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Best cbd vape oil for weight loss

CBD Oil for Weight Loss – June 2022

Although many recognize CBD for its anti-seizure, anti-inflammatory, pain-relieving, neuroprotective, anti-anxiety, and antidepressant properties(7), recent studies have also suggested its promising potential in aiding individuals who need to lose weight and excess body fat.

One of the growing public health concerns leading to a need for weight loss is obesity and the accompanying metabolic disorders.

Obesity is a disease that occurs when the human body incurs an excessive amount of fat.

One way to know if an individual has become obese is if their body mass index (BMI) increases to 30 or higher. However, this method has not always been reliable as BMI cannot correctly measure the amount of body fat one has.

Many factors can contribute to obesity, from genetics to imbalances in metabolism and hormones. Diet also plays a big part in the development of obesity.

When individuals consume too many calories and fail to burn these through exercise and normal daily activities, the body begins storing excess calories as fat.

Obesity should not be reduced to a mere cosmetic issue.

Obesity, when left untreated, can lead to other severe medical conditions such as diabetes, heart disease, high blood pressure, and even cancer (8 ) .

Weight loss is foremost the best remedy for obesity. The change to a healthy diet and an increase in physical activity should help obese individuals lose weight.

Studies also suggest that CBD oil may help in combating obesity by promoting weight loss.

One significant study investigated how the administration of cannabinoids, like CBD, could affect the appetite of rat subjects (9 ) .

In the study, it was stated that tetrahydrocannabinol (THC), another famous cannabinoid, could increase appetite and food consumption in animals.

However, the researchers noted that few studies have verified if other cannabinoids, like CBD, had the same effects.

Together with the cannabinol (CBN), the researchers administered CBD to adult male rat subjects.

Results showed that while CBN increased the rats’ food consumption, CBD was able to reduce it significantly.

Researchers noted CBD’s possible anti-obesity effects but suggested that further studies were needed.

Another critical study published by the Molecular and Cellular Biochemistry scientific journal found that CBD had the potential to prevent obesity by promoting the “fat browning” process (10 ) .

Brown fat, or brown adipose tissue, is a type of fat used to produce heat. When activated, it burns calories.

On the other hand, white fat, or white adipose tissue, stores energy and is more prevalent in adults.

The fat browning process occurs when the usual white fat cells (stored energy) in fatty tissue are converted into fat brown cells.

Brown fat is seen as a valuable target for promoting weight loss and a potential remedy for obesity and diabetes, as it burns excess calories (11 ) .

The researchers also discovered that CBD was also able to advance the breakdown of adipocytes (fat cells) and its generation process by lessening the expression of proteins involved in it.

Another study found CBD to reduce rat subjects’ body weight gain due to CB2 receptors (12 ) .

The research cited the role of the endocannabinoid system (ECS) in regulating food intake and energy balance.

The ECS is vital in activating CBD’s therapeutic effects on the human body’s metabolism, which is responsible for converting food to energy.

The rat subjects were given CBD injections twice a day for 14 days. The researchers found that CBD was able to significantly reduce the rats’ body weight gain, with the higher dose being more effective.

Research has also linked a worsening metabolic syndrome (high blood pressure and blood sugar, excess body fat around the waist, and unstable cholesterol levels) to the development of hepatosteatosis or non-alcoholic fatty liver disease (NAFLD) in individuals with obesity (13 ) .

The same study also discovered that individuals with NAFLD were prone to develop insulin resistance and heart conditions.

NAFLD develops when fat amasses in the liver of individuals who consume little to no alcohol, and causes inflammation. NAFLD is also referred to as fatty liver (14 ) .

Available treatments for NAFLD are few, which prompted researchers to investigate cannabinoids, like CBD, as a potential alternative remedy.

In a 2015 study, researchers used CBD to improve insulin sensitivity and its effects on the levels of lipid or cholesterol in the body (15 ) .

They found that CBD, along with another cannabinoid called tetrahydrocannabivarin (THCV), was able to reduce cholesterol levels in obese mice and zebrafish.,

This finding suggested that CBD could inhibit the development of NAFLD.

Both the cannabinoids were also able to lessen the buildup of triglycerides within the liver, one of the main components of natural fats and oil.

It also improved the subjects’ resistance to insulin.

The researchers concluded that CBD’s properties posed a potential new treatment for obesity and metabolic diseases such as NAFLD.

Because it interacts with the endocannabinoid system, CBD, along with THCV, was also found to lower cholesterol and blood sugar levels in mice with type 2 diabetes (16 ) .

Researchers concluded that cannabinoids, like CBD, had promising potential in controlling blood sugar levels of patients with type 2 diabetes.

Meanwhile, another study administered CBD treatment to female mice that were not obese yet prone to diabetes for five days a week for a total of four weeks (17 ) .

The researchers stopped administering CBD treatment after this period.

By the time the subjects were 24 weeks old, they had found that CBD was able to reduce the development of diabetes in the mice significantly.

Also, one significant study concluded that CBD had the potential to alleviate the symptoms of insulin resistance, type 2 diabetes, and the metabolic syndromes associated with it (18 ) .

However, some study results have contradicted evidence pointing to CBD’s anti-obesity properties.

A 2014 research, published in the official journal of the Polish Physiological Society, examined the effects of CBD on rat subjects put on a high-fat sugar diet (19 ) .

Researchers cited the consumption of fats and sugars as one of the leading causes of obesity in humans. They investigated whether CBD could impact the food intake and body weight of the rat subjects.

When injected with CBD, the rats put on a high-fat diet developed an increase in body weight, despite their decreased food intake.

Meanwhile, the rat subjects given a free choice diet experienced no notable changes in body weight or food consumption.

Another study also examined the effects of CBD and other cannabinoids on the food intake of mice subjects (20 ) .

They found that the administration of THC was able to increase the mice’s food consumption. At the same time, CBD did not affect food intake or activity.

However, another study explains that this result could be due to the low dosage of CBD administered to the mice (21 ) .

The Cannabis sativa plant (where CBD and THC come from) was also known to cause appetite stimulation in its users (22 ) , a phenomenon referred to as munchies.

One study found that 786 adult Inuits who used cannabis had a significantly lower chance of developing obesity (23 ) .

Despite all this, research investigating the effects of CBD on appetite, weight, and metabolism is few, with the majority being animal studies.

Most of the information supporting CBD’s effectiveness in weight loss and appetite suppression is also anecdotal.

Most of the positive feedback is from individuals who have self-administered CBD oil as part of their daily regimen to achieve weight loss.

However, CBD is not a miracle cure for obesity, diabetes, heart disease, or any health conditions related to it.

Individuals should consult with health professionals if they wish to pursue CBD as an aid in weight loss.

Nevertheless, the anti-obesity and anti-diabetes effects of cannabinoids, including CBD, should be pursued.

These cannabinoids possess potential as an alternative weight loss aid, as evidenced by research.

How CBD Oil Works for Weight Loss

Various studies have attributed CBD’s weight loss and appetite suppressant effects to its special relationship with the endocannabinoid system (ECS).

The ECS plays a crucial role in regulating various bodily processes, including metabolism, appetite, and body weight regulation (24 ) .

In particular, the ECS plays an essential role in amassing fat used for energy (25 ) .

When the ECS becomes unbalanced or overactive, it can promote fat accumulation and even advance cardiovascular risks that lead to type 1 and type 2 diabetes.

To explain, the ECS is composed of three main components: cannabinoid receptors, endocannabinoids, and the enzymes that allow for its breakdown and synthesis.

CB1 and CB2 are the two primary receptors of the ECS.

CB1 receptors exist mostly in the brain and nervous system. However, they also exist in tissues and the endocrine gland. In contrast, most CB2 receptors are located in the immune system.

CB1 receptors play a crucial role in regulating appetite, metabolism, and body weight (26 ) .

Specifically, blocking CB1 receptors help reduce body weight and food intake.

Meanwhile, stimulating CB2 receptors limit inflammatory responses, produce anti-obesity effects through appetite suppressant actions, and limit body weight gain (27 ) .

Receptors are also responsible for the previously mentioned fat browning process, where white adipose tissues (white fat cells) are transformed into brown adipose tissues or brown fat cells.

Fat brown cells are a potential target for promoting weight loss in obese patients.

On the other hand, endocannabinoids (endogenous cannabinoids) are neurotransmitters that act as signals for the body to take action.

When they bind with either CB1 or CB2 receptors, specific effects are activated, depending on which receptor is triggered.

CBD or cannabidiol can also bind with CB1 or CB2 receptors since it is a phytocannabinoid.

While endocannabinoids originate from the body (hence the term ‘endogenous’), phytocannabinoids (phyto meaning from the plant) are cannabinoids naturally found in the Cannabis sativa plant.

Since CB1 receptors also exist in tissues and the endocrine gland, CBD’s interaction with these receptors can help reduce appetite and reduce overeating problems experienced by certain individuals.

Studies imply that CBD can block CB1 receptors, which is the reason for its anti-obesity effect (28 ) .

On the other hand, a study that administered CBD to rats found CBD’s interaction with CB2 receptors to reduce the subjects’ body weight (29 ) .

Researchers concluded that CB2 receptors played a crucial role in body weight regulation. However, further studies should be conducted to support this evidence.

CBD is only one of the hundreds of phytocannabinoids naturally occurring in the Cannabis sativa plant.

Another one is THC or tetrahydrocannabinol, which is popular for its psychoactive properties that induce a euphoric “high” effect in its users.

CBD, on the other hand, is non-psychoactive because it comes from the hemp plant, one of the varieties of the Cannabis sativa plant.

Industrial hemp plants contain less than 0.3% THC. Hemp extracts like CBD oil and other hemp products are used for their numerous health benefits.

The Pros and Cons of CBD Oil for Weight Loss

  • CBD oil is considered safe and non-toxic for both humans and animals. Studies found CBD to contain little to no adverse effects (30 ) .
  • Chronic use and intake of high doses of CBD appear to be well-tolerated by humans (31 ) .
  • CBD oil has been given generally positive feedback by various individuals, health professionals, and health organizations, including WHO (32 ) .
  • CBD is non-psychoactive, meaning it cannot give its users a euphoric high, unlike THC.
  • The director of the National Institute on Drug Abuse (NIDA) Nora Volkow claims that CBD is non-addictive (33 ) and that it is safe for daily use.
  • Due to CBD’s popularity in the United States, various CBD products for weight loss are available on the market. There are CBD tinctures, oil drops, gummies, capsules, and soft gels from which users can freely choose.
  • The 2018 Farm Bill allowed for industrial hemp farming and the production of hemp products derived from it. However, restrictions still apply.
    Industrial hemp plants must contain less than 0.3% THC, and cannabis products and compounds are still regulated by the U.S. Food and Drug Administration (FDA) (34 ) .
  • CB1 receptors, when activated, can enhance appetite and food intake.
    Meanwhile, blocking CB1 receptors can suppress appetite. However, this action was also seen to enact adverse psychiatric side effects (35 ) .
    CBD blocks CB1 receptors, which explains its anti-obesity effects (36 ) . However, due to the previously mentioned adverse psychiatric effects, further caution is needed when using CBD oil for weight loss.
  • Limited evidence supports the effectiveness of CBD in promoting weight loss and as an appetite suppressant. Most of the available research were animal studies.
  • CBD has shown no remarkable adverse effects on various human and animal studies. However, some notable side effects may include drowsiness, dry mouth, diarrhea, and fatigue (37 ) .
  • Certain CBD products contained labeling inaccuracies, with some products containing more CBD, while others lesser amounts than stated (38 ) .

How CBD Oil Compares to Alternative Options for Weight Loss

Common natural options for losing weight include Ayurvedic medicine, essential oils, and natural weight loss supplements.

Ayurvedic medicine, or Ayurveda, is an ancient Indian medical system that emphasizes a natural and holistic approach to promoting physical and mental health (39 ) .

Ayurvedic treatment includes the use of plants, minerals, diet, exercise, massage, pressure point treatment, and lifestyle changes to bring balance to mind, body, and spirit.

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Evidence backing the effectiveness of Ayurvedic medicine in Western medical journals are few. However, like CBD oil, many individuals have used Ayurveda as a natural means to lose weight.

Ayurveda uses various plant extracts and herbs to promote overall health and well-being. Similar to CBD oil, essential oils from plant extracts have also been used to aid weight loss.

One study reviewed various literature investigating the effectiveness of essential oils as anti-obesity agents (40 ) .

The researchers reviewed existing literature on essential oils from the year 2000 to 2015. They found that only one study specifically used essential oils to combat obesity.

However, the lone study’s data was not enough to support the claim that essential oils were effective in reducing fat accumulation in obesity.

Many dietary weight loss supplements also include plant extract as ingredients.

The U.S. National Institutes of Health Office of Dietary Supplements (ODS) published a fact sheet about dietary weight loss supplements.

The fact sheet revealed that common weight loss supplements contained African mango, bitter orange, caffeine, raspberry ketone, green tea, and green coffee bean extract (41 ) .

However, in the same fact sheet, the ODS states that evidence supporting dietary supplements’ abilities to reduce body weight and promote weight loss is inconclusive at best.

The ODS still recommends a healthy diet and an increase in physical activity as the best ways to lose weight.

Like the previously mentioned natural weight loss options, CBD oil also works best when combined with a healthy diet, lessened intake of calories, and physical activities.

How to Choose the Best CBD Oil for Weight Loss

Users looking to use CBD for weight loss should know what to look for when selecting CBD products.

  • CBD products are labeled as either full-spectrum CBD, broad-spectrum, or CBD isolate.

Full-spectrum CBD contains the majority of the active cannabinoids found within the hemp plant, including terpenes and flavonoids. It also contains natural ingredients and compounds such as Omega-3 and Omega-6 fatty acids. When used, all of these components combine to produce the famed entourage effect.

Broad-spectrum CBD oil is essentially the same. However, it is marketed as being THC free as it contains less than 0.3% THC.

Meanwhile, CBD isolates contain pure CBD oil. These CBD products are suitable for those suffering from allergies to other components found in hemp extracts.

  • Be aware of the exact legal provisions surrounding the purchasing and use of CBD oil.

The 2018 Farm Bill has allowed for the selling and distribution of CBD products in various states.

  • Prioritize buying from sellers, and CBD brands that have organic, non-GMO CBD products as these are indicative of high quality.
  • Buy CBD products from only legitimate sellers. The majority of companies cultivate hemp from their farms or simply purchase from licensed industrial hemp producers. Users should know how their CBD oil was manufactured and packaged.
  • Check the certifications of CBD brands and sellers. CBD products must have certification codes, while companies must have a certificate of analysis (COA).
  • CBD brands and sellers must also have good manufacturing processes (cGMP) and third-party lab certificates of analysis for all batches of CBD oil produced.
  • Check CBD product reviews and customer feedback for each CBD product. Consider these as testimonials to the products’ performance.
  • Lastly, users should first consult with their health professionals before using CBD as an appetite suppressant or weight loss aid.

Weight gain and overeating may be symptoms of more significant diseases, to which CBD is not a verified treatment or cure.

It is up to the physician’s discretion on whether or not they are going to prescribe CBD as an additional remedy.

CBD Dosage for Weight Loss

There is yet to be a standardized and approved dosage chart for CBD use for weight loss.

Users are encouraged to first seek advice from medical professionals if they wish to use CBD oil to help lose weight.

However, the general rule for CBD dosage is to start with small initial doses and gradually increase in incremental amounts until the desired effect manifests.

Non-profit organization Project CBD states in an article that a prolonged, low dose therapy may be advantageous for those managing chronic symptoms and preventing the recurrence of disease (42 ) .

When in doubt, follow the dosing instructions as provided by the manufacturer of the CBD product purchased and consult with your physician.

Since no standardized dosage chart is available, CBD brands provide their dosage standard and charts.

Therefore, the safest route is to follow the provided dosage as per the product’s instructions.

How to Take CBD Oil for Weight Loss

There are many ways to administer CBD oil for weight loss.

Although topical CBD products are available, most CBD products for weight loss are taken by mouth.

CBD oil tincture dominates the market. Various oil drops and hemp extracts are applied sublingually (under the tongue) and swallowed after a few seconds.

Certain brands have flavored CBD oil products for those who do not enjoy the natural, earthy taste of hemp extracts.

CBD oil can also be dropped and mixed into food and drinks if the usual sublingual route is not preferred.

Select CBD oil products can also be repurposed for vaping. However, CBD vape juice is also available for this specialized method of administration.

Many users also claim that inhaling CBD through vape is more fast-acting than sublingual administration.

However, few studies have investigated the possible health impact of vaping CBD products.

One study investigated the effects of inhaling vaporized CBD to rat subjects, due to the prevalence of CBD vape products on the market (43 ) .

The researchers administered CBD to rats by letting the subjects inhale the vapor produced by an e-cigarette.

The researchers found that CBD lowered the subjects’ body temperature, inducing hypothermia. Inhaling CBD through vapor also produced dependency effects in the rats.

Non-profit organization Consumer Reports also found that several CBD vape users were hospitalized because of vitamin E acetate (44 ) .

Vitamin E acetate is a chemical used in diluting oils for vape products.

Meanwhile, one study published in the Canadian journal of respiratory therapy stated that the vaporization of cannabis was able to reduce the delivery of toxic byproducts that exist in cannabis smoke (45 ) .

The study mentioned that the vaporization of cannabis was less likely to be harmful than smoking.

However, it also noted that research on the long term effects of cannabis vaping had yet to be published, making it difficult to draw conclusions.

Researchers from Johns Hopkins Medicine also emphasized the importance of dosage when vaping cannabis products (46 ) .

CBD products for weight loss also come in the form of capsules, gummies, and soft gels.

It is a convenient way to take CBD, as it is in tablet or chewable forms.

Some individuals also prefer these products since it is easier to follow the dosing instructions.

CBD brands that offer these types of products instruct on taking one to two capsules a day.

Keep in mind that CBD is by no means a cure for obesity, diabetes, or any metabolic diseases that may cause one to overeat or gain excess body fat.

Users can take CBD as help for weight loss. However, individuals should first consult with a physician before self-administering for any signs or symptoms of medical conditions.


Various studies have documented the anti-seizure, anti-inflammatory, pain-relieving, anti-anxiety, and antidepressant effects of CBD.

However, individuals are also turning to CBD oil as an aid for weight loss.

Various studies have shown evidence for CBD’s anti-obesity and anti-diabetes properties. However, much more research is further needed to validate these findings.

There is no known harm in using CBD oil as an aid for weight loss.

However, it is not going to cure or treat obesity, diabetes, or any metabolic disorders that accompany the former.

CBD For Weight Loss: Can Hemp Oil Help You Lose Extra Weight?

Most people assume cannabis extracts increase hunger — instead of killing it. But this effect is linked to a different cannabinoid called THC (tetrahydrocannabinol), which is also the reason behind the psychoactive effects of marijuana.

CBD is different, it’s non-psychoactive, and has an entirely different set of effects on things like appetite and metabolism — both of which are heavily linked to weight gain and loss.

Numerous case-studies, as well as peer-reviewed research results, have indicated that CBD use is associated with reduced body mass index (BMI), lower body weight, and smaller waist circumferences.

This doesn’t mean you should ditch your diet and rely solely on CBD. You can, however, add CBD oil to your regime for improved results.

In this article, I’ll go over each aspect related to CBD and weight loss — and show you my top 3 CBD Oil brand recommendations.

How Can CBD Oil Help You Lose Weight?

The reason why people gain weight is straightforward.

You’re taking in more calories than you’re letting out.

However, our ability to burn fat is affected by a variety of factors, and compromised metabolism often derives from hormonal imbalances and changes in metabolic patterns, inflammation status, and the function of the endocannabinoid system.

Steady weight loss requires you to return your body to a healthy balance between the digestive, immune, and nervous system — and the ECS is a bridge between them all.

So, how can you modulate the endocannabinoid system with CBD? What does the research say about using CBD oil for weight loss?

Read on to learn about the latest studies.

1. Suppresses Appetite

Many CBD proponents say that the compound can help you lose weight by reducing appetite.

Most people link cannabis to appetite stimulation, as people who smoke weed tend to feel more hungry than usual. While it’s true that THC may induce hunger, CBD does not.

THC activates the CB1 cannabinoid receptors in the body, causing a range of effects, including increased appetite. However, according to a 2018 study, CB1 receptor antagonists may help reduce appetite and control obesity because they block off or “deactivate” the receptor.

While CBD doesn’t deactivate CB1 receptors directly, it may act on other molecules prompting to block them off. Shutting off these receptors may help curb the appetite and prevent overeating in some people.

An older animal study published in 2012 revealed that CBD administration to rats reduced their appetite. While plenty of anecdotal evidence supports the concept of CBD and appetite suppression, there have been no human trials in this subject yet.

2. Turns On Fat Browning in the Body

CBD advocates also claim that CBD can convert white (or bad) fat into brown fat, which may improve the body’s ability to burn calories.

White fat is responsible for increasing the risk of many chronic conditions, such as diabetes or heart disease, so the fat-browning process may also benefit you in other areas of health.

A 2016 study supports the claim about fat conversion. The scientists involved in that study found that CBD can influence how the body interacts with fat on many different levels.

Not only did CBD help turn white fat cells into brown fat cells, but it also caused a more efficient breakdown of fats within the body.

Brown fat cells are more active than their white counterparts. They burn off energy as heat, stimulating thermogenesis, and thus helping the body burn more calories.

3. Reduces the Risk of Metabolic Disorders

According to a 2018 study, obesity may trigger several metabolic disorders, such as high blood pressure, high cholesterol, and type 2 diabetes.

This happens through the overactivation of the CB receptors in the body. When CB1 receptors are overstimulated in the fat tissue throughout the body, this may contribute to obesity and the aforementioned metabolic symptoms.

Because CBD can block off the CB1 receptors, it might also reduce the risk of obesity. A review in Cannabis and Cannabinoid Research mentions some past studies involving CBD and metabolic factors, mainly in rodents.

For instance, people treated with CBD showed a reduction in cholesterol by 25 percent over time. Besides, the anti-inflammatory and antioxidant effects of CBD also decreased their blood sugar levels and improved markers for liver health.

4. Helps With Insulin Resistance

Insulin resistance is an almost inseparable feature of obesity and diabetes.

A healthy metabolic process follows a simple pattern:

  1. You eat food
  2. Blood sugar levels rise
  3. The pancreas releases insulin to move the glucose to the body cells
  4. The cells use glucose as an energy source

When your eating patterns constantly provide excess glucose, the system will go out of whack. As body cells are unable to withstand more glucose, they become resistant to insulin’s signaling to pump the simple sugar into the cell.

With dangerously high blood glucose levels, the pancreas begins to secrete even more insulin. In the end, the unusually intense production of insulin will cause glucose levels to plummet.

That’s why people suffering from insulin resistance tend to experience “blood glucose roller coaster,” feeling hungry and sluggish.

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Unhealthy metabolism follows this process instead:

  • You eat food
  • Blood sugar levels rise
  • The pancreas releases insulin to move glucose into the cells
  • Insulin doesn’t work
  • Blood sugar levels continue to rise
  • The liver steps in to convert sugar to fat to protect the body from high sugar
  • Your cells still want sugar for energy and trigger the appetite
  • The process continues

A 2018 study showed that cannabinoids like THC, CBD, and CBN enhance cells’ potential to absorb glucose, performing even better than metformin, a commonly prescribed pharmaceutical for high sugar levels.

If we can absorb the sugar from the blood when we need it, we convert less to fat and feel hungry less often.

5. May Fix Mitochondrial Dysfunction

Mitochondria act as the energy factories for cells. When insulin brings glucose to the cells, the mitochondria use it to produce the “fuel” for the body and brain. But when insulin resistance occurs, the mitochondria’s capabilities are impaired as well.

Mitochondrial dysfunction occurs in most conditions that include imbalanced glucose levels and maybe a serious contributor to cancer. Healthy mitochondria, in turn, are guaranteed to provide long-lasting vitality.

A 2016 lab study investigated the impact of CBD on the metabolic function of fat cell cultures. The study recorded a significant improvement in mitochondrial function with the administration of CBD.

6. Reduces Inflammation

CBD has a well-documented list of anti-inflammatory effects. Metabolic dysfunction often involves chronic inflammation. The pancreas is one of the most at-risk organs in obese and diabetic people.

The hyperactivity of the pancreas in an attempt to secrete extra insulin can cause inflammation in the entire gland. That chronic inflammation can damage the beta cells, which are the ones responsible for insulin secretion.

As the body becomes unable to produce sufficient levels of insulin — it brings you one step closer to diabetes and obesity.

As shown by a 2016 study, there’s a vivid link between inflammation and an overstimulated endocannabinoid system. The application of CBD can help fix this dysfunction. The antioxidant and anti-inflammatory effects of CBD curb inflammation and potentially save the pancreas against damage — reducing the risk of diabetes.

7. Repairs Liver Damage

Another common marker for obesity and diabetes is damage to liver cells. The liver plays a significant role in the conversion of stored and usable energy resources in the body.

Overburdening the liver with high sugar intake can prove disastrous for this system. Inflammation within the liver is an indicator of the onset of dysfunction and may lead to non-alcoholic fatty liver disease.

In 2015, researchers conducted a study on the impact of CBD and THCV on metabolic dysfunction and chronic liver damage.

The results suggested that these non-psychoactive cannabinoids reduce the buildup of triglycerides in the liver. Moreover, they lowered blood pressure and improved insulin resistance in human participants with type 2 diabetes. The scientists gave partial credit for these improvements to the anti-inflammatory properties of CBD.

Top 3 CBD Oil Recommendations for Weight Loss

There are hundreds of brands to choose from when it comes to the CBD oil space — many of which leave a lot to be desired in terms of transparency and quality.

To save you hours of research, I’d like to share my list of top 3 brands I would use to manage weight with CBD oil. Each of these companies offers nothing but high-quality products along with the third-party test results to back up their claims:

1. Royal CBD

Get 15% off all Royal CBD products. Use code “CFAH” at checkout.


  • Their CBD oil is made using full-spectrum extracts
  • Every batch of product has been tested in a third-party laboratory
  • Available in 4 different potency options
  • Also sold as gummies and softgel capsules


  • They’re priced higher than average — although the cost is well justified

What I Like About Royal CBD:

Royal CBD is a premium CBD brand that uses simple formulas in their products with only the highest quality ingredients.

I’m a fan of all Royal CBD products, but as far as weight loss goes, I’d stick to the oil or capsules mainly because they offer the full spectrum of cannabinoids, which has been proven superior to isolates in reducing inflammation. The second reason why I wouldn’t include the gummies in my supplementation regime is the sugar content. If you want to lose weight, cutting down on simple sugars is one of the most important steps, so instead, I’d look for more classic formats like oil or capsules.

What I love about their CBD oil is that it tastes much better than any other brand I’ve tried so far. That’s because the extract has been suspended in organic MCT oil that perfectly masks the botanical taste of hemp. I use the 500mg option, and I must admit it has done an excellent job of keeping my food cravings at bay.

If for some reason, you don’t want to use the classic oil, you can try their softgels. They allow for easier dosing and are more convenient to take than oil drops — not to mention they’re super easy to swallow.

2. Hemp Bombs


  • They offer a diverse product range
  • Each product is sent to a third-party lab for quality testing
  • Five potency options available
  • Up to 5000mg of CBD per bottle
  • THC-free


  • The extract used by Hemp Bombs aren’t quite as “premium” quality as Royal CBD
  • There’s no synergy from other cannabinoids

What I Like About Hemp Bombs:

Hemp Bombs offers one of the most diverse product ranges in the entire industry. Whether you want to buy oils, vape juices, pet treats, topicals, gummies, pet treats, CBD shots, and even beard balms — they have all these products in their assortment.

While their CBD oils aren’t of the same 5-star quality as Royal, the company does provide detailed lab analyses of every batch of their products. Besides, Hemp Bombs CBD oil can carry up to 5000mg of 99% pure CBD per bottle. You can use the stronger options to relieve anxiety and control your food cravings if you’re a compulsive eater.

3. CBDistillery


  • Their products are sourced from Colorado-grown hemp
  • Available as full-spectrum CBD or pure CBD oil (THC-free)
  • Each batch has been tested in a third-party laboratory for purity and potency
  • Five potency options to choose from
  • Very affordable deals


  • They don’t use organic hemp
  • Slightly lower quality than Royal CBD and Hemp Bombs

What I Like About CBDistillery:

This Colorado-based company is one of the pioneer brands in the industry and my first company I’ve bought CBD oil from.

Their product line includes both full-spectrum CBD and THC-free oils, with potency options starting at 250mg up to 5000mg of CBD. Because of that, you can adjust the strength of your oil to the specific problem you want to address.

On top of that, they offer very affordable deals; the 250mg bottle costs only $20, so if you’re using CBD oil for preventative supplementation and you don’t need high doses of this product, CBDistillery offers some of the best deals on the market.

How to Choose Between High-Quality and Low-Quality CBD Oil

Many health supplements in the US are unregulated — and CBD is one of them. This means that virtually anyone can buy the raw ingredients and formulate them into health supplements.

This leaves a lot of room for inferior CBD products on the market — some of which can be dangerous to your health.

With CBD oils, the biggest problem lies in the source of hemp and contamination of heavy metals, pesticides, and toxic solvents.

Luckily, there’s a foolproof way to eliminate the risk of getting snake oil instead of CBD oil — third-party testing in independent laboratories.

While this isn’t a mandatory step for CBD manufacturers, they can use lab reports to prove the quality of products they make. The lab will test the product for its cannabinoid content, as well as purity levels, providing a detailed analysis of the heavy metal, pesticide, solvent, and organic contamination contents.

Always look for these third-party tests on the manufacturer’s website. If a company fails to deliver such simple proof, they aren’t worth your time.

Weight Loss And the Endocannabinoid System

Better ratio of muscle to fat among cannabis users compared to non-users may sound counterintuitive. But this concept can be easily explained with the mechanism of the endocannabinoid system (ECS).

The ECS is a complex network of receptors and neurotransmitters found throughout the body, but its highest concentrations appear in the nervous and immune systems.

The neurotransmitters include molecules called endocannabinoids. The body releases them to send messages to cells via the cannabinoid receptors. Plant cannabinoids — or phytocannabinoids — like CBD or THC act much like the endocannabinoids.

The endocannabinoid system controls a wide range of vital processes, including mood, memory, inflammation, sensory perception, cognitive function, body temperature, appetite, and more.

The role of the endocannabinoid system is to maintain the balance in all of the above functions. When the balance gets compromised, a person will suffer from either under-activity or over-activity of the endocannabinoid system, which is when dysfunction sets in.

Many studies suggest that in the case of diabetes, metabolic syndrome, and obesity, there’s sound evidence of endocannabinoid system deficiency.

Here’s what Alicia Salazar, a New York state board-certified health coach, said about using CBD for weight loss:

“I don’t look at CBD as a magic bullet for weight loss. But along with a healthy diet — one that contains healthy fats, whole grains, grass-fed meat and dairy, and plenty of greens, without processed foods and sugar — sets the tone for a healthy weight. And for some, that can naturally include weight loss.”

Are There Any Concerns About CBD And Weight Gain?

The main concerns about CBD and weight gain come from the fear that cannabis and its compounds can stimulate the appetite.

As I said, this feature is typical of high-THC marijuana strains and products. In hemp-derived CBD oil, THC levels rarely exceed 0.3%, which isn’t enough to activate CB1 receptors to the point they will make you empty the entire fridge.

But even in marijuana-derived CBD oils, the ratios of THC to CBD make it unlikely that you’ll have munchies afterward.

Long story short, no, weight gain shouldn’t be your concern when taking CBD oil as long as it doesn’t contain more than trace amounts of THC.

The Final Verdict on CBD Oil for Weight Loss

The growing amount of evidence leans towards the health of the endocannabinoid system being tied to our metabolic performance. Scientists argue that the levels of endocannabinoid activity should be a new marker of metabolic health.

According to recent research, there’s great promise in developing potential cannabinoid-based treatments for obesity and diabetes.

It’s important to note, though, that CBD oil shouldn’t be used as a substitute for a balanced diet. If you want to make changes in your body, start with fixing your eating habits. Then choose a high-quality CBD oil — you can use my recommendations or do your research.

I hope this article has given you a better insight into the link between CBD and weight loss. Let me know how you incorporate CBD oil in your everyday routine!

  1. Gruden, G., Barutta, F., Kunos, G., & Pacher, P. (2016). Role of the endocannabinoid system in diabetes and diabetic complications. British journal of pharmacology, 173(7), 1116–1127.
  2. Rossi, F., Punzo, F., Umano, G. R., Argenziano, M., & Miraglia Del Giudice, E. (2018). Role of Cannabinoids in Obesity. International journal of molecular sciences, 19(9), 2690.
  3. Farrimond, J.A., Whalley, B.J., Williams, C.M. (2012) Cannabinol and Cannabidiol Exert Opposing effects on Rat Feeding Patterns. Psychopharmacology (Berlin), 223(1), 117–129.
  4. Parray, H.A., Yun, J.W. (2016). Cannabidiol Promotes Browning in 3T3-L1 Adipocytes. Molecular and Cellular Biochemistry, 416(1-2), 131–139.
  5. Dong, Z., Gong, H., Chen, Y., Wu, H., Wu, J., Deng, Y., & Song, X. (2018). LH-21, A Peripheral Cannabinoid Receptor 1 Antagonist, Exerts Favorable Metabolic Modulation Including Antihypertensive Effect in KKAy Mice by Regulating Inflammatory Cytokines and Adipokines on Adipose Tissue. Frontiers in endocrinology, 9, 167.
  6. Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, 2(1), 139–154.
  7. Ramlugon, S., Levendal, R.A., Frost, C.L. (2018) Time-dependent Effect of Phytocannabinoid Treatments in Fat Cells. Phytotherapy Research, 32(6), 1080–1089.
  8. Parray, H.A., Yun, J.W. (2016). Cannabidiol Promotes Browning in 3T3-L1 Adipocytes. Molecular and Cellular Biochemistry, 416(1-2), 131–139.
  9. Gruden, G., Barutta, F., Kunos, G., & Pacher, P. (2016). Role of the endocannabinoid system in diabetes and diabetic complications. British journal of pharmacology, 173(7), 1116–1127.
  10. Silvestri, C., Paris, D., Martella, A., Melck, D., Guadagnino, I., Cawthorne, M., Motta, A. & Di Marzo, V. (2015). Two Non-psychoactive Cannabinoids Reduce Intracellular Lipid Levels and InhibitHepatosteatosis. Journal of Hepatology, 62(6), 1382-1390.
Nina Julia

Nina created following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

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CBD Oil For Weight Loss: How Does It Help? Benefits & Dosage

Roughly 2 out of every 3 people are either overweight or obese.

CBD acts on chemical messengers that indirectly control our weight.

It helps support blood sugar balance, beta-oxidation, cortisol, and mitochondrial function.

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According to the National Health and Nutrition Examination Survey (NHANES), 2 out of every 3 people in America are overweight.

CBD oil has recently come to the surface as a promising weight loss supplement.

Can this controversial oil really offer the weight-loss advantages promised? Our verdict: yes, but not directly — CBD works through other systems in the body to return to an optimal state of health, which includes our body weight.

Here, we explore CBD and how it can be used to boost your weight loss program along with other diet and lifestyle changes.


Updated on January 12, 2022

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The Benefits of CBD For Weight Loss

The best way to lose weight, by far, is a regimented diet and exercise routine. Everything else is supplementary to this — including CBD.

With that said, adding CBD to your weight loss routine can go a long way in helping you shed extra weight more efficiently.

The benefits of CBD for weight loss include:
  • Reduces appetite to curb eating habits
  • Alleviates chronic inflammation associated with obesity
  • Alleviates digestive disorders and inflammation
  • Supports mitochondria function (where sugar and fat is burned for energy)

1. CBD Supports Mitochondria & Metabolic Health

You may remember from 8th-grade biology class that the mitochondria are the powerhouse of the cell.

It’s the part of the cell that’s responsible for converting sugars, fats, and even proteins into energy that the cell can use.

How Lazy Mitochondria Can Make Us Fat

When our mitochondria aren’t functioning optimally, which can happen for a variety of different reasons, it becomes harder to provide the body with the energy it needs and even harder to shed any extra weight.

What’s happening here is that the body is taking in lots of energy from our food, but our cells are having a hard time turning that energy into a currency we can actually use.

In order to prevent too much sugar and fat from building up in our bloodstream, the liver converts most of it into fat and puts it away in storage so we can use it at a later date.

The mitochondria are a key part of the metabolic system but they are far too small to fit in it on their own. This is where the endocannabinoid system comes in.

The ECS exerts its effects inside the cell, regulating the activity level of the mitochondria.

When they’re not working hard enough, the ECS whips them into shape. When they’re working too hard, producing more energy than we need, the ECS tells them to take the day off and slow down production.

This keeps us in metabolic balance, otherwise known as homeostasis.

When we take CBD, we’re essentially boosting the ability of the endocannabinoid system to keep control over the mitochondria.

For obese people, this almost always means whipping the mitochondria back into shape, converting more fats and sugars into energy that we can then burn off.

When combined with adequate exercise and nutritional support, this can significantly reduce overall fat storage by increasing the rate at which we burn through it.

Recent studies have shown that CBD plays a key modulating role in mitochondrial function [2, 3]. It does this indirectly through its role in regulating the endocannabinoid system as a whole.

2. CBD Normalizes Insulin Levels to Promote Fat Burning

Whenever we eat a meal, the nutrients from that meal are absorbed through the gut and into the bloodstream.

When these meals consist of energy-dense foods, like high-sugar and high-fat meals, the body gets a surge of energy in the bloodstream.

If we’re burning a ton of energy as well, through exercise and normal metabolism, then this isn’t a problem.

Energy in = energy out.

However, with obese people, there is a problem: they take a lot of energy in, but don’t put a lot of energy out. This allows things like sugar and fats to build up in the bloodstream, which is very dangerous.

High blood fats and sugars are closely linked with serious medical conditions like heart disease, diabetes, fatty liver disease, and even Alzheimer’s disease.

In order to keep the body safe, the liver steps up to convert most of the excess sugar into fat, which is then stored all around the body.

By storing this excess energy as fat, it doesn’t pose as much harm to the body.

The only way to stop this problem is by taking in less energy and burning more (less energy in and more energy out).

This is where diet and lifestyle changes come in. This is still the absolute best way to shed weight and keep it off.

However, when our body gets into a routine for too long, it’s very difficult to get out of it.

A lot of people, even after changing their diet and adding more exercise into their daily routine, find that they flatline with their weight loss. They lose a bunch of weight in the beginning, but shedding those last few pounds seems nearly impossible.

The problem lies with insulin levels.

How High Insulin Prevents Weight Loss

Insulin is a hormone released from the pancreas to shuttle sugar into the cells, where it’s then converted to energy.

Over many years of eating high sugar foods, insulin levels gradually rise – we call this hyperinsulinemia.

Even when we change our diet and lifestyle, insulin levels can remain high.

The important thing to note here is that whenever insulin levels are high in the bloodstream, we can’t burn fat.

This happens because insulin increases the uptake of fatty acids, favors the synthesis of lipids, and stops the breakage of fat. Altogether, these lead to energy storage,

And here is where CBD comes in.

CBD & Insulin

In a large study involving nearly 4700 patients with metabolic disease, CBD and marijuana use were shown to offer a 17% reduction in fasting insulin [4].

This is significant because if we can lower insulin levels, it becomes much easier to shed those last remaining pounds.

These effects are also extremely valuable for those with obesity, as it helps to stabilize insulin levels, and starts the process of curbing weight back down to healthy levels.

This is perhaps the most beneficial activity provided by CBD oil for obesity in the long run.

It’s important to note here that, although CBD is considered the main cannabinoid for producing these effects, it works better in a full-plant extract than in CBD isolates.

We always recommend going with a high-quality full-spectrum hemp extract for supporting insulin levels and cutting weight.

3. CBD Curbs Appetite to Decrease Calorie Intake

One of the main factors leading to obesity is our appetite.

Our body’s evolved for an environment where food was hard to come by, so we needed to make sure we stored enough of it to get through periods of time where food wasn’t available.

In the modern world, this has started to work against us.

Our appetites remain high, but food is always readily available. This allows us to eat our way to obesity far too easily.

Therefore, one of the best ways to cut weight and bring ourselves closer to a healthy range is by curbing our appetite as much as we can.

CBD is an excellent tool for achieving this.

You may be thinking:

“But marijuana makes us hungry, it gives us the munchies.”

This is true, but this is due to THC, not CBD.

Using psychoactive marijuana does stimulate the appetite, however, the CBD oil that contains only minuscule amounts of this particular cannabinoid actually has the opposite effect.

THC is considered an appetite stimulant, while CBD is considered an appetite suppressant.

It works by improving the sensitivity of the hypothalamus, the region of the brain responsible for controlling most of our homeostasis, including hunger levels.

When shopping for CBD oils to promote weight loss, make sure you buy something that includes mainly CBD, and only small amounts of THC to avoid causing the opposite effect and increasing hunger levels.

What is the Endocannabinoid System? What’s It’s Role in Weight Loss or Gain?

The endocannabinoid system (ECS for short) is a set of specialized, fatty-acid-based hormones/neurotransmitters that help regulate communication between a variety of different parts of the nervous system.

It’s used to regulate many different tissues in the body, including the neurological, metabolic, and immune systems.

Only in recent years have scientists started to uncover the many roles this system plays in the body, and how the cannabinoids from the marijuana and hemp plants are able to leverage this system to our advantage.

What is CBD?

CBD (cannabidiol) is just one of about 80 different cannabinoids. These are a group of chemicals found almost exclusively in the cannabis family of plants (Cannabaceae).

In order to classify as a cannabinoid, the compound needs to interact in some way with our endocannabinoid system.

In the cannabis plant, there are two cannabinoids that make up the majority of the plant constituent: CBD and THC (tetrahydrocannabinol).

Other cannabinoids include:

All cannabinoids have slightly different effects, but all will interact in some way with the endocannabinoid system.

When it comes to weight loss, the most important one to consider is CBD.

Cannabidiol is the predominant cannabinoid in cannabis oils made from hemp, but also makes up a large portion of marijuana oils that may or may not contain the psychoactive component, THC (tetrahydrocannabinol).

CBD impacts weight loss in 3 main ways:

  1. Supports our mitochondria & metabolic health
  2. Normalizes insulin levels to promote fat burning
  3. Lowers appetite to decrease calorie intake

We’ll get into the details of how each one of these works below.

Why Full-Spectrum CBD Is Better For Weight Loss

CBD is an excellent tool to address issues with obesity and promote weight loss in overweight people, but it can’t do it alone.

There are well over 200 different chemicals in the cannabis plant, and all of them are important.

Although CBD offers most of the benefits and is proven to provide weight loss support on its own, the other chemicals contained in the plant make it even more effective.

Some, like the terpenes in the essential oil of the plant, help CBD get absorbed by the intestinal tract, pass the blood-brain barrier, or slow the breakdown of CBD by the liver.

We call this the entourage effect because both CBD and THC are much stronger when they have their entourage of other terpenes, flavonoids, and cannabinoids along with them.

This is why we always prefer to use a full-spectrum extract for weight loss.

You can find CBD isolates which promise higher concentrations of CBD than their full-spectrum counterparts, but these don’t work nearly as well as an extract with the entourage included.

How to Use CBD for Weight Loss

Now that we’ve gone over how CBD helps with weight loss, let’s talk about how it can be used effectively.

As mentioned, make sure to go with a full spectrum hemp extract, rather than a CBD isolate or something that contains high amounts of THC.

Once you’ve found a good CBD oil, it’s time to figure out the right dose.

We recently made a guide to dosing CBD oil to help you figure out the right dose to start with.

Weight loss doesn’t happen overnight, no matter what those late-night infomercials promise.

The trick to successful weight loss is to look at it as a long-term lifestyle change. Don’t expect to lose 20 pounds by next week, or even the week after. Take it slow, and make the changes permanent.

Changing your diet to something with less refined carbohydrates and processed foods, and more vegetables will go a long way in shedding those extra pounds.

Additionally, adding as little as 30 minutes of mild-moderate exercise each day will help you burn unused energy, and get the fat burning.

CBD oil should be taken every day to start conditioning the appetite and mitochondria back to healthy levels. Most users report about 2 weeks of regular use before they start to really see and feel the benefits of the CBD oil on their obesity.