain internal homeostasis, which is the balance across all our major regulatory systems (the nervous system, for example, or circulatory system).
It helps our body synchronize the chemicals and hormones we produce and use every day, can help manage many medical conditions (including anxiety, depression, epilepsy, cancer, and chronic pain and inflammation), and improves overall health and well-being.
Many people say they feel better, younger, and in better general health when regularly using quality top-tier CBD oil.
CBD is safe, effective, and easily metabolized by everyone. It is virtually impossible to take too high of a dosage with pet CBD oil or human CBD oil. There is no risk of becoming chemically dependent on (or addicted to) CBD oil. No serious side effects have been reported. On rare occasions mild diarrhea or slight drowsiness has been linked to high dosages.
How Do You Use CBD Oil?
The CBD oil that consumers can purchase in stores and online come in many forms: tinctures, capsules, and edibles.
Tinctures are often used sublingually, which means they are placed under the tongue for 60 seconds and then swallowed, and can be absorbed into the body significantly faster than capsules or edibles.
Sublingual CBD oil can provide by far the most efficient relief : you could start feeling the effects of a CBD oil tincture in as little as 10 or 15 minutes versus the 30 to 45 minutes, on average, for other methods, particularly those that require digestion.
The average dosage of CBD depends on what you need it for. For example, pet owners and their dogs won’t require the same dosage of CBD. CBD dosage will be lower for a dog compared to human consumption. Human grade CBD and high quality CBD yields many benefits when the proper dosage is administered.
The dosage for pets will be based on the pounds of body weight. With a dogs or cats, the difference between CBD oil for pets and humans will differ. CBD products will tell you how big your dosage should be. A heavier pet will require a high dose of quality CBD compared to a smaller-sized pet, which will require a lower dose.
Even 10 pounds of body weight can make a major difference in how much CBD to take. A good idea is to look at the labels on pet products to better understand the right dose.
For example, before you give CBD to your dog, check with your vet. The veterinarian your dog sees on a regular basis can give you better information than the label on a CBD bottle. Ask your vet is it’s safe for your dog to take CBD before giving it to your pup!
Remember that CBD is not intended to diagnose treat cure health related problems or prevent any disease. Instead, it’s used as one of many dietary supplements that minimize the pain caused by related symptoms.
CBD oil for pets comes in a various forms. There are two types of CBD oil available for pets: CBD isolates and full-spectrum CBD oil.
THC is the psychoactive chemical compound in cannabis. THC is illegal in a number of places and THC is incredibly toxic to animals. It absolutely should not be present, in any amount, in pet-friendly products. Only buy THC-free CBD oil for pets!
Of course, the most popular (and most widely available) CBD products right now are the oil tinctures and capsules or pills. These provide an easy, effective way of getting CBD oil into your body, they’re easy to fit into your day, and they make dosing simple. Many times you can find a pill with the exact dosage you need so there is no measuring or math needed!
**Remember to check the ingredients list and the label for any other information before using your oil.**
Can Humans Take Pet CBD Oil or Not?
Have you ever asked yourself, “Can humans take pet CBD oil or not?” It’s a reasonable question! In short, the answer to “Can humans take pet CBD oil or not?” is yes! Human CBD oil and pet CBD oil are virtually interchangeable. Dogs, humans and pets can all take CBD oil.
So, what CBD oil can humans take?
Let’s answer the question of what CBD oil can humans take!
When thinking about the answer to the question, “Can humans take pet CBD oil or not?” it helps to remember what CBD is used for. Animals can suffer from the same medical conditions that humans can and the symptoms can be treated with high quality CBD oil. So if anyone ever asks you, “Can humans take pet CBD oil or not?” you’ll know what to say!
Arthritis, lack of appetite, anxiety, cancer affect pets and humans. Pet CBD can be just as safe and effective for your pets as it is for you! There’s not much difference between CBD oil for pets vs humans CBD.
CBD affects everyone very similarly. Even the most primitive animals have cannabinoid receptors! In humans and pets, cannabinoid receptors make it possible for them to consume CBD products and reap the benefits of CBD. It’s like a digestive system for CBD.
Most CBD oil products are safe for both humans and pets. However, you might be confused about which oil can humans take because of pet CBD labels. CBD oil for dogs will explicitly say it’s CBD oil for dogs because of marketing. Likewise, human CBD oil is marketed for human consumption, so CBD oil for humans will be clearly marked. Human CBD is subjected to more stringent regulations than pet CBD oil and pet CBD products.
Even so, CBD products are for everyone. Humans can take pet CBD oil or human grade oils, and pets can take CBD oil for humans. Like all substances, CBD products for pets must adhere to more rigorous testing procedures as evaluated by the FDA or Federal Drug Administration. CBD oil products are subjected to stricter labeling guidelines by the FDA as well. If a product is not approved by the FDA then you shouldn’t buy it. The FDA has these guidelines in place for a reason!
Check with your doctor or veterinarian to see if you and your pet are candidates for cannabidiol use. It could be the invigorating, revitalizing, life-changing solution modern humans and pets need to function at their peak!